REPORT SCOPE & OVERVIEW
The MicroRNA Market size was USD 1.58 Billion in 2022 and is expected to Reach USD 4.03 Billion by 2030 and grow at a CAGR of 12.44% over the forecast period of 2023-2030.
The microRNA (miRNA) market refers to the global market for microRNA-based products and services. MicroRNAs are tiny non-coding RNA molecules that play an important function in gene expression regulation. They are involved in various biological processes, including development, cell differentiation, and disease progression. The miRNA market encompasses a wide range of applications, including diagnostics, therapeutics, and research tools.
MicroRNAs have gained significant attention as potential biomarkers for disease diagnosis and prognosis. They can be detected in various biological samples, such as blood, urine, and tissue, and their expression patterns can provide valuable information about diseases like cancer, cardiovascular disorders, and neurological conditions. Companies are developing miRNA-based diagnostic tests for early disease detection and personalized medicine. MicroRNA-based therapeutics aim to modulate gene expression and treat various diseases. By targeting specific microRNAs, researchers can potentially influence the expression of disease-related genes, leading to therapeutic benefits. This area is still in its early stages, with ongoing research and clinical trials focused on developing miRNA-based drugs for conditions like cancer, viral infections, and genetic disorders. MicroRNAs are essential tools for basic research and drug discovery.
Researchers use miRNA profiling techniques to study gene regulation, identify potential drug targets, and understand disease mechanisms. Several companies provide miRNA analysis kits, reagents, and services to facilitate miRNA research. The microRNA market has been experiencing steady growth due to the expanding understanding of microRNA biology, technological advancements in detection methods, and increasing demand for personalized medicine. However, it's important to note that the miRNA therapeutics segment is still in the early stages of development, and it may take time for miRNA-based drugs to gain regulatory approvals and enter the market. MiRNAs are becoming well known for their role in diagnosing and treating chronic illnesses such as cancer, liver disease, neurological disease, infectious disease, coronary heart disease, and metabolic disease. In the case of cancer, for example, overexpressed miRNAs are typically regarded as oncogenes. Some of these are expressed at extremely low levels in particular malignant cells and, in most cases, inhibit tumour formation. These miRNAs are known as tumour suppressor miRNAs. One of these tumour suppressor miRNAs is Let-7. As a result, one of the primary factors enhancing demand for such medications and fuelling the MicroRNA market growth is the therapeutic potential of miRNAs in many chronic disorders.
MicroRNAs have demonstrated potential as biomarkers for a variety of disorders. Because of their stability in physiological fluids and unique expression patterns, they are appealing candidates for diagnostic testing.
A growing number of clinical trials focusing on chronic diseases will drive market growth.
MiRNA's clinical and preclinical research applications are being expanded through ongoing investigations and clinical trials. An increasing body of evidence suggests that mRNAs have great usefulness as drug resistance modulators, biomarkers for pathogenic diseases, or medicines for medical intervention in practically all human health disorders. As a result, increasing the number of clinical trials for assessing the efficiency of miRNA in the treatment of various chronic illnesses is one of the significant factors boosting miRNA market expansion throughout the projection year.
Intellectual property rights play a crucial role in the development and commercialization of miRNA-based products. The existing IP landscape around miRNAs, including patents and licensing agreements, can create barriers to entry for new players.
MiRNA safety and toxicity concerns may limit market growth in this market.
Several therapeutic uses have been linked to the advantages of miRNA. It is used to treat chronic diseases such as cancer, cardiovascular problems, renal disease, and so on. However, their safety and toxicity are still a topic of debate.
As a result, numerous companies have halted clinical trials for novel miRNA-based medicines. Mirna Therapeutics, Inc., a clinical-stage pharmaceutical company, announced that it will stop the present Phase 1 study of MRX34, its investigational therapy for a variety of cancers. Due to many immune-related serious adverse events (SAE) recorded in patients given MRX34 throughout the trial, the firm voluntarily terminated enrolment and dosage in the clinical research.
miRNA-based therapeutics are still in the early stages of development, they hold significant promise for the treatment of various diseases. The ability of miRNAs to regulate multiple genes simultaneously opens up opportunities for targeted therapies and combination treatments.
Biomarker Discovery and Development is a big opportunity for this market.
MicroRNAs have shown promise as biomarkers for disease diagnosis, prognosis, and treatment response. The discovery and validation of new miRNA biomarkers can expand the range of diseases that can be detected and monitored. This presents opportunities for companies to develop innovative biomarker discovery platforms, diagnostic assays, and companion diagnostics for targeted therapies.
The development and commercialization of miRNA-based products can be costly, including research and development, clinical trials, manufacturing, and regulatory compliance.
Market Fragmentation and Competition are the biggest challenges for this market.
The miRNA market is characterized by fragmentation, with multiple companies, academic institutions, and research organizations working on different aspects of miRNA research, diagnostics, and therapeutics. This fragmentation can lead to challenges in standardization, lack of consensus on methodologies, and difficulties in establishing unified guidelines or regulations. Competition among market players can also impact market dynamics and commercialization efforts.
IMPACT OF RUSSIAN UKRAINE WAR
The Russian invasion of Ukraine was described as a barbaric act. This is a pointer to how the war between Ukraine & Russia affects the pharmaceutical business in this region. Russia supplies 35-40% of its raw material to the world, which holds a huge share. After this war, many countries stopped taking raw materials from Russia. Russia had a loss of 4-5% profit which is come from raw materials. however, for many countries, there has been a lot of good scope in this field, which will be a deal of profit in the future, due to this war, the raw material, shipping price, and energy prices have also increased. An increase of 2-3% has been seen, as a result of which there is a boom in the equipment related to treatment in the microRNA sectors.
IMPACT OF ONGOING RECESSION
The fact that a lot of money is being invested in developing novel therapies for individuals with life-threatening illnesses is a major contributor to the growth in medical prices in Asian countries. Modern medical treatments and therapies for diseases such as cancer, transplants, and so on are also becoming more expensive as they advance. Nowadays, the majority of the equipment used in top-tier hospitals is imported from other countries, which has resulted in an increase in medical prices.
Increased utilisation and nursing demands in ambulatory, hospital-based outpatient departments, home care, skilled nursing institutions, and hospice settings might result in an 8% to 10% yearly rise in registered nurse demand between 2021 and 2025. At the same time, higher-than-normal attrition (8% per year in 2021 and 2022 before returning to an estimated 2% to 5% in 2023) and retirements will outnumber new licensures, reducing the total number of registered nurses working in direct patient care just as the number of required roles grows. After 2022, the attrition rate should return to normal. This ongoing recession does not see a major impact on microRNA markets.
KEY MARKET SEGMENTS
By Products & Services
By End Users
Academic & Government Research Institutes
Biotechnology & Pharmaceutical Companies
Rest of Eastern Europe
Rest of Western Europe
Rest of Asia Pacific
Middle East & Africa
Rest of Middle East
Rest of Africa
Rest of Latin America
North America: Due to increased expenditures in research and development activities in the area, the region will continue its dominance over the worldwide market over the projection period. Furthermore, the existence of key competitors with the ability to engage in R&D activities adds to the growth of the market in North America. Along with major advances, the region's availability of easy and speedy procedures for obtaining approvals for microRNA biomarkers supplements the market's expansion. Massive contributors to the North American market include Synlogic, Thermo Fisher Scientific, ProMega Corporation, and SeqMatic.
Asia Pacific: The region's quickly growing population, rising frequency of cardiovascular disorders, higher need for microRNA-based therapeutics, and greater emphasis on research & development activities are just a few of the reasons driving market expansion. For example, MiRXES, located in Singapore, announced in 2022 its cooperation with the National University Heart Centres and the National Heart Centre, Singapore, to control pulmonary hypertension. The partnership has resulted in the commencement of Southeast Asia's first multi-centre research using early detection microRNA biomarkers. The centre’s goal is to employ microRNA biomarkers to diagnose pulmonary hypertension early.
Some major key players in MicroRNA Market are QIAGEN, Merck KGaA, Synlogic, Thermo Fisher Scientific Inc., Horizon Discovery Ltd., GeneCopoeia, Inc, New England Biolabs, NanoString, Quantabio, BioGenex and other players.
Synlogic-Company Financial Analysis
Sistemic Ltd: Sistemic Ltd announced the extension of their patent covering the use of microRNAs as predictive analytes for cellular function. The patent covers the investigation of microRNA expression in mesenchymal stem cells collected from multiple donors in order to find miRNAs that will be associated with cellular activities in order to help donor screening and the development of MSC-based cell treatments.
DiamiR: DiamiR got U.S. Patent clearance for miRNA-based systems for identifying and monitoring brain aging. The patent addresses the application of quantitative techniques for analyzing detectable miRNA in blood plasma and the brain as brain ageing indicators.
|Market Size in 2022
|US$ 1.58 Bn
|Market Size by 2030
|US$ 4.03 Bn
|CAGR of 12.44% From 2023 to 2030
|Report Scope & Coverage
|Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook
|• By Products & Services (Profiling, Quantification, and Localization)
• By Application (Neurological Disease, Cancer)
• By End User (Academic & Government Research Institutes, Biotechnology & Pharmaceutical Companies, Other)
|North America (US, Canada, Mexico), Europe (Eastern Europe [Poland, Romania, Hungary, Turkey, Rest of Eastern Europe] Western Europe] Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Austria, Rest of Western Europe]). Asia Pacific (China, India, Japan, South Korea, Vietnam, Singapore, Australia, Rest of Asia Pacific), Middle East & Africa (Middle East [UAE, Egypt, Saudi Arabia, Qatar, Rest of Middle East], Africa [Nigeria, South Africa, Rest of Africa], Latin America (Brazil, Argentina, Colombia Rest of Latin America)
|QIAGEN, Merck KGaA, Synlogic, Thermo Fisher Scientific Inc., Horizon Discovery Ltd., GeneCopoeia, Inc, New England Biolabs, NanoString, Quantabio, BioGenex
|• MicroRNAs have demonstrated potential as biomarkers for a variety of disorders. Because of their stability in physiological fluids and unique expression patterns, they are appealing candidates for diagnostic testing.
• A growing number of clinical trials focusing on chronic diseases will drive market growth.
|• Intellectual property rights play a crucial role in the development and commercialization of miRNA-based products. The existing IP landscape around miRNAs, including patents and licensing agreements, can create barriers to entry for new players.
• MiRNA safety and toxicity concerns may limit market growth in this market.
Ans: The MicroRNA Market is estimated to develop at a 12.64% CAGR.
Ans: The MicroRNA Market was valued at USD 1.58 billion in 2022 and is predicted to grow to USD 4.03 billion by 2030.
Ans: By Products & Services, The profiling, Quantification, and Localization segment will lead the market.
Ans: The increased need for improved diagnostic outcomes fuels and real-time polymerase chain reactions are expected to dominate the microRNA industry.
Ans: In 2022, microRNA-related profiling, localisation, and quantification services held a 24.84% share of the microRNA market. This is due to a rise in functional studies to examine the role of various miRNAs in various illnesses, as well as the increased usage of modern technologies like as NGS for reliable detection and quantification of miRNAs.
Table of Contents
1.1 Market Definition
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
4. Impact Analysis
4.1 Impact of Russia-Ukraine War
4.2 Impact of Ongoing Recession
4.2.2 Impact on major economies
126.96.36.199 United Kingdom
188.8.131.52 South Korea
184.108.40.206 Rest of the World
4.3 Supply Demand Gap Analysis
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8. MicroRNA Market Segmentation, By Products & Services
9. MicroRNA Market Segmentation, By Application
9.1 Neurological Disease
10. MicroRNA Market Segmentation, By End User
10.1 Academic & Government Research Institutes
10.2 Biotechnology & Pharmaceutical Companies
11. Regional Analysis
11.2 North America
11.2.1 North America MicroRNA Market by Country
11.2.2 North America MicroRNA Market by Products & Services
11.2.3 North America MicroRNA Market by Application
11.2.4 North America MicroRNA Market by End User
220.127.116.11 USA MicroRNA Market by Products & Services
18.104.22.168 USA MicroRNA Market by Application
22.214.171.124 USA MicroRNA Market by End User
126.96.36.199 Canada MicroRNA Market by Products & Services
188.8.131.52 Canada MicroRNA Market by Application
184.108.40.206 Canada MicroRNA Market by End User
220.127.116.11 Mexico MicroRNA Market by Products & Services
18.104.22.168 Mexico MicroRNA Market by Application
22.214.171.124 Mexico MicroRNA Market by End User
11.3.1 Eastern Europe
126.96.36.199 Eastern Europe MicroRNA Market by Country
188.8.131.52 Eastern Europe MicroRNA Market by Products & Services
184.108.40.206 Eastern Europe MicroRNA Market by Application
220.127.116.11 Eastern Europe MicroRNA Market by End User
18.104.22.168.1 Poland MicroRNA Market by Products & Services
22.214.171.124.2 Poland MicroRNA Market by Application
126.96.36.199.3 Poland MicroRNA Market by End User
188.8.131.52.1 Romania MicroRNA Market by Products & Services
184.108.40.206.2 Romania MicroRNA Market by Application
220.127.116.11.4 Romania MicroRNA Market by End User
18.104.22.168.1 Turkey MicroRNA Market by Products & Services
22.214.171.124.2 Turkey MicroRNA Market by Application
126.96.36.199.3 Turkey MicroRNA Market by End User
188.8.131.52 Rest of Eastern Europe
184.108.40.206.1 Rest of Eastern Europe MicroRNA Market by Products & Services
220.127.116.11.2 Rest of Eastern Europe MicroRNA Market by Application
18.104.22.168.3 Rest of Eastern Europe MicroRNA Market by End User
11.3.2 Western Europe
22.214.171.124 Western Europe MicroRNA Market by Country
126.96.36.199 Western Europe MicroRNA Market by Products & Services
188.8.131.52 Western Europe MicroRNA Market by Application
184.108.40.206 Western Europe MicroRNA Market by End User
220.127.116.11.1 Germany MicroRNA Market by Products & Services
18.104.22.168.2 Germany MicroRNA Market by Application
22.214.171.124.3 Germany MicroRNA Market by End User
126.96.36.199.1 France MicroRNA Market by Products & Services
188.8.131.52.2 France MicroRNA Market by Application
184.108.40.206.3 France MicroRNA Market by End User
220.127.116.11.1 UK MicroRNA Market by Products & Services
18.104.22.168.2 UK MicroRNA Market by Application
22.214.171.124.3 UK MicroRNA Market by End User
126.96.36.199.1 Italy MicroRNA Market by Products & Services
188.8.131.52.2 Italy MicroRNA Market by Application
184.108.40.206.3 Italy MicroRNA Market by End User
220.127.116.11.1 Spain MicroRNA Market by Products & Services
18.104.22.168.2 Spain MicroRNA Market by Application
22.214.171.124.3 Spain MicroRNA Market by End User
126.96.36.199.1 Netherlands MicroRNA Market by Products & Services
188.8.131.52.2 Netherlands MicroRNA Market by Application
184.108.40.206.3 Netherlands MicroRNA Market by End User
220.127.116.11.1 Switzerland MicroRNA Market by Products & Services
18.104.22.168.2 Switzerland MicroRNA Market by Application
22.214.171.124.3 Switzerland MicroRNA Market by End User
126.96.36.199.1 Austria MicroRNA Market by Products & Services
188.8.131.52.2 Austria MicroRNA Market by Application
184.108.40.206.3 Austria MicroRNA Market by End User
220.127.116.11 Rest of Western Europe
18.104.22.168.1 Rest of Western Europe MicroRNA Market by Products & Services
22.214.171.124.2 Rest of Western Europe MicroRNA Market by Application
126.96.36.199.3 Rest of Western Europe MicroRNA Market by End User
11.4.1 Asia-Pacific MicroRNA Market by Country
11.4.2 Asia-Pacific MicroRNA Market by Products & Services
11.4.3 Asia-Pacific MicroRNA Market by Application
11.4.4 Asia-Pacific MicroRNA Market by End User
188.8.131.52 China MicroRNA Market by Products & Services
184.108.40.206 China MicroRNA Market by End User
220.127.116.11 China MicroRNA Market by Application
18.104.22.168 India MicroRNA Market by Products & Services
22.214.171.124 India MicroRNA Market by Application
126.96.36.199 India MicroRNA Market by End User
188.8.131.52 Japan MicroRNA Market by Products & Services
184.108.40.206 Japan MicroRNA Market by Application
220.127.116.11 Japan MicroRNA Market by End User
11.4.8 South Korea
18.104.22.168 South Korea MicroRNA Market by Products & Services
22.214.171.124 South Korea MicroRNA Market by Application
126.96.36.199 South Korea MicroRNA Market by End User
188.8.131.52 Vietnam MicroRNA Market by Products & Services
184.108.40.206 Vietnam MicroRNA Market by Application
220.127.116.11 Vietnam MicroRNA Market by End User
18.104.22.168 Singapore MicroRNA Market by Products & Services
22.214.171.124 Singapore MicroRNA Market by Application
126.96.36.199 Singapore MicroRNA Market by End User
188.8.131.52 Australia MicroRNA Market by Products & Services
184.108.40.206 Australia MicroRNA Market by Application
220.127.116.11 Australia MicroRNA Market by End User
11.4.12 Rest of Asia-Pacific
18.104.22.168 Rest of Asia-Pacific MicroRNA Market by Products & Services
22.214.171.124 Rest of Asia-Pacific MicroRNA Market by Application
126.96.36.199 Rest of Asia-Pacific MicroRNA Market by End User
11.5 Middle East & Africa
11.5.1 Middle East
188.8.131.52 Middle East MicroRNA Market by Country
184.108.40.206 Middle East MicroRNA Market by Products & Services
220.127.116.11 Middle East MicroRNA Market by Application
18.104.22.168 Middle East MicroRNA Market by End User
22.214.171.124.1 UAE MicroRNA Market by Products & Services
126.96.36.199.2 UAE MicroRNA Market by Application
188.8.131.52.3 UAE MicroRNA Market by End User
184.108.40.206.1 Egypt MicroRNA Market by Products & Services
220.127.116.11.2 Egypt MicroRNA Market by Application
18.104.22.168.3 Egypt MicroRNA Market by End User
22.214.171.124 Saudi Arabia
126.96.36.199.1 Saudi Arabia MicroRNA Market by Products & Services
188.8.131.52.2 Saudi Arabia MicroRNA Market by Application
184.108.40.206.3 Saudi Arabia MicroRNA Market by End User
220.127.116.11.1 Qatar MicroRNA Market by Products & Services
18.104.22.168.2 Qatar MicroRNA Market by Application
22.214.171.124.3 Qatar MicroRNA Market by End User
126.96.36.199 Rest of Middle East
188.8.131.52.1 Rest of Middle East MicroRNA Market by Products & Services
184.108.40.206.2 Rest of Middle East MicroRNA Market by Application
220.127.116.11.3 Rest of Middle East MicroRNA Market by End User
18.104.22.168 Africa MicroRNA Market by Country
22.214.171.124 Africa MicroRNA Market by Products & Services
126.96.36.199 Africa MicroRNA Market by Application
188.8.131.52 Africa MicroRNA Market by End User
184.108.40.206.1 Nigeria MicroRNA Market by Products & Services
220.127.116.11.2 Nigeria MicroRNA Market by Application
18.104.22.168.3 Nigeria MicroRNA Market by End User
22.214.171.124 South Africa
126.96.36.199.1 South Africa MicroRNA Market by Products & Services
188.8.131.52.2 South Africa MicroRNA Market by Application
184.108.40.206.3 South Africa MicroRNA Market by End User
220.127.116.11 Rest of Africa
18.104.22.168.1 Rest of Africa MicroRNA Market by Products & Services
22.214.171.124.2 Rest of Africa MicroRNA Market by Application
126.96.36.199.3 Rest of Africa MicroRNA Market by End User
11.6 Latin America
11.6.1 Latin America MicroRNA Market by Country
11.6.2 Latin America MicroRNA Market by Products & Services
11.6.3 Latin America MicroRNA Market by Application
11.6.4 Latin America MicroRNA Market by End User
188.8.131.52 Brazil America MicroRNA Market by Products & Services
184.108.40.206 Brazil America MicroRNA Market by Application
220.127.116.11 Brazil America MicroRNA Market by End User
18.104.22.168 Argentina America MicroRNA Market by Products & Services
22.214.171.124 Argentina America MicroRNA Market by Application
126.96.36.199 Argentina America MicroRNA Market by End User
188.8.131.52 Colombia America MicroRNA Market by Products & Services
184.108.40.206 Colombia America MicroRNA Market by Application
220.127.116.11 Colombia America MicroRNA Market by End User
11.6.8 Rest of Latin America
18.104.22.168 Rest of Latin America MicroRNA Market by Products & Services
22.214.171.124 Rest of Latin America MicroRNA Market by Application
126.96.36.199 Rest of Latin America MicroRNA Market by End User
12 Company profile
12.1.1 Company Overview
12.1.3 Product/Services Offered
12.1.4 SWOT Analysis
12.1.5 The SNS View
12.2 Merck KGaA
12.2.1 Company Overview
12.2.3 Product/Services Offered
12.2.4 SWOT Analysis
12.2.5 The SNS View
12.3.1 Company Overview
12.3.3 Product/Services Offered
12.3.4 SWOT Analysis
12.3.5 The SNS View
12.4 Thermo Fisher Scientific Inc
12.4.1 Company Overview
12.4.3 Product/Services Offered
12.4.4 SWOT Analysis
12.4.5 The SNS View
12.5 Horizon Discovery Ltd
12.5.1 Company Overview
12.5.3 Product/Services Offered
12.5.4 SWOT Analysis
12.5.5 The SNS View
12.6 GeneCopoeia, Inc
12.6.1 Company Overview
12.6.3 Product/Services Offered
12.6.4 SWOT Analysis
12.6.5 The SNS View
12.7 New England Biolabs
12.7.1 Company Overview
12.7.3 Product/Services Offered
12.7.4 SWOT Analysis
12.7.5 The SNS View
12.8.1 Company Overview
12.8.3 Product/Services Offered
12.8.4 SWOT Analysis
12.8.5 The SNS View
12.9.1 Company Overview
12.9.3 Product/Services Offered
12.9.4 SWOT Analysis
12.9.5 The SNS View
12.10.1 Company Overview
12.10.3 Product/Services Offered
12.10.4 SWOT Analysis
12.10.5 The SNS View
13. Competitive Landscape
13.1 Competitive Benchmarking
13.2 Market Share Analysis
13.3 Recent Developments
13.3.1 Industry News
13.3.2 Company News
13.3.3 Mergers & Acquisitions
13. USE Cases and Best Practices
An accurate research report requires proper strategizing as well as implementation. There are multiple factors involved in the completion of good and accurate research report and selecting the best methodology to compete the research is the toughest part. Since the research reports we provide play a crucial role in any company’s decision-making process, therefore we at SNS Insider always believe that we should choose the best method which gives us results closer to reality. This allows us to reach at a stage wherein we can provide our clients best and accurate investment to output ratio.
Each report that we prepare takes a timeframe of 350-400 business hours for production. Starting from the selection of titles through a couple of in-depth brain storming session to the final QC process before uploading our titles on our website we dedicate around 350 working hours. The titles are selected based on their current market cap and the foreseen CAGR and growth.
The 5 steps process:
Step 1: Secondary Research:
Secondary Research or Desk Research is as the name suggests is a research process wherein, we collect data through the readily available information. In this process we use various paid and unpaid databases which our team has access to and gather data through the same. This includes examining of listed companies’ annual reports, Journals, SEC filling etc. Apart from this our team has access to various associations across the globe across different industries. Lastly, we have exchange relationships with various university as well as individual libraries.
Step 2: Primary Research
When we talk about primary research, it is a type of study in which the researchers collect relevant data samples directly, rather than relying on previously collected data. This type of research is focused on gaining content specific facts that can be sued to solve specific problems. Since the collected data is fresh and first hand therefore it makes the study more accurate and genuine.
We at SNS Insider have divided Primary Research into 2 parts.
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This step involves the triangulation of data wherein our team analyses the interview transcripts, online survey responses and observation of on filed participants. The below mentioned chart should give a better understanding of the part 1 of the primary interview.
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