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Flash Chromatography Market

Flash Chromatography Market Size, Share & Segment, By Technique Type (Reverse Phase, Ion Exchange, Size Exclusion, Chiral Separation), By End User (Pharmaceutical & Biotechnology Industries, Contract Research Organization, Others), by Regions and Global Forecast 2022-2028

Report Id: SNS/HC/2482 | July 2022 | Region: Global | 129 Pages

Report Scope & Overview:

The Flash Chromatography Market Size was valued at USD 169.5 billion in 2021, and is expected to reach USD 243.4 billion by 2028, and grow at a CAGR of 5.3% over the forecast period 2022-2028.

Using air pressure, the purification technique of flash chromatography quickly separates substances. Smaller silica gel particles are used, and the gas pressure ranges from 50 to 200 psi, which makes it different from conventional column techniques. Developments in chromatography technology, like emerging pharmaceutical industry demands for purification and filtration, increased automation in chromatography tools, and rising government assets in the pharmaceutical and biotech sectors are some of the key factors expected to propel the flash chromatography market's increase in coming years to come.

Flash Chromatography Market

MARKET DYNAMICS

KEY DRIVERS

  • Increasingly more people are using flash chromatography worldwide.

  • Technology development in chromatography

RESTRAINTS

  • Absence of qualified staff to work the hardware

  • Expensive instrument prices

OPPORTUNITIES

  • Increased demand for herbal pharmaceuticals

  • Growing government initiatives to promote the use of herbal remedies will fuel market expansion.

IMPACT OF COVID-19

It is anticipated that during this pandemic time, the global market for flash chromatography will expand significantly. Flash chromatography systems are being used more frequently for drug development and research, which is anticipated to have a positive effect on market growth as the COVID-19 pandemic spreads. To better comprehend the Sars-CoV-2 virus and create novel drugs, vaccines, and diagnostic tools to help in the fight against the COVID-19 pandemic, scientists are using chromatography, a potent analytical technique used in laboratories. For instance, numerous pharma companies and academic institutions conduct COVID-19 drug research using Teledyne ISCO's (US) CombiFlash NextGen flash chromatography technology. Additionally, a significant step in the production process of vaccinations is the purifying and filtering of the vaccines at various stages. One of the most crucial purification procedures is the separation of the vaccine from the rest of the combination using chromatography columns. More than 288 COVID-19 vaccines are being explored, as per the WHO, with approximately 184 vaccinations reportedly in pre-clinical stages of investigation and 104 vaccines in various phases of clinical trials as of July 2021.

VALUE CHAIN ANALYSIS

Over the course of the forecast period, the market for flash chromatography is anticipated to grow significantly due to factors such as rising R&D investments by pharmaceutical and biotechnology firms and a variety of flash chromatography applications, including sample preparation, drug development, and others. The market's expansion is also being fueled by a sizable number of newly established players who are actively engaged in mergers, acquisitions, and strategic partnerships. The R&D and design phase, product production, product distribution and sales, and post-sales services make up the first four primary segments of the value chain analysis of the flash chromatography market.

By Technique Type

A wide variety of constituent types can benefit greatly from reverse phase flash chromatography as a purification method. The synthesis of polar chemicals and reaction mixtures with ever-increasing complexity can both benefit from it. As partitioning serves as a method of separation in reverse phase chromatography, hydrophobic substances will bind to the lipophilic stationary phase and evaporate when the solvent polarity decreases.

Specific to the purification and separation of differently charged or ionizable substances from organic or inorganic sources, such as proteins, nucleotides, DNA, peptides, enzymes, antibiotics, and vitamins, ion exchange chromatography was developed. A further factor contributing to the growth of the ion-exchange chromatography market is the increasing use of ion-exchange techniques in the agricultural, water, pharmaceutical, biotech, environmental, and food & beverage sectors. The method is also employed in the environmental testing sector to assess for quality, substance, and safety. The aforementioned elements are therefore encouraging market expansion.

By using a resin that is tightly packed in a column, size exclusion chromatography (SEC) divides molecules into different sizes as they pass through. SEC has the benefit of allowing conditions to be changed without interfering with the separation to suit the kind of sample or the needs for additional purification, analysis, or storage. It helps to evaluate the stability and properties of naturally occurring organic materials in water as well as the fractionation of proteins and other water-soluble polymers.

One of the best ways to separate enantiomers is through chiral separation utilizing high-performance liquid chromatography and a chiral stationary phase. The chiral separation industry is growing, which is why chiral separation techniques are increasingly being used in the pharmaceutical, biotechnology, and food and beverage industries. For toxicological investigations, biological testing, and clinical testing, pure enantiomers are necessary in the pharmaceutical and biotechnology sectors.

By End User

Owing to the expanding R&D expenditure and increasing importance of flash chromatography systems in drug R&D, impurity isolation during drug purification, and drug method development and validation, the pharmaceutical and biotechnology industry segment retained the largest market share.

A variety of clinical research services such as drug discovery through pharmacovigilance, post-approval services and more are provided by the contract research organization to pharmaceutical, biotech and healthcare companies. For clinical trials, the sponsoring organization hires a contract research firm on a project-by-project basis. For various clinical research purposes that require separation or purification of materials, contract research organizations often use flash chromatography procedures.

Other end users of flash chromatography include research and academic institutions, as well as the food and environmental industries. In the food industry, flash chromatography is used for the analysis of sugar content, aflatoxin in food detection and a number of other determinations of organic chemicals.

COMPETITIVE LANDSCAPE

Some of the major key players are as follows: Agilent Technologies, Inc., Biotage, GE Healthcare, Tosoh Corporation, Gilson, Inc., Interchim SA, Thermo Fisher Scientific, PerkinElmer, Inc., Waters Corporation, Teledyne ISCO, Shimadzu Corporation, and other players.

MARKET SEGMENTS:

By Technique Type

  • Reverse Phase

  • Ion Exchange

  • Size Exclusion

  • Chiral Separation

By End User

  • Pharmaceutical & Biotechnology Industries

  • Contract Research Organization

  • Others

Flash Chromatography Market

REGIONAL ANALYSIS

As a result of increased purchases of analytical equipment and the concentration of producers in this region, North America is anticipated to maintain its position as the world's largest market for flash chromatography during the foreseeable period. Due to the increase in the purchase of flash chromatography systems driven by assessments in government investments in Asian countries, Asia-Pacific is predicted to experience the biggest growth throughout the same forecasted period.

REGIONAL COVERAGE

  • North America

    • USA

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

    • The Netherlands

    • Rest of Europe

  • Asia-Pacific

    • Japan

    • south Korea

    • China

    • India

    • Australia

    • Rest of Asia-Pacific

  • The Middle East & Africa

    • Israel

    • UAE

    • South Africa

    • Rest of Middle East & Africa

  • Latin America

    • Brazil

    • Argentina

    • Rest of Latin America

 

Flash Chromatography Market Report Scope:
Report Attributes Details
Market Size in 2021 US$ 169.5 Billion
Market Size by 2028 US$ 243.4 Billion
CAGR CAGR of 5.3% From 2022 to 2028
Base Year 2021
Forecast Period 2022-2028
Historical Data 2017-2020
Report Scope & Coverage Market Size, Segments Analysis, Competitive  Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook
Key Segments • By Technique Type (Reverse Phase, Ion Exchange, Size Exclusion, Chiral Separation)
• By End User (Pharmaceutical & Biotechnology Industries, Contract Research Organization, Others)
Regional Analysis/Coverage North America (USA, Canada, Mexico), Europe
(Germany, UK, France, Italy, Spain, Netherlands,
Rest of Europe), Asia-Pacific (Japan, South Korea,
China, India, Australia, Rest of Asia-Pacific), The
Middle East & Africa (Israel, UAE, South Africa,
Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America)
Company Profiles Agilent Technologies, Inc., Biotage, GE Healthcare, Tosoh Corporation, Gilson, Inc., Interchim SA, Thermo Fisher Scientific, PerkinElmer, Inc., Waters Corporation, Teledyne ISCO, Shimadzu Corporation, and other players.
Key Drivers • Increasingly more people are using flash chromatography worldwide.
• Technology development in chromatography
RESTRAINTS • Absence of qualified staff to work the hardware
• Expensive instrument prices


Frequently Asked Questions (FAQ) :

Ans. Flash Chromatography Market Size was valued at USD 169.5 billion in 2021.

Ans. Increasingly more people are using flash chromatography worldwide, and Technology development in chromatography are the key drivers of the Flash Chromatography market

 Ans. North America is anticipated to maintain its position as the world's largest market for flash chromatography during the foreseeable period

Ans. Manufacturer and service provider, research institutes, university and private libraries, suppliers and distributers. 

Ans. Flash Chromatography market is divided in two segments and they are By Technique Type, and By End User


Table of Contents

 

1. Introduction

1.1 Market Definition

1.2 Scope

1.3 Research Assumptions

 

2. Research Methodology

 

3. Market Dynamics

3.1 Drivers

3.2 Restraints

3.3 Opportunities

3.4 Challenges

 

4. Impact Analysis

4.1 COVID 19 Impact Analysis

4.2 Impact of Ukraine ware

 

5. Value Chain Analysis

 

6. Porter’s 5 forces model

 

7.  PEST Analysis

  

8. Flash Chromatography Market Segmentation, By Technique Type

8.1 Reverse Phase

8.2 Ion Exchange

8.3 Size Exclusion

8.4 Chiral Separation

 

9. Flash Chromatography Market Segmentation, By End User

9.1 Pharmaceutical & Biotechnology Industries

9.2 Contract Research Organization

9.3 Others

 

10. Regional Analysis

10.1 Introduction

10.2 North America

10.2.1 USA

10.2.2 Canada

10.2.3 Mexico

10.3 Europe

10.3.1 Germany

10.3.2 UK

10.3.3 France

10.3.4 Italy

10.3.5 Spain

10.3.6 The Netherlands

10.3.7 Rest of Europe

10.4 Asia-Pacific

10.4.1 Japan

10.4.2 South Korea

10.4.3 China

10.4.4 India

10.4.5 Australia

10.4.6 Rest of Asia-Pacific

10.5 The Middle East & Africa

10.5.1 Israel

10.5.2 UAE

10.5.3 South Africa

10.5.4 Rest

10.6 Latin America

10.6.1 Brazil

10.6.2 Argentina

10.6.3 Rest of Latin America

 

11.Company Profiles

11.1 Agilent Technologies, Inc.

              11.1.1 Financial

11.1.2 Products/ Services Offered

11.1.3 SWOT Analysis

11.1.4 The SNS view

11.2 Biotage

11.3 GE Healthcare

11.4 Tosoh Corporation

11.5 Gilson, Inc.

11.6 Interchim SA

11.7 Thermo Fisher Scientific

11.8 PerkinElmer, Inc.

11.9 Waters Corporation

11.10 Teledyne ISCO

 

12.Competitive Landscape

12.1 Competitive Benchmark

12.2 Market Share analysis

12.3 Recent Developments

 

13.Conclusion

 

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Secondary Research or Desk Research is as the name suggests is a research process wherein, we collect data through the readily available information. In this process we use various paid and unpaid databases which our team has access to and gather data through the same. This includes examining of listed companies’ annual reports, Journals, SEC filling etc. Apart from this our team has access to various associations across the globe across different industries. Lastly, we have exchange relationships with various university as well as individual libraries.

Secondary Research

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