In a significant move towards reducing the obesity and its related diseases in the country, India’s Central Drugs Standard Control Organization (CDSCO) approved tirzepatide as novel weight loss drug. India’s Health Silk Road initiative takes a new momentum with this approval in Indian healthcare system that addresses to more than 1.3 million population of India. With the changing lifestyle and modernization, millions of people and the young in particular have become prone to obesity and overweight along with the consequences like chronic liver disease, diabetes in extremely affected individuals.

Global Obesity/Overweight Data

According to World Health Organization obesity and overweight are main reasons for various diseases and it estimated in 2016, around 1.9 billion adults within the age of 18 and older were overweight and 650 million among them were obese in 2016. The statistics is alarming and varies from country to country:

United States: 42.4% adults were obese in 2017-2018.

United Kingdom: 2019 saw 28% adults obese.

India: though as a nation India’s obesity is low compared to other countries; its urban population is seen to be moderately high to high with around 20% of all men and more than 23% of all women are diagnosed as either overweight or obese.

Australia: 31% of the population was obese in 2018.

Middle East: Kuwait and Saudi Arabia are seen with highest obesity prevalence above 35% of adults.

Globally approved weight losing drugs

The famous weight losing tablets that have been approved by the leading health organization are:

For most weight loss drugs, their use is related to different side effects depending on the drug:

The most effective methods of losing weight include the following:

Weight loss drugs are potent, effective, but they have side effects. It is related to Glucagon-like peptide-1 receptor agonists or semaglutide.

Lifestyle changes:

1. Diet: A balanced diet that includes a variety of fruits, vegetables, whole grains, lean proteins, fats, and oils. Nutritious foods help in building a strong body.

2. Physical activity: 150 minutes of moderate physical activity or 75 minutes of vigorous physical activity after every week. The exercises include strength training with weights.

3. Behavioral changes: Developing smart goals and identifying ways of tracking progress. For instance, conducting regular check-up, or joining a support group.

4. Monitoring: Regular monitoring by physicians is the key. The doctors will evaluate the following:

• Body mass index

• Cholesterol levels

• Baseline blood pressure

• Serum electrolytes

In conclusion, losing weight using drugs is one of the modern objectives that are aimed at balancing people’s weight. Weight loss drugs are effective tools for those patients with obesity. Thus, they are will cannot withstand doing exercise as the best method of losing weight. In the future, more weight loss drugs should be invented since the number of obese patients is increasing worldwide.

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