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Cell & Gene Therapy Manufacturing Services Market

Cell & Gene Therapy Manufacturing Services Market Size, Share & Segment by Type (Gene Therapy Manufacturing, Cell Therapy Manufacturing), By Scale Type (Commercial Scale Manufacturing, Pre-commercial/ R&D Scale Manufacturing), By Mode type (In-house Manufacturing, Contract Manufacturing), By Workflow type (Cell Processing, Fill & Finish Operations, Vector Production, Analytical And Quality Testing, Cell Banking, Process Development, Raw Material Testing, Others), by Regions and Global Forecast 2022-2028

Report Id: SNS/HC/1187 | May 2022 | Region: Global | 125 Pages

Report Scope & Overview:

The Cell & Gene Therapy Manufacturing Services Market Size was valued at USD 15.7 billion in 2021 and is expected to reach USD 56.7 billion by 2028, and grow at a CAGR of 7.8% over the forecast period 2022-2028.

Growing agreements and partnerships between CDMOs and pharmaceutical companies are propelling the cell and gene therapy manufacturing services market. The increasing rate of investment in new technologies and pharmaceutical research and development activities are also contributing to the expansion of the cell & gene therapy manufacturing services sector. Furthermore, as cancer and other diseases become more prevalent, the cell and gene therapy manufacturing services market is expanding.

Cell & Gene Therapy Manufacturing Services Market

Excessive operational expenses may limit the expansion of the cell and gene therapy manufacturing services business. It could raise the overall cost of the service and, to some extent, limit the potential in the cell and gene therapy manufacturing services market.

MARKET DYNAMICS:

DRIVERS

  • Cancer and Chronic Diseases are becoming more common.

  • Increase in number of investments.

  • The quantity of clinical preliminaries is expanding.

  • Regulatory Environment That Is Favorable

RESTRAINTS

  • Operational charges are high.

OPPORTUNITIES

  • Approvals for drugs and a healthy pipeline

  • Rise in number cell therapy.

CHALLENGES

  • There is a scarcity of reliable vectors for cell and gene therapy.

  • Scarcity of therapy-specific tests

IMPACT OF COVID-19

The current COVID-19 pandemic has had a favorable impact on the manufacture of cell and gene therapies. Several companies increased their vector production capacities and formed strategic partnerships to develop experimental medicines. This is in response to the urgent need for effective treatments as well as an anti-infection vaccination. Tevogen Bio, for example, teamed up with Biocentric to develop Tevogen’s COVID-19 T-Cell Therapy in March 2021.

The ratio of successful treatment to the number of clinical trials of cellular and gene-modified therapeutic products has improved in recent years in the healthcare industry. This is due to greater science and medical awareness of the safety risks associated with their use. In early 2020, there were 362 phase III clinical studies, with the number likely to rise dramatically in the future years.

By Therapy Type:

The high number of active clinical trials and the increasing number of goods entering the market are both contributing to the rise. To understand the potential of cell therapies for the treatment of various cancer indications, more than 250 clinical studies concentrating on CAR T cell treatments and other cell therapies are being examined. Furthermore, biopharma companies are seeing allogeneic CAR T cell therapy as a more attractive business strategy than current manufacturing and economic models.

By Scale Type:

This is due to a robust and rapidly expanding pipeline of cell and gene therapies around the world. More than 900 clinical trials for various cell treatments are currently conducted as of March 2020. According to the Journal of Gene Medicine, the number of gene therapy clinical studies has increased to 3,036 in 2020. This high figure reflects the rising need for manufacturing services in the development of preclinical product candidates.

By Mode Type:

The main contribution to this area is the presence of a large number of large capital businesses, as well as academic institutes with individualized patient treatment programs. Improved process troubleshooting agility, ownership of supply networks, and efficient creation of a corporate knowledge base to aid future in-house scale-up are all major elements driving the segment growth.

By Workflow type: 

The development of very well and robust technologies for cell therapy production has become increasingly critical as more medicines progress from clinical trials to regulatory approval. Process development solutions improve the quality and safety profiles of candidate programs while increasing efficiency.

COMPETITIVE LANDSCAPE

There are some of major key players: Merck KGaA, Thermo Fisher Scientific, Catalent Inc., Lonza, Takara Bio Inc., Wuxi Advanced Therapies, F. Hoffmann-La Roche Ltd, Samsung Biologics, Bluebird Bio Inc., Novartis AG, Boehringer Ingelheim, Hitachi Chemical Co., Ltd., Miltenyi Biotec, Cellular Therapeutics.

KEY MARKET SEGMENTS:

By Therapy Type

  • Gene Therapy Manufacturing

  • Cell Therapy Manufacturing

    • Non-Stem Cell Therapy

    • Stem Cell Therapy

By Scale Type

  • Commercial Scale Manufacturing

  • Pre-commercial/ R&D Scale Manufacturing

By Mode type

  • In-house Manufacturing

  • Contract Manufacturing

By Workflow type

  • Cell Processing

  • Fill & Finish Operations

  • Vector Production

  • Analytical And Quality Testing

  • Cell Banking

  • Process Development

  • Raw Material Testing

  • Others

Cell & Gene Therapy Manufacturing Services Market

REGIONAL ANALYSIS

North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa make up the cell and gene therapy production services market. North America, Europe, and Asia Pacific accounted for the highest proportion of the cell and gene therapy manufacturing services market in 2020. The rising commonness of disease and developing exploration exertion in malignant growth and undifferentiated cells are liable for a significant portion of the North American market.

REGIONAL COVERAGE:

  • North America

    • USA

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

    • The Netherlands

    • Rest of Europe

  • Asia-Pacific

    • Japan

    • south Korea

    • China

    • India

    • Australia

    • Rest of Asia-Pacific

  • The Middle East & Africa

    • Israel

    • UAE

    • South Africa

    • Rest of Middle East & Africa

  • Latin America

    • Brazil

    • Argentina

    • Rest of Latin America

 

Cell & Gene Therapy Manufacturing Services Market Report Scope:
Report Attributes Details
Market Size in 2021 US$ 15.7 Billion
Market Size by 2028 US$ 56.7 Billion
CAGR CAGR of 7.8% From 2022 to 2028
Base Year 2021
Forecast Period 2022-2028
Historical Data 2017-2020
Report Scope & Coverage Market Size, Segments Analysis, Competitive  Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook
Key Segments • By Type (Gene Therapy Manufacturing, Cell Therapy Manufacturing)
• By Scale Type (Commercial Scale Manufacturing, Pre-commercial/ R&D Scale Manufacturing)
• By Mode type (In-house Manufacturing, Contract Manufacturing)
• By Workflow type (Cell Processing, Fill & Finish Operations, Vector Production, Analytical And Quality Testing, Cell Banking, Process Development, Raw Material Testing, Others)
Regional Analysis/Coverage North America (USA, Canada, Mexico), Europe
(Germany, UK, France, Italy, Spain, Netherlands,
Rest of Europe), Asia-Pacific (Japan, South Korea,
China, India, Australia, Rest of Asia-Pacific), The
Middle East & Africa (Israel, UAE, South Africa,
Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America)
Company Profiles Merck KGaA, Thermo Fisher Scientific, Catalent Inc., Lonza, Takara Bio Inc., Wuxi Advanced Therapies, F. Hoffmann-La Roche Ltd, Samsung Biologics, Bluebird Bio Inc., Novartis AG, Boehringer Ingelheim, Hitachi Chemical Co., Ltd., Miltenyi Biotec, Cellular Therapeutics.
DRIVERS • Cancer and Chronic Diseases are becoming more common.
• Increase in number of investments.
• The quantity of clinical preliminaries is expanding.
RESTRAINTS • Operational charges are high.


Frequently Asked Questions (FAQ) :

Cell & Gene Therapy Manufacturing Services Market is expected to reach USD 56.7 billion by 2028.

North America, Europe, and the Asia Pacific accounted for the highest proportion of the cell and gene therapy manufacturing services market.

The market is divided into four segments and the segments are By Therapy Type, By Scale Type, By Mode type, and By Workflow type.

The challenges faced by Cell & Gene Therapy Manufacturing Services Market is there is a scarcity of reliable vectors for cell and gene therapy, and the Scarcity of therapy-specific tests.

key drivers of the Cell & Gene Therapy Manufacturing Services Market are an Increase in a number of investments, and the quantity of clinical preliminaries is expanding.


Table of Contents

 

1. Introduction

1.1 Market Definition

1.2 Scope

1.3 Research Assumptions

 

2. Research Methodology

 

3. Market Dynamics

3.1 Drivers

3.2 Restraints

3.3 Opportunities

3.4 Challenges

 

4. Impact Analysis

4.1 COVID 19 Impact Analysis

 

5. Value Chain Analysis

 

6. Porter’s 5 forces model

 

7.  PEST Analysis

 

8. Cell & Gene Therapy Manufacturing Services Market Segmentation, by Type

8.1 Gene Therapy Manufacturing

8.2 Cell Therapy Manufacturing

8.2.1 Non-Stem Cell Therapy

8.2.2 Stem Cell Therapy

 

9. Cell & Gene Therapy Manufacturing Services Market Segmentation, by Scale Type

9.1 Commercial Scale Manufacturing

9.2 Pre-commercial/ R&D Scale Manufacturing

 

10. Cell & Gene Therapy Manufacturing Services Market Segmentation, By Mode type

10.1 In-house Manufacturing

10.2 Contract Manufacturing

 

11. Cell & Gene Therapy Manufacturing Services Market Segmentation, By Workflow type

11.1 Cell Processing

11.2 Fill & Finish Operations

11.3 Vector Production

11.4 Analytical and Quality Testing

11.5 Cell Banking

11.6 Process Development

11.7 Raw Material Testing

11.8 Others

 

12. Regional Analysis

12.1 Introduction

12.2 North America

12.2.1 USA

12.2.2 Canada

12.2.3 Mexico

12.3Europe

12.3.1 Germany

12.3.2 UK

12.3.3 France

12.3.4 Italy

12.3.5 Spain

12.3.6 The Netherlands

12.3.7 Rest of Europe

12.4        Asia-Pacific

12.4.1 Japan

12.4.2 South Korea

12.4.3 China

12.4.4 India

12.4.5 Australia

12.4.6 Rest of Asia-Pacific

12.5        The Middle East & Africa

12.5.1 Israel

12.5.2 UAE

12.5.3 South Africa

12.5.4 Rest

12.6        Latin America

12.6.1 Brazil

12.6.2 Argentina

12.6.3 Rest of Latin America

 

13. Company Profiles

13.1 Merck KGaA

            13.1.1 Financial

13.1.2 Products/ Services Offered

13.1.3 SWOT Analysis

13.1.4 The SNS view

13.2 Thermo Fisher Scientific

13.3 Catalent Inc.

13.4 Lonza

13.5 Takara Bio Inc.

13.6 Wuxi Advanced Therapies

13.7 F. Hoffmann-La Roche Ltd

13.8 Samsung Biologics

13.9 Bluebird Bio Inc.

13.10 Novartis AG

13.11 Boehringer Ingelheim

13.12 Hitachi Chemical Co., Ltd.

13.12 Miltenyi Biotec

13.13 Cellular Therapeutics

 

14. Competitive Landscape

14.1 Competitive Benchmarking

14.2 Market Share analysis

14.3 Recent Developments

 

15. Conclusion

 

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Secondary Research

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