Report Id: SNS/HC/2627 | July 2022 | Region: Global | 129 Pages
Report Scope & Overview:
The Dry Age-Related Macular Degeneration Market Size was valued at USD 10.28 billion in 2021 and is expected to reach USD 17.87 billion by 2028, and grow at a CAGR of 8.22% over the forecast period 2022-2028.
Dry macular degeneration and wet macular degeneration are the two types of age-related macular degeneration (AMD). Wet (neovascular) AMD can develop from neovascular macular degeneration, which is characterised by blood vessels developing under the retina and leaking. Dry-type occurs more commonly, while it progresses more slowly over time. In general, moist-type tends to cause a quick change in eyesight, ending in significant vision loss.
The growing elderly population and increasing prevalence of age-related macular degeneration, as well as the development of novel dry AMD treatment approaches and an increasing number of clinical trials focused on dry AMD, are driving the global expansion of the dry AMD market. Other factors, such as rising healthcare costs, are expected to support market growth. The high number of failed clinical studies for dry AMD medicines, on the other hand, may limit market growth to some extent.
Geriatric Population Growth and the Prevalence of Dry Age-Related Macular Degeneration
Comprehensive and comparable estimates of each country's health spending are a critical input for health policy and planning, and are required to achieve national and international health goals.
Several medications for AMD treatment have failed to meet FDA accuracy standards.
Such unsuccessful clinical trials and rigorous regulations for dry AMD treatments may limit market expansion in the projected term.
IMPACT OF COVID-19:
The COVID-19 pandemic has had a severe impact on the dry age-related macular degeneration AMD market, as people are unable to visit ophthalmologists, reducing the overall number of patient visits. Furthermore, due to the intimate physical nature of the work, ophthalmologists themselves are at danger. Delays in diagnosis may also have negative consequences for patients, such as the development of dry AMD to advanced wet AMD. However, specialists advise people with dry AMD to continue home monitoring and make healthy lifestyle choices. Telehealth is widely used for virtual consultations with doctors. The supply chain for vitamin and zinc supplements advised for dry AMD is also impacted.
The increasing demand for supplements to improve immunity to fight coronavirus is not being met, which may have a harmful effect on individuals with dry AMD. However, companies are ramping up production, and with COVID-19 conditions easing in various nations, a return to normalcy supply and demand is likely soon.
The different governments imposed certain COVID-19-related limitations in order to control the spread of COVID-19. Travel restrictions and stay-at-home orders produced specific limitations that impacted the laboratory staff's capacity to do their tasks and perhaps disrupted the supply chain appropriately. Other possible consequences include a delay in project delivery timeframes and the storage of samples for an extended period of time due to the delay. Fear among lab personnel, as well as a lack of professionals, may impede research progress. However, because there is less human-to-human interaction in non-clinical research, the impact is likely to be minimal.
Because of the growing number of AMD patients at this stage, early-stage age-related macular degeneration has the second largest market share. There is no visual loss in early-stage AMD, which is identified by the development of medium-sized drusen beneath the retina. Drusen (yellow pigments) are amorphous debris accumulations near the basement membrane of the retinal pigment epithelium. The appearance of multiple medium-sized drusen or at least one big drusen, as well as noncentral geographic atrophy, characterises the intermediate stage of AMD. The appearance of multiple medium-sized drusen or at least one big drusen, as well as noncentral geographic atrophy, characterises the intermediate stage of AMD. The market is divided into three age groups: those aged 75 and up, those aged 60 and up, and those aged 40 and up. The above 75 years category accounts for the majority of the market and is expected to grow at a 7.49 percent CAGR from 2021 to 2028. Adults over the age of 40 are more likely to suffer vision issues, and typical changes in the eye's focusing ability, known as presbyopia, continue to worsen with age. Due to chronic, systemic illnesses such as diabetes, a family history of glaucoma, and health issues connected to excessive cholesterol, thyroid, or depression, this age group is especially vulnerable to dry AMD. Adults over the age of 60 may begin to show indicators of age-related issues that may lead to visual loss.
AMD is becoming more common in those over the age of 60, owing to various eye problems such as cataracts, dry eye, diabetic retinopathy, and glaucoma.
Due to the increasing prevalence of AMD in persons over the age of 75, as well as other dry age-related factors, this category dominates the global dry age-related macular degeneration market by age group. In 2021, Ithada had a market share of 45.29 percent. The dry age-related macular degeneration AMD market is divided into two categories: therapy and diagnostic. Nutrition therapy and telescopic lens implant are also options for treatment. Antioxidants and others are subcategories of nutrition treatment. Vitamins, zinc, copper, omega-3 fatty acids, and other antioxidants are also classified. The diagnosis segment is divided into optical coherence tomography, fluorescein angiography, preliminary test, and others. Nutrition therapy will have the biggest market share of 90.92 percent in 2021, owing to increasing trends, numerous medications in the pipeline, and the utilisation of novel treatment modalities.
Furthermore, the rising frequency of eye problems is expected to drive the worldwide dry age-related macular degeneration market during the forecast period. OCT offers a cross-sectional image of the eye that is used to assess the thickness of the macula and fluid leaking in the retina. A machine scans the retina, producing incredibly detailed images of the retina and macula. Based on the type of diagnosis, optical coherence tomography (OCT), a type of imaging that employs light to create images, has the biggest market share.
The market is divided into oral and injectables based on route of administration. The oral route, which is mostly used to treat age-related macular degeneration, has the greatest dry age-related macular degeneration AMD market share of 64.32 percent in 2021.
The key preventive treatment that can postpone the progression of eyesight loss is nutrition therapy. Dry age-related macular degeneration is treated with zinc, copper, beta-carotenoids, and other antioxidants. Because it was used in the majority of known clinical research, this method of administration has the biggest market share.
Injectables such as intravitreal and subretinal are the most often used therapy options for dry age-related macular degeneration. The currently active clinical trials for pegcetacoplan and Zimura are among the therapeutic alternatives for dry AMD delivered via this route. Small clinical trials have revealed that stem cells have no unanticipated side effects.
Santen Pharmaceuticals Inc., Ocumension Therapeutics Co. Ltd, Iveric Bio, Eyestem Research Pvt Ltd, Allergan plc, Bausch Health, Belite Bio Inc., Kubota Vision Inc., Alimera Science Inc., Phio Pharmaceuticals Corp,Yuyang DNU Co., Ltd, Stealth Biotherapeutics Inc.
by End User
Hospitals & Clinics
Academic Research Institutes
by Age Group
Above 40 Years
Above 60 Years
Above 75 Years
by Diagnosis & Treatment
by Route of Administration
The Association for Research in Vision and Ophthalmology 2021 did a study between 2021 and 2028 and concluded that dry AMD had the highest disease burden with a 16.3 percent prevalence over the 6 years compared to wet AMD, diabetic macular edoema, diabetic retinopathy, and other indications. Furthermore, rising government initiatives and financing are boosting the dry age-related macular degeneration market in North America.
Europe has the second biggest market share due to an ageing population and a growing patient population.
Furthermore, improving government initiatives, expanding healthcare frameworks, and rising demand for technologically novel therapy are propelling the dry age-related macular degeneration market in Europe forward.
The Asia-Pacific region is the fastest-growing market for age-related macular degeneration, with numerous new firms emerging at a rapid pace. Furthermore, the increased frequency of eye ailments, rising healthcare spending, and multinational corporations expanding into developing countries and establishing operational bases are expected to boost the growth of the dry age-related macular degeneration AMD market. According to the WHO, 90 percent of all visually impaired people lived in underdeveloped Asia-Pacific countries. Furthermore, due to the rapid expansion of healthcare infrastructure in these regions and the increasing demand for improved healthcare services, India and China are key contributors to market growth.
The rest of the world is predicted to grow slowly due to inadequate access and affordability of healthcare among the population. This region is divided into three parts: the Middle East, Africa, and Latin America. The growing healthcare infrastructure and healthcare expenditure in the Middle East are driving the expansion of the dry age-related macular degeneration AMD market.
Rest of Europe
Rest of Asia-Pacific
The Middle East & Africa
Rest of Middle East & Africa
Rest of Latin America
|Market Size in 2021||US$ 10.28 Billion|
|Market Size by 2028||US$ 17.87 Billion|
|CAGR||CAGR of 8.22% From 2022 to 2028|
|Report Scope & Coverage||Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook|
|Key Segments||• by Stages (Early AMD, Intermediate AMD, Late AMD)
• by End User (Hospitals & Clinics, Diagnostic Centers, Academic Research Institutes, Others)
• by Age Group (Above 40 Years, Above 60 Years, Above 75 Years)
• by Diagnosis & Treatment (Treatment, Diagnosis)
• by Route of Administration (Oral, Injectables)
|Regional Analysis/Coverage||North America (USA, Canada, Mexico), Europe
(Germany, UK, France, Italy, Spain, Netherlands,
Rest of Europe), Asia-Pacific (Japan, South Korea,
China, India, Australia, Rest of Asia-Pacific), The
Middle East & Africa (Israel, UAE, South Africa,
Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America)
|Company Profiles||Santen Pharmaceuticals Inc., Ocumension Therapeutics Co. Ltd, Iveric Bio, Eyestem Research Pvt Ltd, Allergan plc, Bausch Health, Belite Bio Inc., Kubota Vision Inc., Alimera Science Inc., Phio Pharmaceuticals Corp,Yuyang DNU Co., Ltd, Stealth Biotherapeutics Inc.|
|Key Drivers||• Geriatric Population Growth and the Prevalence of Dry Age-Related Macular Degeneration.|
|RESTRAINTS||• Several medications for AMD treatment have failed to meet FDA accuracy standards.|
Frequently Asked Questions (FAQ) :
Table of Contents
1.1 Market Definition
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
4. Impact Analysis
4.1 COVID 19 Impact Analysis
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8.Global Dry Age-Related Macular Degeneration Market, by End User
8.1 Hospitals & Clinics
8.2 Diagnostic Centers
8.3 Academic Research Institutes
9.Global Dry Age-Related Macular Degeneration Market, by Age Group
9.1 Above 40 Years
9.2 Above 60 Years
9.3 Above 75 Years
10.Global Dry Age-Related Macular Degeneration Market, by Route of Administration
11.Global Dry Age-Related Macular Degeneration Market, by Stages
11.1 Early AMD
11.2 Intermediate AMD
11.3 Late AMD
12.Global Dry Age-Related Macular Degeneration Market, by Diagnosis & Treatment
13. Regional Analysis
13.2 North America
13.3.6 The Netherlands
13.3.7 Rest of Europe
13.4.2 South Korea
13.4.6 Rest of Asia-Pacific
13.5 The Middle East & Africa
13.5.3 South Africa
13.6 Latin America
13.6.3 Rest of Latin America
14.1 Santen Pharmaceuticals Inc.
14.1.2 Products/ Services Offered
14.1.3 SWOT Analysis
14.1.4 The SNS view
14.2 Ocumension Therapeutics Co. Ltd
14.3 Iveric Bio
14.4 Eyestem Research Pvt Ltd
14.5 Allergan plc
14.6 Bausch Health
14.7 Belite Bio Inc.
14.8 Kubota Vision Inc.
14.9 Alimera Science Inc.
14.10 Phio Pharmaceuticals Corp
15. Competitive Landscape
15.1 Competitive Benchmarking
15.2 Market Share analysis
15.3 Recent Developments
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