Report Id: SNS/HC/2482 | July 2022 | Region: Global | 129 Pages
Report Scope & Overview:
The Flash Chromatography Market Size was valued at USD 178.48 billion in 2022, and is expected to reach USD 269.78 billion by 2030, and grow at a CAGR of 5.3% over the forecast period 2023-2030.
Using air pressure, the purification technique of flash chromatography quickly separates substances. Smaller silica gel particles are used, and the gas pressure ranges from 50 to 200 psi, which makes it different from conventional column techniques. Developments in chromatography technology, like emerging pharmaceutical industry demands for purification and filtration, increased automation in chromatography tools, and rising government assets in the pharmaceutical and biotech sectors are some of the key factors expected to propel the flash chromatography market's increase in coming years to come.
Increasingly more people are using flash chromatography worldwide.
Technology development in chromatography
Absence of qualified staff to work the hardware
Expensive instrument prices
Increased demand for herbal pharmaceuticals
Growing government initiatives to promote the use of herbal remedies will fuel market expansion.
IMPACT OF COVID-19
It is anticipated that during this pandemic time, the global market for flash chromatography will expand significantly. Flash chromatography systems are being used more frequently for drug development and research, which is anticipated to have a positive effect on market growth as the COVID-19 pandemic spreads. To better comprehend the Sars-CoV-2 virus and create novel drugs, vaccines, and diagnostic tools to help in the fight against the COVID-19 pandemic, scientists are using chromatography, a potent analytical technique used in laboratories. For instance, numerous pharma companies and academic institutions conduct COVID-19 drug research using Teledyne ISCO's (US) CombiFlash NextGen flash chromatography technology. Additionally, a significant step in the production process of vaccinations is the purifying and filtering of the vaccines at various stages. One of the most crucial purification procedures is the separation of the vaccine from the rest of the combination using chromatography columns. More than 288 COVID-19 vaccines are being explored, as per the WHO, with approximately 184 vaccinations reportedly in pre-clinical stages of investigation and 104 vaccines in various phases of clinical trials as of July 2021.
VALUE CHAIN ANALYSIS
Over the course of the forecast period, the market for flash chromatography is anticipated to grow significantly due to factors such as rising R&D investments by pharmaceutical and biotechnology firms and a variety of flash chromatography applications, including sample preparation, drug development, and others. The market's expansion is also being fueled by a sizable number of newly established players who are actively engaged in mergers, acquisitions, and strategic partnerships. The R&D and design phase, product production, product distribution and sales, and post-sales services make up the first four primary segments of the value chain analysis of the flash chromatography market.
By Technique Type
A wide variety of constituent types can benefit greatly from reverse phase flash chromatography as a purification method. The synthesis of polar chemicals and reaction mixtures with ever-increasing complexity can both benefit from it. As partitioning serves as a method of separation in reverse phase chromatography, hydrophobic substances will bind to the lipophilic stationary phase and evaporate when the solvent polarity decreases.
Specific to the purification and separation of differently charged or ionizable substances from organic or inorganic sources, such as proteins, nucleotides, DNA, peptides, enzymes, antibiotics, and vitamins, ion exchange chromatography was developed. A further factor contributing to the growth of the ion-exchange chromatography market is the increasing use of ion-exchange techniques in the agricultural, water, pharmaceutical, biotech, environmental, and food & beverage sectors. The method is also employed in the environmental testing sector to assess for quality, substance, and safety. The aforementioned elements are therefore encouraging market expansion.
By using a resin that is tightly packed in a column, size exclusion chromatography (SEC) divides molecules into different sizes as they pass through. SEC has the benefit of allowing conditions to be changed without interfering with the separation to suit the kind of sample or the needs for additional purification, analysis, or storage. It helps to evaluate the stability and properties of naturally occurring organic materials in water as well as the fractionation of proteins and other water-soluble polymers.
One of the best ways to separate enantiomers is through chiral separation utilizing high-performance liquid chromatography and a chiral stationary phase. The chiral separation industry is growing, which is why chiral separation techniques are increasingly being used in the pharmaceutical, biotechnology, and food and beverage industries. For toxicological investigations, biological testing, and clinical testing, pure enantiomers are necessary in the pharmaceutical and biotechnology sectors.
By End User
Owing to the expanding R&D expenditure and increasing importance of flash chromatography systems in drug R&D, impurity isolation during drug purification, and drug method development and validation, the pharmaceutical and biotechnology industry segment retained the largest market share.
A variety of clinical research services such as drug discovery through pharmacovigilance, post-approval services and more are provided by the contract research organization to pharmaceutical, biotech and healthcare companies. For clinical trials, the sponsoring organization hires a contract research firm on a project-by-project basis. For various clinical research purposes that require separation or purification of materials, contract research organizations often use flash chromatography procedures.
Other end users of flash chromatography include research and academic institutions, as well as the food and environmental industries. In the food industry, flash chromatography is used for the analysis of sugar content, aflatoxin in food detection and a number of other determinations of organic chemicals.
Some of the major key players are as follows: Agilent Technologies, Inc., Biotage, GE Healthcare, Tosoh Corporation, Gilson, Inc., Interchim SA, Thermo Fisher Scientific, PerkinElmer, Inc., Waters Corporation, Teledyne ISCO, Shimadzu Corporation, and other players.
By Technique Type
By End User
Pharmaceutical & Biotechnology Industries
Contract Research Organization
As a result of increased purchases of analytical equipment and the concentration of producers in this region, North America is anticipated to maintain its position as the world's largest market for flash chromatography during the foreseeable period. Due to the increase in the purchase of flash chromatography systems driven by assessments in government investments in Asian countries, Asia-Pacific is predicted to experience the biggest growth throughout the same forecasted period.
Rest of Europe
Rest of Asia-Pacific
The Middle East & Africa
Rest of Middle East & Africa
Rest of Latin America
|Market Size in 2022||US$ 178.48 Billion|
|Market Size by 2030||US$ 269.78 Billion|
|CAGR||CAGR of 5.3% From 2023 to 2030|
|Report Scope & Coverage||Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook|
|Key Segments||• By Technique Type (Reverse Phase, Ion Exchange, Size Exclusion, Chiral Separation)
• By End User (Pharmaceutical & Biotechnology Industries, Contract Research Organization, Others)
|Regional Analysis/Coverage||North America (USA, Canada, Mexico), Europe
(Germany, UK, France, Italy, Spain, Netherlands,
Rest of Europe), Asia-Pacific (Japan, South Korea,
China, India, Australia, Rest of Asia-Pacific), The
Middle East & Africa (Israel, UAE, South Africa,
Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America)
|Company Profiles||Agilent Technologies, Inc., Biotage, GE Healthcare, Tosoh Corporation, Gilson, Inc., Interchim SA, Thermo Fisher Scientific, PerkinElmer, Inc., Waters Corporation, Teledyne ISCO, Shimadzu Corporation, and other players.|
|Key Drivers||• Increasingly more people are using flash chromatography worldwide.
• Technology development in chromatography
|RESTRAINTS||• Absence of qualified staff to work the hardware
• Expensive instrument prices
Frequently Asked Questions (FAQ) :
Ans. Flash Chromatography Market Size was valued at USD 169.5 billion in 2021.
Ans. Increasingly more people are using flash chromatography worldwide, and Technology development in chromatography are the key drivers of the Flash Chromatography market
Ans. North America is anticipated to maintain its position as the world's largest market for flash chromatography during the foreseeable period
Ans. Manufacturer and service provider, research institutes, university and private libraries, suppliers and distributers.
Ans. Flash Chromatography market is divided in two segments and they are By Technique Type, and By End User
Table of Contents
1.1 Market Definition
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
4. Impact Analysis
4.1 COVID-19 Impact Analysis
4.2 Impact of Ukraine- Russia war
4.3 Impact of ongoing Recession
4.3.2 Impact on major economies
220.127.116.11 United Kingdom
18.104.22.168 South Korea
22.214.171.124 Rest of the World
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8. Flash Chromatography Market Segmentation, By Technique Type
8.1 Reverse Phase
8.2 Ion Exchange
8.3 Size Exclusion
8.4 Chiral Separation
9. Flash Chromatography Market Segmentation, By End User
9.1 Pharmaceutical & Biotechnology Industries
9.2 Contract Research Organization
10. Regional Analysis
10.2 North America
10.3.6 The Netherlands
10.3.7 Rest of Europe
10.4.2 South Korea
10.4.6 Rest of Asia-Pacific
10.5 The Middle East & Africa
10.5.3 South Africa
10.6 Latin America
10.6.3 Rest of Latin America
11.1 Agilent Technologies, Inc.
11.1.2 Products/ Services Offered
11.1.3 SWOT Analysis
11.1.4 The SNS view
11.3 GE Healthcare
11.4 Tosoh Corporation
11.5 Gilson, Inc.
11.6 Interchim SA
11.7 Thermo Fisher Scientific
11.8 PerkinElmer, Inc.
11.9 Waters Corporation
11.10 Teledyne ISCO
12.1 Competitive Benchmark
12.2 Market Share analysis
12.3 Recent Developments
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