Flash Chromatography Market Report Scope & Overview:

The Flash Chromatography Market Size was valued at USD 178.48 million in 2022, and is expected to reach USD 269.78 million by 2030 and grow at a CAGR of 5.3% over the forecast period 2023-2030.

Using air pressure, the purification technique of flash chromatography quickly separates substances. Smaller silica gel particles are used, and the gas pressure ranges from 50 to 200 psi, which makes it different from conventional column techniques. Developments in chromatography technology, like emerging pharmaceutical industry demands for purification and filtration, increased automation in chromatography tools, and rising government assets in the pharmaceutical and biotech sectors are some of the key factors expected to propel the flash chromatography market's increase in coming years to come.

Flash Chromatography Market Revenue Analysis

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  • Increasingly more people are using flash chromatography worldwide.

  • Technology development in chromatography


  • Absence of qualified staff to work the hardware

  • Expensive instrument prices


  • Increased demand for herbal pharmaceuticals

  • Growing government initiatives to promote the use of herbal remedies will fuel market expansion.


It is anticipated that during this pandemic time, the global market for flash chromatography will expand significantly. Flash chromatography systems are being used more frequently for drug development and research, which is anticipated to have a positive effect on market growth as the COVID-19 pandemic spreads. To better comprehend the Sars-CoV-2 virus and create novel drugs, vaccines, and diagnostic tools to help in the fight against the COVID-19 pandemic, scientists are using chromatography, a potent analytical technique used in laboratories. For instance, numerous pharma companies and academic institutions conduct COVID-19 drug research using Teledyne ISCO's (US) CombiFlash NextGen flash chromatography technology. Additionally, a significant step in the production process of vaccinations is the purifying and filtering of the vaccines at various stages. One of the most crucial purification procedures is the separation of the vaccine from the rest of the combination using chromatography columns. More than 288 COVID-19 vaccines are being explored, as per the WHO, with approximately 184 vaccinations reportedly in pre-clinical stages of investigation and 104 vaccines in various phases of clinical trials as of July 2021.


Over the course of the forecast period, the market for flash chromatography is anticipated to grow significantly due to factors such as rising R&D investments by pharmaceutical and biotechnology firms and a variety of flash chromatography applications, including sample preparation, drug development, and others. The market's expansion is also being fueled by a sizable number of newly established players who are actively engaged in mergers, acquisitions, and strategic partnerships. The R&D and design phase, product production, product distribution and sales, and post-sales services make up the first four primary segments of the value chain analysis of the flash chromatography market.

By Technique Type

A wide variety of constituent types can benefit greatly from reverse phase flash chromatography as a purification method. The synthesis of polar chemicals and reaction mixtures with ever-increasing complexity can both benefit from it. As partitioning serves as a method of separation in reverse phase chromatography, hydrophobic substances will bind to the lipophilic stationary phase and evaporate when the solvent polarity decreases.

Specific to the purification and separation of differently charged or ionizable substances from organic or inorganic sources, such as proteins, nucleotides, DNA, peptides, enzymes, antibiotics, and vitamins, ion exchange chromatography was developed. A further factor contributing to the growth of the ion-exchange chromatography market is the increasing use of ion-exchange techniques in the agricultural, water, pharmaceutical, biotech, environmental, and food & beverage sectors. The method is also employed in the environmental testing sector to assess for quality, substance, and safety. The aforementioned elements are therefore encouraging market expansion.

By using a resin that is tightly packed in a column, size exclusion chromatography (SEC) divides molecules into different sizes as they pass through. SEC has the benefit of allowing conditions to be changed without interfering with the separation to suit the kind of sample or the needs for additional purification, analysis, or storage. It helps to evaluate the stability and properties of naturally occurring organic materials in water as well as the fractionation of proteins and other water-soluble polymers.

One of the best ways to separate enantiomers is through chiral separation utilizing high-performance liquid chromatography and a chiral stationary phase. The chiral separation industry is growing, which is why chiral separation techniques are increasingly being used in the pharmaceutical, biotechnology, and food and beverage industries. For toxicological investigations, biological testing, and clinical testing, pure enantiomers are necessary in the pharmaceutical and biotechnology sectors.

By End User

Owing to the expanding R&D expenditure and increasing importance of flash chromatography systems in drug R&D, impurity isolation during drug purification, and drug method development and validation, the pharmaceutical and biotechnology industry segment retained the largest market share.

A variety of clinical research services such as drug discovery through pharmacovigilance, post-approval services and more are provided by the contract research organization to pharmaceutical, biotech and healthcare companies. For clinical trials, the sponsoring organization hires a contract research firm on a project-by-project basis. For various clinical research purposes that require separation or purification of materials, contract research organizations often use flash chromatography procedures.

Other end users of flash chromatography include research and academic institutions, as well as the food and environmental industries. In the food industry, flash chromatography is used for the analysis of sugar content, aflatoxin in food detection and a number of other determinations of organic chemicals.


By Technique Type

  • Reverse Phase

  • Ion Exchange

  • Size Exclusion

  • Chiral Separation

By End User

  • Pharmaceutical & Biotechnology Industries

  • Contract Research Organization

  • Others

Flash Chromatography Market Segmentation Analysis

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As a result of increased purchases of analytical equipment and the concentration of producers in this region, North America is anticipated to maintain its position as the world's largest market for flash chromatography during the foreseeable period. Due to the increase in the purchase of flash chromatography systems driven by assessments in government investments in Asian countries, Asia-Pacific is predicted to experience the biggest growth throughout the same forecasted period.


  • North America

    • USA

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

    • The Netherlands

    • Rest of Europe

  • Asia-Pacific

    • Japan

    • south Korea

    • China

    • India

    • Australia

    • Rest of Asia-Pacific

  • The Middle East & Africa

    • Israel

    • UAE

    • South Africa

    • Rest of Middle East & Africa

  • Latin America

    • Brazil

    • Argentina

    • Rest of Latin America


Major key players are Agilent Technologies, Inc., Biotage, GE Healthcare, Tosoh Corporation, Gilson, Inc., Interchim SA, Thermo Fisher Scientific, PerkinElmer, Inc., Waters Corporation, Teledyne ISCO, Shimadzu Corporation, and Other Players.

Tosoh Corporation-Company Financial Analysis

Company Landscape Analysis

Flash Chromatography Market Report Scope:

Report Attributes Details
Market Size in 2022 US$ 178.48 Million
Market Size by 2030 US$ 269.78 Million
CAGR CAGR of 5.3% From 2023 to 2030
Base Year 2022
Forecast Period 2023-2030
Historical Data 2020-2021
Report Scope & Coverage Market Size, Segments Analysis, Competitive  Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook
Key Segments • By Technique Type (Reverse Phase, Ion Exchange, Size Exclusion, Chiral Separation)
• By End User (Pharmaceutical & Biotechnology Industries, Contract Research Organization, Others)
Regional Analysis/Coverage North America (USA, Canada, Mexico), Europe
(Germany, UK, France, Italy, Spain, Netherlands,
Rest of Europe), Asia-Pacific (Japan, South Korea,
China, India, Australia, Rest of Asia-Pacific), The
Middle East & Africa (Israel, UAE, South Africa,
Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America)
Company Profiles Agilent Technologies, Inc., Biotage, GE Healthcare, Tosoh Corporation, Gilson, Inc., Interchim SA, Thermo Fisher Scientific, PerkinElmer, Inc., Waters Corporation, Teledyne ISCO, Shimadzu Corporation, and other players.
Key Drivers • Increasingly more people are using flash chromatography worldwide.
• Technology development in chromatography
RESTRAINTS • Absence of qualified staff to work the hardware
• Expensive instrument prices

Frequently Asked Questions

Ans. The Flash Chromatography Market Size was valued at USD 178.48 million in 2022.

Ans. Increasingly more people are using flash chromatography worldwide, and Technology development in chromatography are the key drivers of the Flash Chromatography market

 Ans. North America is anticipated to maintain its position as the world's largest market for flash chromatography during the foreseeable period

Ans: The Flash Chromatography market is growing at a CAGR of 5.3% over the forecast period 2023-2030.

Ans. Flash Chromatography market is divided in two segments and they are By Technique Type, and By End User

Table of Contents

1. Introduction

1.1 Market Definition

1.2 Scope

1.3 Research Assumptions

2. Research Methodology

3. Market Dynamics

3.1 Drivers

3.2 Restraints

3.3 Opportunities

3.4 Challenges

4. Impact Analysis

4.1 COVID-19 Impact Analysis

4.2 Impact of Ukraine- Russia War

4.3 Impact of Ongoing Recession

4.3.1 Introduction

4.3.2 Impact on major economies US Canada Germany France United Kingdom China Japan South Korea Rest of the World

5. Value Chain Analysis

6. Porter’s 5 forces model

7.  PEST Analysis


8. Flash Chromatography Market Segmentation, By Technique Type

8.1 Reverse Phase

8.2 Ion Exchange

8.3 Size Exclusion

8.4 Chiral Separation

9. Flash Chromatography Market Segmentation, By End User

9.1 Pharmaceutical & Biotechnology Industries

9.2 Contract Research Organization

9.3 Others

10. Regional Analysis

10.1 Introduction

10.2 North America

10.2.1 USA

10.2.2 Canada

10.2.3 Mexico

10.3 Europe

10.3.1 Germany

10.3.2 UK

10.3.3 France

10.3.4 Italy

10.3.5 Spain

10.3.6 The Netherlands

10.3.7 Rest of Europe

10.4 Asia-Pacific

10.4.1 Japan

10.4.2 South Korea

10.4.3 China

10.4.4 India

10.4.5 Australia

10.4.6 Rest of Asia-Pacific

10.5 The Middle East & Africa

10.5.1 Israel

10.5.2 UAE

10.5.3 South Africa

10.5.4 Rest

10.6 Latin America

10.6.1 Brazil

10.6.2 Argentina

10.6.3 Rest of Latin America

11. Company Profiles

11.1 Agilent Technologies, Inc.

11.1.1 Financial

11.1.2 Products/ Services Offered

11.1.3 SWOT Analysis

11.1.4 The SNS view

11.2 Biotage

11.3 GE Healthcare

11.4 Tosoh Corporation

11.5 Gilson, Inc.

11.6 Interchim SA

11.7 Thermo Fisher Scientific

11.8 PerkinElmer, Inc.

11.9 Waters Corporation

11.10 Teledyne ISCO

12. Competitive Landscape

12.1 Competitive Benchmark

12.2 Market Share Analysis

12.3 Recent Developments

13. Conclusion

An accurate research report requires proper strategizing as well as implementation. There are multiple factors involved in the completion of good and accurate research report and selecting the best methodology to compete the research is the toughest part. Since the research reports we provide play a crucial role in any company’s decision-making process, therefore we at SNS Insider always believe that we should choose the best method which gives us results closer to reality. This allows us to reach at a stage wherein we can provide our clients best and accurate investment to output ratio.

Each report that we prepare takes a timeframe of 350-400 business hours for production. Starting from the selection of titles through a couple of in-depth brain storming session to the final QC process before uploading our titles on our website we dedicate around 350 working hours. The titles are selected based on their current market cap and the foreseen CAGR and growth.


The 5 steps process:

Step 1: Secondary Research:

Secondary Research or Desk Research is as the name suggests is a research process wherein, we collect data through the readily available information. In this process we use various paid and unpaid databases which our team has access to and gather data through the same. This includes examining of listed companies’ annual reports, Journals, SEC filling etc. Apart from this our team has access to various associations across the globe across different industries. Lastly, we have exchange relationships with various university as well as individual libraries.

Secondary Research

Step 2: Primary Research

When we talk about primary research, it is a type of study in which the researchers collect relevant data samples directly, rather than relying on previously collected data.  This type of research is focused on gaining content specific facts that can be sued to solve specific problems. Since the collected data is fresh and first hand therefore it makes the study more accurate and genuine.

We at SNS Insider have divided Primary Research into 2 parts.

Part 1 wherein we interview the KOLs of major players as well as the upcoming ones across various geographic regions. This allows us to have their view over the market scenario and acts as an important tool to come closer to the accurate market numbers. As many as 45 paid and unpaid primary interviews are taken from both the demand and supply side of the industry to make sure we land at an accurate judgement and analysis of the market.

This step involves the triangulation of data wherein our team analyses the interview transcripts, online survey responses and observation of on filed participants. The below mentioned chart should give a better understanding of the part 1 of the primary interview.

Primary Research

Part 2: In this part of primary research the data collected via secondary research and the part 1 of the primary research is validated with the interviews from individual consultants and subject matter experts.

Consultants are those set of people who have at least 12 years of experience and expertise within the industry whereas Subject Matter Experts are those with at least 15 years of experience behind their back within the same space. The data with the help of two main processes i.e., FGDs (Focused Group Discussions) and IDs (Individual Discussions). This gives us a 3rd party nonbiased primary view of the market scenario making it a more dependable one while collation of the data pointers.

Step 3: Data Bank Validation

Once all the information is collected via primary and secondary sources, we run that information for data validation. At our intelligence centre our research heads track a lot of information related to the market which includes the quarterly reports, the daily stock prices, and other relevant information. Our data bank server gets updated every fortnight and that is how the information which we collected using our primary and secondary information is revalidated in real time.

Data Bank Validation

Step 4: QA/QC Process

After all the data collection and validation our team does a final level of quality check and quality assurance to get rid of any unwanted or undesired mistakes. This might include but not limited to getting rid of the any typos, duplication of numbers or missing of any important information. The people involved in this process include technical content writers, research heads and graphics people. Once this process is completed the title gets uploader on our platform for our clients to read it.

Step 5: Final QC/QA Process:

This is the last process and comes when the client has ordered the study. In this process a final QA/QC is done before the study is emailed to the client. Since we believe in giving our clients a good experience of our research studies, therefore, to make sure that we do not lack at our end in any way humanly possible we do a final round of quality check and then dispatch the study to the client.

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