Blood Grouping Reagents Market Report Scope & Overview:

The Blood Grouping Reagents Market Size was valued at USD 1.90 billion in 2022, and is expected to reach USD 4.11 billion by 2030 and grow at a CAGR of 10.1% over the forecast period 2023-2030.

Solutions known as blood grouping reagents can be used to distinguish between the ABO, Rhesus, Kell, and MNS blood groups. These distinctions between types of human blood are made based on whether red blood cells' surfaces contain antigens or not. The reagents may have an impact on the test red blood cells' tendency to aggregate and transmit antigen. There is no way to determine the absence of a specific antigen from the test red blood cells via clumping.

Blood Grouping Reagents Market Revenue Analysis

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  • The No. of Blood Donations is Increasing

  • An Increase in the Number of Emergencies, Trauma Cases, and Road Accidents That Require Blood Transfusions.

  • Blood group typing in prenatal testing is in greater demand.

  • Blood group typing is becoming more common in forensic sciences

  • The Blood Transfusion Market Will Grow as a Result of Strict Regulations


  • Concern about the effectiveness and precision of test kits



  • The dangers of blood transfusions


The introduction of the coronavirus had a negative effect on numerous industries worldwide. Due to limitations on production, the suspension of clinical studies, and R&D operations, the healthcare sector also suffered. However, a significant amount of blood grouping reagent items is needed for diagnostic purposes due to the rising number of COVID-19 patients. There is a tremendous global demand for the growing number of assay techniques available to determine whether patients have the coronavirus or not. The market players were under pressure to develop blood grouping reagent items because of the sudden increase in diagnostic procedures. Additionally, the need for blood grouping reagent products is being driven by the increase in RT-PCR and molecular assay testing for disease confirmation.

By Product & Service

Anti-A, Anti-AB, Anti-B, Anti-D (PK 1), Anti-D, Anti-D (PK 2), control reagents, and phenotyping reagents like Anti-C, Anti-E, Anti-c, Anti-e, and Anti-K are only a few examples of consumables used in blood grouping. A variety of businesses, including Merck KGaA, Bio-Rad Laboratories Inc., Novacyt SA, Beckman Coulter, Inc., Grifols SA, and Immucor, Inc., provide consumables to meet market demand.

The ABO grouping, antibody screening, Rh typing, and cross-matching tests utilised by the blood grouping instrument are used to determine blood type. These tools are used to examine blood groups and provide a number of advantages over tests carried out manually by technicians, including a decrease in human error.

By Technique

Blood screening and other mass testing and diagnostic applications have been directly impacted by the accelerating development of molecular biology techniques. The identification of blood groups has been effectively accomplished using PCR and microarray techniques. The antigen type of donor RBCs for transfusion and antibody identification reagent panels can be predicted using PCR-based assays.

An analytical technique used for blood grouping is known as an assay-based technique. Blood grouping is done using bead-based technology, such as the Luminex technique, and solid-phase assays like ELISA. Reagent antigens or antibodies attached to a surface are used in solid-phase tests (usually a microplate). Solid-phase assays are utilised by a number of automated analyzers for blood grouping.

A thorough blood-group variation profile is provided using massively parallel sequencing techniques. The development of this approach is hampered by a scarcity of skilled workers since it requires labor-intensive data analysis by blood-group genetics specialists.

A diagnostic method for identifying antibodies in serum is known as serology, which involves looking for antigens on the outside of blood cells. The increased demand for blood products for many different antigens cannot be met by this approach due to some of its drawbacks. The serology section is further divided into the following sub-segments: gel technique, erythrocytes magnetized technology (EMT), solid-phase red-cell adhesion (SPRCA), glass tube, glass slide, cassette/kits, and others.

By Test Type

The type of antigens that are found on RBCs are known as their phenotype. The 'type and screen' establishes the patient's ABO-Rh while screening for the presence of the most frequently discovered surprising antibodies. All patients who require transfusions undergo it. However, it is also possible to execute an extended antigen phenotype.

To determine whether an antibody to a red cell antigen has been generated, antibody screening is carried out. Antibody screening is done to look for antibodies in blood transfusion recipients, expectant mothers, those who might be having blood and plasma donors, and transfusion reactions.

To make sure the donor blood is compatible before a blood transfusion, crossmatching tests, which are among the most crucial serological testing, are carried out. The recipient's plasma is combined with donor blood cells in this procedure, and agglutination reactions are then looked for.

Analyzing the presence or absence of a specific antibody (qualitative) or the quantity of antibody present is a necessary step in the identification of an antibody (quantitative). Antibody identification testing is used for a variety of purposes, such as documenting exposure to an infectious or foreign agent, assessing immune status against a specific microorganism, diagnosing an autoimmune condition, determining the cause of a transfusion reaction or the rejection of an organ transplant, identifying an allergy, and tracking the progression of an infection or autoimmune process.

There are two blood tests used in immunohematology, both of which are known as Coombs tests or antiglobulin tests. The Coombs tests are the direct and indirect ones. A direct Coombs test is used to determine whether an individual's internal red blood cells contain abnormally bound antibodies, which can happen in situations like autoimmune hemolytic anaemia, infant hemolytic illness, and transfusion responses. The indirect Coombs test is employed to detect specific blood group antigens as well as screen for antibodies that may result in transfusion reactions.

If clinically significant autoantibodies are discovered in a patient, antigen typing is carried out. It is done for the corresponding antigens to determine whether the antibodies are alloantibodies or autoantibodies.

By End User

To learn one's blood type, a person often goes to a clinic or hospital. A doctor or nurse takes a blood sample in a clinic or hospital and sends it to a lab for analysis. Hospitals often have associated laboratories, and the staff working in these labs is employed by the hospital. These labs carry out both inpatient and outpatient laboratory testing. The main duties of blood banks are to collect, process, test, store, and distribute whole blood and blood products. Blood is donated annually in the US, says the American National Red Cross. Once blood has been donated, a number of conventional tests, including ABO grouping and Rh type, are performed in the lab. Clinical laboratories are independent businesses or organisations that test goods and materials in accordance with specifications. Third-party testing refers to testing conducted by unbiased laboratories. These clinical laboratories offer cutting-edge testing services and may offer hospitals and clinics without the necessary facilities a more affordable option.


By Product

  • Consumables

  • Instruments

By Technique

  • PCR-based and Microarray Technique

  • Assay-Based Techniques

  • Massively Parallel Sequencing Techniques

  • Serology

  • Other Techniques

By Test Type

  • Blood Group and Phenotype

  • Antibody Screening

  • Cross-matching Tests

  • Antibody Identification

  • Coombs Tests

  • Antigen Typing

By End User

  • Hospitals

  • Blood Banks

  • Clinical Laboratories

Blood Grouping Reagents Market Segmentation Analysis

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Given the prevalence of various chronic conditions that increase the need for blood transfusions as well as organ transplants, as well as the strong foundation of some of the most affluent competitors, North America now leads the world in the blood grouping business. Continual market growth may also be ensured by technological advancements in the healthcare field and the rising public awareness level. A large number of the manufacturers in the area are introducing new test kits and other items, or they concentrate on working with other businesses to improve the cash flow channel while also outsourcing the production process. Additionally, substantial investments in extended research projects and a team effort to advance the technology for blood grouping could boost the market position in the ensuing years. Additionally, substantial investments in extended research projects and a team effort to advance the technology for blood grouping could boost the market position in the ensuing years.

In the coming years, the blood ed to grow at the fastest rate. The increased number of injuries from trauma or accidents may be one of the main causes of the region's large market growth. Increased demand is further fueled by increased usage of blood banking servigrouping reagents market in the Asia Pacific region is anticipatces, an increase in government programmes, and growing public awareness of blood donation.


  • North America

    • USA

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

    • The Netherlands

    • Rest of Europe

  • Asia-Pacific

    • Japan

    • south Korea

    • China

    • India

    • Australia

    • Rest of Asia-Pacific

  • The Middle East & Africa

    • Israel

    • UAE

    • South Africa

    • Rest of Middle East & Africa

  • Latin America

    • Brazil

    • Argentina

    • Rest of Latin America


Major key players are Beckman Coulter, Inc, Diagast SAS, Bio-Rad Laboratories, Inc, DAY medical SA, Haemo kinesis Pty Ltd, MTC Med. Produkte GmbH, Novacyt Group, Ortho Clinical Diagnostics, Merck KGaA, Yuvraj Biobiz Incubator India Pvt, Rapid Labs Ltd. and other players.

DAY medical SA-Company Financial Analysis

Company Landscape Analysis

Blood Grouping Reagents Market Report Scope:

Report Attributes Details
Market Size in 2022 US$ 1.90 Billion
Market Size by 2030 US$ 4.11 Billion
CAGR CAGR of 10.1% From 2023 to 2030
Base Year 2022
Forecast Period 2023-2030
Historical Data 2020-2021
Report Scope & Coverage Market Size, Segments Analysis, Competitive  Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook
Key Segments • By Product (Consumables, Instruments)
• By Technique (PCR-based and Microarray Technique, Assay-Based Techniques, Massively Parallel Sequencing Techniques, Serology, Other Techniques)
• By Test Type (Blood Group and Phenotype, Antibody Screening, Cross-matching Tests, Antibody Identification, Coombs Tests, Antigen Typing)
• By End User (Hospitals, Blood Banks, Clinical Laboratories)
Regional Analysis/Coverage North America (USA, Canada, Mexico), Europe
(Germany, UK, France, Italy, Spain, Netherlands,
Rest of Europe), Asia-Pacific (Japan, South Korea,
China, India, Australia, Rest of Asia-Pacific), The
Middle East & Africa (Israel, UAE, South Africa,
Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America)
Company Profiles Beckman Coulter, Inc, Diagast SAS, Bio-Rad Laboratories, Inc, DAY medical SA, Haemo kinesis Pty Ltd, MTC Med. Produkte GmbH, Novacyt Group, Ortho Clinical Diagnostics, Merck KGaA, Yuvraj Biobiz Incubator India Pvt, Rapid Labs Ltd.
Key Drivers • The No. of Blood Donations is Increasing
• An Increase in the Number of Emergencies, Trauma Cases, and Road Accidents That Require Blood Transfusions.
RESTRAINTS • Concern about the effectiveness and precision of test kits.

Frequently Asked Questions

Ans. Blood Grouping Reagents Market Size was valued at USD 1.90 billion in 2022.

Ans. Economies in Emergence, and Types of Blood Groups Using Molecular Diagnostics are the key drivers of the Blood Grouping Reagents market

Ans. North America now leads the world in the blood grouping business. Continual market growth may also be ensured by technological advancements in the healthcare field and the rising public awareness level.

Ans. The Blood Grouping Reagents Market is growing at a CAGR of 10.1% over the forecast period 2023-2030.

Ans. Blood Grouping Reagents market is divided in four segments and they are By Product, By Technique, By Test Type, and By End User

Table of Contents

1. Introduction

1.1 Market Definition

1.2 Scope

1.3 Research Assumptions

2. Research Methodology

3. Market Dynamics

3.1 Drivers

3.2 Restraints

3.3 Opportunities

3.4 Challenges

4. Impact Analysis

4.1 COVID-19 Impact Analysis

4.2 Impact of Ukraine- Russia War

4.3 Impact of Ongoing Recession

4.3.1 Introduction

4.3.2 Impact on major economies US Canada Germany France United Kingdom China Japan South Korea Rest of the World

5. Value Chain Analysis

6. Porter’s 5 forces model

7.  PEST Analysis


8. Blood Grouping Reagents Market Segmentation, By Product

8.1 Consumables

8.2 Instruments

9. Blood Grouping Reagents Market Segmentation, By Technique

9.1 PCR-based and Microarray Technique

9.2 Assay-Based Techniques

9.3 Massively Parallel Sequencing Techniques

9.4 Serology

9.5 Other Techniques

10. Blood Grouping Reagents Market Segmentation, By Test Type

10.1 Blood Group and Phenotype

10.2 Antibody Screening

10.3 Cross-matching Tests

10.4 Antibody Identification

10.5 Coombs Tests

10.6 Antigen Typing

11. Blood Grouping Reagents Market Segmentation, By End User

11.1 Hospitals

11.2 Blood Banks

11.3 Clinical Laboratories

12. Regional Analysis

12.1 Introduction

12.2 North America

12.2.1 USA

12.2.2 Canada

12.2.3 Mexico

12.3 Europe

12.3.1 Germany

12.3.2 UK

12.3.3 France

12.3.4 Italy

12.3.5 Spain

12.3.6 The Netherlands

12.3.7 Rest of Europe

12.4 Asia-Pacific

12.4.1 Japan

12.4.2 South Korea

12.4.3 China

12.4.4 India

12.4.5 Australia

12.4.6 Rest of Asia-Pacific

12.5 The Middle East & Africa

12.5.1 Israel

12.5.2 UAE

12.5.3 South Africa

12.5.4 Rest

12.6 Latin America

12.6.1 Brazil

12.6.2 Argentina

12.6.3 Rest of Latin America

13. Company Profiles

13.1 Beckman Coulter, Inc.

13.1.1 Financial

13.1.2 Products/ Services Offered

13.1.3 SWOT Analysis

13.1.4 The SNS view

13.2 Diagast SAS

13.3 Bio-Rad Laboratories, Inc

13.4 DAY medical SA

13.5 Haemo kinesis Pty Ltd

13.6 MTC Med. Produkte GmbH

13.7 Novacyt Group

13.8 Ortho Clinical Diagnostics

13.9 Merck KGaA

13.10 Yuvraj Biobiz Incubator India Pvt

14. Competitive Landscape

14.1 Competitive Benchmark

14.2 Market Share Analysis

14.3 Recent Developments

15. Conclusion

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Secondary Research

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Primary Research

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Data Bank Validation

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