Hypoparathyroidism Treatment Market Report Scope & Overview:

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The Hypoparathyroidism Treatment Market Size was valued at USD 1.25 billion in 2023 and is expected to reach USD 2.25 billion by 2032 and grow at a CAGR of 6.8% over the forecast period 2024-2032.

Hypoparathyroidism is an uncommon disorder in which the activity of the parathyroid glands is reduced. The most prevalent cause of hypoparathyroidism in patients is when their parathyroid glands are removed or damaged during surgery. It is characterised by low parathyroid hormone secretion and can result in a significant decline in blood calcium levels as well as elevated phosphorus levels. Hypoparathyroidism symptoms range from modest tingling in the fingers, hands, or lips to severe and painful muscle cramps. Patients may experience convulsions and severe muscle cramps across their entire body. PTH shortage due to poor secretion and PTH inability to elicit a response from the bones and kidneys are the two types of hypoparathyroidism.

Supplementing the body with vitamins and minerals to restore calcium and phosphorus levels in the blood is one of the most popular hypoparathyroidism treatments. This can involve things like taking calcium carbonate tablets or getting a lot of vitamin D. The latter entails the ingestion of calcitriol and works by improving the body's calcium absorption rate. Other therapy option is to inject PTH every day using an FDA-approved injection.

Hypoparathyroidism is a condition in which the parathyroid glands do not produce enough hormone. Hypoparathyroidism can be caused by a wide variety of factors, including parathyroid gland injury or removal, DiGeorge syndrome, a genetic illness, autoimmune disease, cancer radiation treatment, and a low magnesium level. The purpose of parathyroid hormone is to keep the blood phosphorus and calcium levels in check. Hypoparathyroidism symptoms arise when the blood calcium level is low and the phosphorus level is high, causing the human body to exhibit symptoms such as muscle spasms, hair loss, dry skin, numbness, and convulsions. Both children and adults can develop hypoparathyroidism. If a child has hypoparathyroidism, symptoms include poor tooth development, vomiting, headaches, and mental issues.

MARKET DYNAMICS

DRIVERS

• Side effects Increased Thoracic Surgery and Cancer Incidence

• Investing more in R&D

• Government Support for New Drug Development

RESTRAINTS

• Side effects

• High cost

OPPORTUNITIES

• The increasing increase in demand for hypothyroidism biologics

• The rise of biologics is expected to bring lucrative

CHALLENGES

• Long Clinical Approval Processes

IMPACT OF COVID-19

The COVID-19 has had a significant effect on the health industry. While research trials for uncommon diseases have been delayed or postponed until 2020 due to the high emphasis placed on the development of life-saving medications, the market for hypoparathyroidism is projected to experience a short-term fall through 2021.

Government financing and subsidies to assist the development of new hormonal therapies, as well as the relaxing of regulatory laws, are projected to give significant chances for industry expansion. As a result, during the projected period, the market is expected to increase at a stable rate.

By Product:

Low parathyroid hormone secretions cause hypocalcemia. To normalize the insufficiency, doctors use calcium supplements as the first line of treatment.

By Route of Administration:

Due to increased product introductions and a strong pipeline, the oral sector had the highest market share by route of administration. Various elements, such as drug delivery speed, efficacy, and bioavailability, are expected to drive the oral segment's development. The oral mode of administration is effective for medications with a medium to high oral availability.

Oral therapies reduce the need for central lines for intravenous drug administration, lowering the risk of problems and hospitalization. One of the primary elements projected to promote segment growth is the advancement of promising new drugs and possible clinical pipeline candidates.

By Distribution:

Due to the general growing number of facilities and patient accessibility, hospital and retail sales are predicted to have the largest market share among all distribution channels. Additionally, one of the primary reasons driving market expansion throughout the projection period is the rapid delivery of medicines.

KEY MARKET SEGMENTS:

By Product Type

• Parathyroid Hormone

  • Natpara

• Vitamin D Analogue

  • Vitamin D2

  • Vitamin D3

• Calcium Supplements

By Route of Administration

• Parenteral

• Oral

By Distribution Channel

• Retail Pharmacies

• Hospital Pharmacies

• Online 

REGIONAL ANALYSIS

With a market share of 39.5% in 2021, North America dominated the Hypoparathyroidism Treatment Market. This can be linked to the rise in thyroid-related disorders and pharmaceutical companies' efforts to develop novel formulations. The market in this region is growing due to an increase in the number of thoracic procedures and the incidence of cancer.

However, due to increased government initiatives to promote awareness and the presence of generic manufacturers, Asia Pacific is expected to develop at a faster CAGR over the projection period 2022-2028. The market in this region is growing due to new technological breakthroughs in the treatment of hypoparathyroidism.

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REGIONAL COVERAGE:

• North America

  • USA

  • Canada

  • Mexico

• Europe

  • Germany

  • UK

  • France

  • Italy

  • Spain

  • The Netherlands

  • Rest of Europe

• Asia-Pacific

  • Japan

  • south Korea

  • China

  • India

  • Australia

  • Rest of Asia-Pacific

• The Middle East & Africa

  • Israel

  • UAE

  • South Africa

  • Rest of Middle East & Africa

• Latin America

  • Brazil

  • Argentina

  • Rest of Latin America

KEY PLAYERS:

Some of the major key players are as follows: Amgen Inc., Ascendis Pharma A/S, BionPharma Inc., Entera Bio Ltd., Extend Biosciences, Inc., F. Hoffmann-La Roche Ltd, ProLynx, Inc., Takeda Pharmaceutical Company Limited and Other Players