Report Scope & Overview:

The Ion Chromatography Market Size was valued at USD 2.75 billion in 2022, and expected to reach USD 5.49 billion by 2030, and grow at a CAGR of 9% over the forecast period 2023-2030.

For describing novel drug compounds and drug products, ion chromatography is the analytical method that is most frequently utilised in the pharmaceutical sector. It is utilised at all stages, including technique development and dose analysis. The method has recently helped to lessen the agony of sample analysis.

Ion Chromatography Market Revenue Analysis

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Ion chromatography, as well known as ion-exchange chromatography, is a method of chromatography that separates polar molecules and ions based on how closely they resemble an ion exchanger. It takes into account the electrical charge of the protein, which has both negatively and positively charged chemical groups, and uses a linearity gradient to increase salt concentration. In the past few years, ion chromatography has spread quickly over the world. The rising demand for monoclonal antibodies and the increased use of ion chromatography techniques for protein purification are primarily responsible for the market's expansion. The technique's widespread use in many industrial applications is another essential factor driving the ion chromatography market's expansion in the upcoming years.



  • Rising interest for particle chromatography in the drug business and medication examination

  • Developing food handling concerns

  • Expanding R&D financing for chromatographic methods


  • Infection risk from microorganisms during ion exchange

  • Shortage of Equipment Handling Skill Personnel


  • Monoclonal antibody purification processes increasingly employ chromatography

  • Another method for keeping track of mAb heterogeneity is ion exchange chromatography


  • Exorbitant Instrument Prices


Over the forecast period, it is expected that the increased COVID-19 prevalence will have a minor effect on market growth. Every industry has been affected by the unprecedented occurrences caused by the COVID-19 pandemic. In the beginning, the pandemic has affected a number of the pharmaceutical and R&D industries. Many research institutes stopped conducting studies during the pandemic's early stages.

Additionally, the diagnosis of COVID-19 has benefited from the use of chromatographic techniques, which denotes a beneficial effect on market expansion. An article in Eclinical Medicine discussed a study done to determine whether it would be possible to use breath analysis to differentiate between COVID-19 and other respiratory illnesses like influenza. The study examined these patients using Gas Chromatography-Ion Mobility Spectrometry (GC-IMS) and came to the conclusion that the creation and validation of this method allowed for the quick identification of COVID-19.

By Technique

The majority of the market was made up of the ion-exchange chromatography segment. Based on their affinity to ion exchangers, ions and polar molecules are separated in this procedure. This kind of chromatography relies on a reversible ion exchange between the target ions in the sample solution and the ions in the ion exchangers. There are two different types of exchangers, cationic and anionic exchangers.

The market expansion for the ion-exchange chromatography sector can be ascribed to the growing use of ion-exchange methods in the food and beverage and water industries.

Ion-exclusion chromatography is a technology for separation that may be utilised at preparative scale to separate powerful electrolytes from weak electrolytes and nonelectrolytes as well as for analytical scale for simultaneous analysis of ionic species. The method has reduced the amount of time required to analyses samples and allows for the overnight processing of several samples, which is propelling the expansion of this market sector.

When using the Reversed-Phase Liquid Chromatographic (RPLC) technique to separate organic ions and partially ionized organic analytes, Ion Pair Chromatography (IPC) is an efficient method. The market is expanding as a result of increased IPC demand and the technology's expanding applicability in sectors like pharmaceuticals.

By Application  

When compared to more traditional methods of environmental testing and monitoring, ion chromatography offers substantial benefits. The examination of anions and cations, both qualitatively and quantitatively, is the primary goal of ion chromatography and is one of its key applications in environmental analytical chemistry. For contamination and pollutants, these ions are evaluated in all kinds of water. The expansion of this market segment is being driven by the rising demand for ion chromatography for environmental testing.

The largest and fastest-growing industry segment throughout the study period was the pharmaceutical sector. Several important elements that are propelling the segment's expansion include the availability of government and corporate financing for biotechnology and pharmaceutical research as well as the booming pharmaceutical sector.

Additionally, rising R&D efforts in this sector for diseases including cancer and HIV/AIDS, as well as pharmaceutical and biotechnology companies' increased emphasis on building out their product pipelines, are some of the key drivers of market expansion.

The demand for food and water analysis is rising, and during the past few decades, new analytical techniques have been developed that are accelerating this market's expansion. Thus, the increasing use of ion chromatography methods in the food industry is promoting the growth of this market segment.

The development of this market is influenced by developments in chemical industry technology as well as the growing demand to distinguish between different chemical forms of elements.


By Technique

  • Ion-exchange Chromatography

  • Ion-exclusion Chromatography

  • Ion-pair Chromatography

By Application  

  • Environmental Testing

  • Pharmaceutical Industry

  • Food Industry

  • Chemical Industry

Ion Chromatography Market Segmentation Analysis

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According to projections, North America will dominate the worldwide ion chromatography market. There are many centers and institutes working on developing cutting-edge cures, and ion chromatography is increasingly used for applications including food testing, environmental monitoring, and others. Another element promoting market expansion in this area is the existence of regulatory standards. For instance, a non-profit, non-governmental body called the United States Pharmacopeia (USP) is active in establishing guidelines for using ion chromatography in pharmaceutical applications.

In terms of market size, Europe is anticipated to be in second place worldwide for ion chromatography. The primary driver driving market expansion is the rise in R&D spending to advance research initiatives. Because of the low price of ion chromatography equipment offered by suppliers and the high demand from customers in the pharmaceutical, biotechnology, and environmental laboratory sectors, Asia-Pacific is predicted to have the fastest rate of growth among the regions over the course of the assessment.


  • North America

    • USA

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

    • The Netherlands

    • Rest of Europe

  • Asia-Pacific

    • Japan

    • south Korea

    • China

    • India

    • Australia

    • Rest of Asia-Pacific

  • The Middle East & Africa

    • Israel

    • UAE

    • South Africa

    • Rest of Middle East & Africa

  • Latin America

    • Brazil

    • Argentina

    • Rest of Latin America


Major key players are East & West Analytical Instruments, Qingdao Luhai, Metrohm, Qingdao Shenghan Chromatograph Technology Co., Ltd, Shimadzu, Tosoh Bioscience, Nittoseiko Analytech Co., Ltd, Qingdao Puren Instrument, MembraPure GmbH, Sykam, Thermo Fisher Scientific and other players.

Qingdao Luhai-Company Financial Analysis

Ion Chromatography Market Report Scope:

Report Attributes Details
Market Size in 2022 US$ 2.75 Billion
Market Size by 2030 US$ 5.49 Billion
CAGR CAGR of 9% From 2023 to 2030
Base Year 2022
Forecast Period 2023-2030
Historical Data 2020-2021
Report Scope & Coverage Market Size, Segments Analysis, Competitive  Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook
Key Segments • By Technique (Ion-exchange Chromatography, Ion-exclusion Chromatography, Ion-pair Chromatography)
• By Application (Environmental Testing, Pharmaceutical Industry, Food Industry, Chemical Industry)
Regional Analysis/Coverage North America (USA, Canada, Mexico), Europe
(Germany, UK, France, Italy, Spain, Netherlands,
Rest of Europe), Asia-Pacific (Japan, South Korea,
China, India, Australia, Rest of Asia-Pacific), The
Middle East & Africa (Israel, UAE, South Africa,
Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America)
Company Profiles East & West Analytical Instruments, Qingdao Luhai, Metrohm, Qingdao Shenghan Chromatograph Technology Co., Ltd, Shimadzu, Tosoh Bioscience, Nittoseiko Analytech Co., Ltd, Qingdao Puren Instrument, MembraPure GmbH, Sykam, Thermo Fisher Scientific.
Key Drivers • Developing food handling concerns
• Expanding R&D financing for chromatographic methods
RESTRAINTS • Infection risk from microorganisms during ion exchange
• Shortage of Equipment Handling Skill Personnel

Frequently Asked Questions

Ans: The Ion Chromatography Market Size was valued at USD 2.75 billion in 2022.

Ans Developing food handling concerns, and Expanding R&D financing for chromatographic methods are the key drivers of the Ion Chromatography market

Ans. North America will dominate the worldwide ion chromatography market.

Ans. East & West Analytical Instruments, Qingdao Luhai, Metrohm, Qingdao Shenghan Chromatograph Technology Co., Ltd, Shimadzu, and Tosoh Bioscience are the key players of Ion Chromatography market

Ans: The Ion Chromatography Market is growing at a CAGR of  9% over the forecast period 2023-2030.

Table of Contents

1. Introduction

1.1 Market Definition

1.2 Scope

1.3 Research Assumptions

2. Research Methodology

3. Market Dynamics

3.1 Drivers

3.2 Restraints

3.3 Opportunities

3.4 Challenges

4. Impact Analysis

4.1 COVID-19 Impact Analysis

4.2 Impact of Ukraine- Russia war

4.3 Impact of ongoing Recession

4.3.1 Introduction

4.3.2 Impact on major economies US Canada Germany France United Kingdom China Japan South Korea Rest of the World

5. Value Chain Analysis

6. Porter’s 5 forces model

7.  PEST Analysis


8. Ion Chromatography Market Segmentation, By Technique

8.1 Ion-exchange Chromatography

8.2 Ion-exclusion Chromatography

8.3 Ion-pair Chromatography

9. Ion Chromatography Market Segmentation, By Application  

9.1 Environmental Testing

9.2 Pharmaceutical Industry

9.3 Food Industry

9.4 Chemical Industry

10. Regional Analysis

10.1 Introduction

10.2 North America

10.2.1 USA

10.2.2 Canada

10.2.3 Mexico

10.3 Europe

10.3.1 Germany

10.3.2 UK

10.3.3 France

10.3.4 Italy

10.3.5 Spain

10.3.6 The Netherlands

10.3.7 Rest of Europe

10.4 Asia-Pacific

10.4.1 Japan

10.4.2 South Korea

10.4.3 China

10.4.4 India

10.4.5 Australia

10.4.6 Rest of Asia-Pacific

10.5 The Middle East & Africa

10.5.1 Israel

10.5.2 UAE

10.5.3 South Africa

10.5.4 Rest

10.6 Latin America

10.6.1 Brazil

10.6.2 Argentina

10.6.3 Rest of Latin America

11. Company Profiles

11.1 East & West Analytical Instruments,

11.1.1 Financial

11.1.2 Products/ Services Offered

11.1.3 SWOT Analysis

11.1.4 The SNS view

11.2 Qingdao Luhai

11.3 Metrohm

11.4 Qingdao Shenghan Chromatograph Technology Co., Ltd

11.5 Shimadzu

11.6 Tosoh Bioscience

11.7 Nittoseiko Analytech Co., Ltd

11.8 Qingdao Puren Instrument

11.9 MembraPure GmbH

11.10 Sykam

12. Competitive Landscape

12.1 Competitive Benchmark

12.2 Market Share Analysis

12.3 Recent Developments

13. Conclusion

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The 5 steps process:

Step 1: Secondary Research:

Secondary Research or Desk Research is as the name suggests is a research process wherein, we collect data through the readily available information. In this process we use various paid and unpaid databases which our team has access to and gather data through the same. This includes examining of listed companies’ annual reports, Journals, SEC filling etc. Apart from this our team has access to various associations across the globe across different industries. Lastly, we have exchange relationships with various university as well as individual libraries.

Secondary Research

Step 2: Primary Research

When we talk about primary research, it is a type of study in which the researchers collect relevant data samples directly, rather than relying on previously collected data.  This type of research is focused on gaining content specific facts that can be sued to solve specific problems. Since the collected data is fresh and first hand therefore it makes the study more accurate and genuine.

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This step involves the triangulation of data wherein our team analyses the interview transcripts, online survey responses and observation of on filed participants. The below mentioned chart should give a better understanding of the part 1 of the primary interview.

Primary Research

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Data Bank Validation

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