Metal-Organic Framework (MOF) Market Report Scope & Overview:

The Metal-Organic Framework (MOF) Market size is valued at USD 0.63 Billion in 2025E and is projected to reach USD 3.12 Billion by 2033, growing at a CAGR of 22.28% during the forecast period 2026–2033.

The Metal-Organic Framework (MOF) Market Analysis Report provides a detailed assessment of market trends, focusing on advanced applications in gas storage, catalysis, and drug delivery. Increasing adoption across energy, pharmaceutical, and environmental industries is expected to drive robust market growth during the forecast period.

MOF production reached 4,500 tons in 2025, driven by rising demand in gas storage, catalysis, and drug delivery applications.

Market Size and Forecast:

• Market Size in 2025: USD 0.63 Billion

• Market Size by 2033: USD 3.12 Billion

• CAGR: 22.28% from 2026 to 2033

• Base Year: 2025

• Forecast Period: 2026–2033

• Historical Data: 2022–2024

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Metal-Organic Framework (MOF) Market Trends:

• Growing focus on carbon capture, hydrogen storage, and clean energy solutions is accelerating demand for advanced MOF materials.

• Rising adoption of MOFs in gas separation, catalysis, and water purification is expanding their industrial application scope.

• Increasing R&D investments and academic–industry collaborations are driving innovation in high-performance and application-specific MOFs.

• Advancements in scalable and cost-effective synthesis methods are supporting commercialization and wider market penetration.

• Expanding use of MOFs in pharmaceuticals for drug delivery and controlled release is opening new growth opportunities.

• Sustainability-driven regulations and environmental concerns are encouraging the use of MOFs in pollution control and resource-efficient technologies.

U.S. Metal-Organic Framework (MOF) Market Insights:

The U.S. Metal-Organic Framework (MOF) Market is projected to grow from USD 0.12 Billion in 2025E to USD 0.69 Billion by 2033, at a CAGR of 24.79%. Growth is driven by rising adoption of MOFs in carbon capture, hydrogen storage, gas separation, and pharmaceutical drug delivery, supported by strong R&D investments and clean energy initiatives.

Metal-Organic Framework (MOF) Market Growth Drivers:

• Accelerating demand for carbon capture, hydrogen storage, and advanced separation technologies is driving strong MOF market growth.

Accelerating demand for carbon capture, hydrogen storage, and advanced separation technologies is a major driver of Metal-Organic Framework (MOF) Market growth. As industries seek efficient solutions to reduce emissions, improve energy storage, and optimize gas purification, MOFs offer exceptional surface area and tunable properties. Their ability to enhance performance in clean energy, environmental remediation, and industrial processes is encouraging adoption across energy, chemical, and environmental sectors, significantly expanding MOF commercialization and market penetration.

MOF demand increased by 18.6% in 2025, driven by accelerating adoption in carbon capture, hydrogen storage, and advanced gas separation applications across energy and industrial sectors.

Metal-Organic Framework (MOF) Market Restraints:

• High production costs, complex synthesis processes, and limited large-scale manufacturing capabilities restrain consistent MOF market expansion.

High production costs, complex synthesis processes, and limited large-scale manufacturing capabilities significantly restrain the Metal-Organic Framework (MOF) Market. MOF synthesis often requires precise conditions, costly raw materials, and specialized equipment, making scale-up challenging. Variability in material stability, reproducibility, and performance further complicates commercialization. Additionally, the lack of standardized manufacturing protocols increases production risks and costs. These factors limit mass adoption, restrict price competitiveness, and create entry barriers for new market participants.

Metal-Organic Framework (MOF) Market Opportunities:

• Expanding adoption of MOFs in carbon capture, hydrogen storage, and next-generation energy systems creates significant market opportunities.

Expanding adoption of MOFs in carbon capture, hydrogen storage, and next-generation energy systems presents a strong opportunity for the Metal-Organic Framework (MOF) Market. Decarbonization goals and clean energy investments are accelerating demand for advanced materials with high efficiency and tunable properties. MOFs enable improved gas adsorption, storage, and separation performance. Their integration into emerging hydrogen infrastructure and carbon management technologies supports innovation, drives commercialization, and opens long-term growth avenues across energy and industrial sectors.

Energy and environmental applications accounted for 38% of new MOF development projects in 2025, driven by rising investments in carbon capture and hydrogen storage technologies.

Metal-Organic Framework (MOF) Market Segmentation Analysis:

• By Type, ZIFs held the largest market share of 34.72% in 2025, while UiOs are expected to grow at the fastest CAGR of 24.36% during 2026–2033.

• By Synthesis Method, Solvothermal processes accounted for the highest market share of 41.58% in 2025, while Mechanochemical synthesis is projected to expand at the fastest CAGR of 26.19% over the forecast period.

• By Form, Powder dominated the market with a 48.93% share in 2025, while Films are anticipated to record the fastest CAGR of 25.74% through 2026–2033.

• By Application, Gas Storage & Separation led with a 39.46% market share in 2025, while Drug Delivery is forecasted to register the fastest CAGR of 27.88% during the forecast timeline.

• By End-Use Industry, Energy & Power accounted for the largest share of 36.21% in 2025, while Pharmaceuticals are expected to witness the fastest CAGR of 28.54% from 2026–2033.

By Type, ZIFs Dominated While UiOs Are Fastest Growing:

ZIFs segment dominated the market due to their exceptional thermal stability, high surface area, and strong performance in gas separation and storage applications. Their cost-effectiveness and compatibility with industrial-scale synthesis make them widely adopted across energy and chemical industries. In 2025, ZIF-based MOF production exceeded 1,700 tons.

UiOs is the fastest growing segment, driven by superior chemical stability and increasing use in pharmaceuticals, catalysis, and harsh environmental conditions. Preferred for high-stability and long-term performance requirements. In 2025, UiO-based MOF demand reached 620 tons, reflecting rapid expansion in advanced applications.

By Synthesis Method, Solvothermal Dominated While Mechanochemical Grows Rapidly:

Solvothermal segment dominated the market due to its proven reliability, high crystallinity output, and widespread adoption in research and commercial manufacturing. This method enables precise structural control, making it ideal for producing high-performance MOFs for gas storage and catalysis. In 2025, over 2,100 tons of MOFs were synthesized using solvothermal techniques.

Mechanochemical is the fastest growing segment, gaining traction due to its low solvent usage, energy efficiency, and scalability. The method supports sustainable production, lower costs, and faster industrial-scale MOF manufacturing. In 2025, mechanochemically synthesized MOFs crossed 480 tons, driven by sustainability-focused manufacturing trends.

By Form, Powder Dominated While Films Are Fastest Growing:

Powder segment dominated the market owing to its ease of handling, high surface exposure, and suitability for bulk applications such as adsorption, catalysis, and separation processes. Powdered MOFs are widely used in industrial reactors and filtration systems. In 2025, powdered MOFs accounted for more than 2,400 tons of total production volume.

Films are the fastest growing segment, supported by rising applications in sensors, membranes, and electronic devices. Strong demand for miniaturized, high-performance materials is accelerating MOF film adoption. In 2025, MOF film usage exceeded 360 tons, reflecting growing demand in precision and miniaturized technologies.

By Application, Gas Storage & Separation Dominated While Drug Delivery Expands Rapidly:

Gas Storage and Separation segment dominated the market as industries increasingly adopt MOFs for carbon capture, hydrogen storage, and industrial gas purification. Their tunable pore structures and high adsorption capacity make them ideal for large-scale energy and environmental applications. In 2025, MOF usage for gas storage and separation surpassed 1,900 tons.

Drug Delivery is the fastest growing segment, fueled by MOFs’ controlled release capabilities and biocompatibility. Rising precision medicine adoption and targeted therapeutics are accelerating MOF-based drug delivery research. In 2025, MOF utilization in drug delivery applications reached 410 tons, driven by pharmaceutical innovation.

By End-Use Industry, Energy & Power Dominated While Pharmaceuticals Are Fastest Growing:

Energy and Power segment dominated the market due to increasing deployment in hydrogen storage, carbon capture, and clean energy infrastructure. MOFs play a vital role in improving energy efficiency and reducing emissions. In 2025, energy-sector MOF consumption exceeded 1,800 tons.

Pharmaceuticals is the fastest growing segment, supported by rising investments in advanced drug delivery systems and biomedical research. In 2025, pharmaceutical MOF consumption reached 520 tons, highlighting accelerating adoption in life science applications.

Metal-Organic Framework (MOF) Market Regional Analysis:

Asia-Pacific Metal-Organic Framework (MOF) Market Insights:

The Asia-Pacific Metal-Organic Framework (MOF) Market dominated with a market share of 40.87% in 2025, driven by strong manufacturing ecosystems, rising R&D investments, and large-scale industrial adoption. Countries including China, Japan, South Korea, and India are actively utilizing MOFs in gas separation, hydrogen storage, catalysis, and environmental applications. Growing focus on clean energy transition, emission reduction initiatives, and advanced material commercialization is strengthening regional demand, positioning Asia-Pacific as the leading and most established MOF market.

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China Metal-Organic Framework (MOF) Market Insights:

China’s Metal-Organic Framework (MOF) Market is driven by strong industrial manufacturing capabilities, rising investments in clean energy and carbon capture technologies, and robust academic research. Increasing adoption of MOFs in gas separation, hydrogen storage, and catalysis positions China as a key growth and innovation hub within the Asia-Pacific MOF market.

North America Metal-Organic Framework (MOF) Market Insights:

North America is the fastest-growing Metal-Organic Framework (MOF) Market, projected to expand at a CAGR of 25.69% during 2026–2033. Growth is driven by strong R&D investments, rapid commercialization of advanced materials, and increasing adoption of MOFs in carbon capture, hydrogen storage, and pharmaceutical drug delivery. Rising focus on clean energy transition, emission reduction initiatives, and technological innovation positions North America as a key hub for MOF development, pilot projects, and next-generation industrial applications.

U.S. Metal-Organic Framework (MOF) Market Insights:

The U.S. Metal-Organic Framework (MOF) Market is driven by strong research funding, rapid commercialization of advanced materials, and rising adoption in carbon capture, hydrogen storage, and gas separation. Increasing use of MOFs in pharmaceutical drug delivery, environmental remediation, and clean energy infrastructure strengthens the country’s dominance in the North American MOF market.

Europe Metal-Organic Framework (MOF) Market Insights:

The Europe Metal-Organic Framework (MOF) Market is growing due to rising investments in clean energy, carbon reduction initiatives, and advanced materials research. Countries including Germany, the UK, France, and Italy are key contributors, supported by strong industrial bases and academic innovation. Increasing adoption of MOFs in gas separation, catalysis, environmental remediation, and pharmaceutical applications, along with supportive sustainability regulations, reinforces Europe’s role as a significant and steadily expanding MOF market.

Germany Metal-Organic Framework (MOF) Market Insights:

Germany is a key Metal-Organic Framework (MOF) market due to strong industrial infrastructure, growing investments in clean energy, and advanced materials research. Rising adoption of MOFs in carbon capture, gas separation, catalysis, and pharmaceutical applications, combined with sustainability initiatives and technology-driven innovation, strengthens Germany’s position as a leading contributor to Europe’s MOF market.

Latin America Metal-Organic Framework (MOF) Market Insights:

The Latin America Metal-Organic Framework (MOF) Market is expected to grow with increasing adoption of clean energy technologies, carbon capture initiatives, and industrial applications in Brazil, Mexico, and Argentina. Rising investments in research, environmental remediation, and gas separation, along with expanding awareness of advanced materials, are driving regional MOF market growth.

Middle East and Africa Metal-Organic Framework (MOF) Market Insights:

The Middle East & Africa Metal-Organic Framework (MOF) Market is expanding due to rising adoption of clean energy technologies, carbon capture projects, and industrial applications. Increasing investments in advanced materials, environmental remediation, and research initiatives in Saudi Arabia, UAE, and South Africa are driving regional demand and supporting market growth.

Metal-Organic Framework (MOF) Market Competitive Landscape:

BASF SE, one of the world’s largest chemical companies, has become a leader in the MOF market by leveraging its extensive process expertise and manufacturing scale. The company produces flagship MOF products such as Basolite and the BasoTrap CCS line, tailored for gas separation and carbon capture applications. BASF’s multi‑year alliances with industrial giants and its ability to scale pilot production to commercial levels reinforce its dominance. Its integration with energy and chemical sectors accelerates adoption of MOFs in sustainability‑driven applications.

• In October 2025, BASF SE highlighted its industrial‑scale production of CALF‑20 MOFs for carbon capture and water extraction applications following recognition through the Nobel Prize in Chemistry, reinforcing commercial viability and expanding MOF offerings for sustainability projects.

Merck KGaA, a German life‑science and materials science conglomerate, holds a leading position in high‑purity MOF supply, especially for analytical, pharmaceutical, and formulation applications. Known for the MIL‑series MOFs and advanced product lines such as SyntaPure MIL‑101 and Parteck MOF‑X, Merck emphasizes stringent quality standards and precision manufacturing. Strategic investments in clean‑room production and partnerships in porous drug carrier technologies have expanded its reach in both life sciences and industrial markets, reinforcing its influence in specialized MOF segments.

• In June 2025, Merck KGaA expanded its Basolite MOF portfolio to support enhanced gas separation, adsorption, and energy applications, improving availability of customizable porous frameworks for research and industrial customers.

NuMat Technologies, Inc. is a U.S.‑based innovator focused on advanced MOF solutions, particularly aluminum‑based formulations for gas storage and separation. The company’s proprietary MOF platforms power products such as ION‑X and M‑Store canisters, enhancing safety and efficiency in semiconductor, energy, and industrial applications. Strong intellectual property, strategic collaborations with national laboratories, and targeted expansion of manufacturing capacity position NuMat at the forefront of MOF commercialization, especially in niche but high‑growth application areas.

• In October 2025, NuMat Technologies celebrated Nobel Prize recognition for MOFs and emphasized its ION‑X MOF product’s commercial use in ultra‑pure gas delivery and industrial safety, advancing adoption across semiconductor, defense, and energy applications.

Metal-Organic Framework (MOF) Market Key Players:

Some of the Metal-Organic Framework (MOF) Market Companies are: 

• BASF SE

• Merck KGaA

• NuMat Technologies, Inc.

• MOF Technologies Ltd.

• Strem Chemicals, Inc.

• Framergy, Inc.

• MOFapps

• Mosaic Materials, Inc.

• ACSYNAM

• Promethean Particles Ltd.

• NanoSaar AG

• ZeoChem AG

• Kuraray Co., Ltd.

• GS Alliance Co., Ltd.

• Sivananthan Laboratories, Inc.

• NanoResearch Elements Inc.

• Chemilyzer Ltd.

• Hangzhou Trylead Chemical Technology Co., Ltd.

• Nanoshel LLC

• Sigma-Aldrich Corporation (Merck Group)