The Live Cell Encapsulation Market size was estimated USD 211.7 million in 2022 and is expected to reach USD 289.7 million by 2030 at a CAGR of 4.0% during the forecast period of 2023-2030.
Live cell encapsulation has been regarded as a solution to several therapeutic difficulties in the current period. The primary applications of live cell encapsulation include cell transplantation, cell-based medicinal delivery, and controlled drug delivery. The method envelopes live cells in biocompatible capsules for protection. These capsules protect living cells from immune system damage. Because of cell encapsulation, compounds of interest can be supplied for a longer period of time. Using live cell encapsulation reduces the need for surgical procedures.
DRIVERS
Increasing R&D Investments
Technological Advancement
Increasing Demand for Regenerative Medicine
Regenerative medicine is a new area that tries to repair or replace damaged or diseased tissues and organs. In regenerative medicine, live cell encapsulation is critical. Because it allows for the transfer of living cells to specific areas where they can restore damaged tissues. The regenerative medicine market's rapid expansion is generating demand for live cell encapsulation technology.
RESTRAIN
The manufacturing cost of live cell encapsulation is high
The production cost of live cell encapsulation might be relatively high due to a variety of reasons. The manufacture of capsules or microspheres necessitates specific equipment and skill, both of which can be expensive. Furthermore, the cells utilized in the encapsulation process are frequently sensitive and require careful handling and processing, which adds to the manufacturing cost. Another aspect that contributes to the expense of live cell encapsulation is the regulatory requirements that must be met to ensure the finished product's safety and efficacy. This can entail considerable testing and validation, which can be time consuming and costly.
OPPORTUNITY
Significant expenditures in research and development are being made by governments and financial institutions
The market for respiratory pathogen testing kits is being pushed by an increase in respiratory ailment rates.
CHALLENGES
Limited availability
As alternative treatment methods become more extensively used, the live cell encapsulation market is projected to be hampered by a scarcity of high-quality raw materials.
Despite Russia's war on Ukraine, with its relentless bombardment and shelling of cities, including schools, universities, and R&D institutes, despite the destruction and death, science in Ukraine remains active, and many chemists continue to work in their Ukrainian laboratories. They are currently operating in extremely tough conditions, frequently without access to grants and other critical financing and unable to obtain the reagents and supplies they require or repair war-damaged equipment. However, the collective and personal support they receive from the civilized world is critical for all of us to trust in triumph and return to normal life and scientific activity.
By Polymer Type
Natural Polymers
Alginate
Chitosan
Cellulose
Others
Synthetic Polymers
In 2022, natural polymers segment is expected to held the highest market share of 69.9% during the forecast period. Natural polymers are the preferred encapsulating material. Natural polymers are large molecular weight macromolecules generated from nature that are chosen for their biodegradability, low toxicity, biocompatibility, renewability, and adaptability. Because they are of natural origin, such as microbes, animals, and plants, they can interact with cells and tissues, displaying some qualities that the body recognizes and, as a result, are not treated as foreign bodies. As a result, natural polymers such as lipids, proteins, and polysaccharides have been used as an encapsulation for encapsulating hydrophobic or hydrophilic active substances that might be solid, liquid, or gaseous in order to transport and deliver them to the appropriate sites.
By Method
Microencapsulation
Macroencapsulation
Nanoencapsulation
In 2022, the microencapsulation segment is expected to dominate the market growth of 64.2% during the forecast period. The microencapsulation technique is the process of encapsulating a bioactive material in a particle size of 1-1000 m in diameter for sustained and controlled administration as well as protection of the encapsulated bioactive ingredient from the surrounding environment. Microencapsulation offers a number of therapeutic uses in the treatment of diseases such as tuberculosis, cancer, diabetes, rheumatoid arthritis, and respiratory tract infection. Islets of Langerhans, for example, are microencapsulated and implanted in the body for long-term therapy of diabetes or other diseases that necessitate organ transplantation.
By Application
Drug Delivery
Regenerative Medicine
Cell Transplantation
Others
In 2022, the drug delivery segment is expected to dominate the market growth of 44.7% during the forecast period. For effective medication delivery, living cell encapsulation technology is employed in the production of capsules, tablets, and parenteral dosage forms. Controllable drug delivery offers enormous potential in many diseases with a progressive course. The segment is being driven by the benefits of regulated drug administration by live cell encapsulation, such as increased therapeutic effects, reduced drug dose, less cytotoxicity, improved patient convenience, and compliance. Furthermore, throughout the projection period, the regenerative medicine category is expected to rise at a rapid CAGR.
North America held a significant market share of over 35.8% in 2022. This significant percentage can be attributable to growing private-sector funding, favorable rules, and government aid. The region is primarily focused on drug discovery research, which is pushing industry expansion. The presence of innovators and important operational players has resulted in greater product penetration in the region. For example, ViaCyte, Inc. announced the start of a phase 2 clinical investigation using encapsulated cell therapy to treat type 1 diabetic patients in February 2022.
Asia-Pacific is witness to expand fastest CAGR rate during the forecast period owing to the rapid increase can be ascribed to advancements in emerging economies such as India and China's biotechnology and pharmaceutical industries. This region's profitable expansion can also be ascribed to continuous government backing for emerging countries' pharmaceutical sectors. Furthermore, current research in the realms of cancer and infectious diseases, such as COVID-19, is likely to fuel significant growth in the region's live cell encapsulation market.
REGIONAL COVERAGE
North America
US
Canada
Mexico
Europe
Eastern Europe
Poland
Romania
Hungary
Turkey
Rest of Eastern Europe
Western Europe
Germany
France
UK
Italy
Spain
Netherlands
Switzerland
Austria
Rest of Western Europe
Asia Pacific
China
India
Japan
South Korea
Vietnam
Singapore
Australia
Rest of Asia Pacific
Middle East & Africa
Middle East
UAE
Egypt
Saudi Arabia
Qatar
Rest of Middle East
Africa
Nigeria
South Africa
Rest of Africa
Latin America
Brazil
Argentina
Colombia
Rest of Latin America
The major key players are AUSTRIANOVA, Merck KGaA, Sphere Fluidics Ltd., ViaCyte, Inc., Blacktrace Holdings Ltd. (Dolomite Microfluidics), BIO INX, Living Cell Technologies Ltd., Sigilon Therapeutics, Inc., Isogen, Diatranz Otsuka Ltd., Arsenal Biosciences, and Others.
BIO INX, in November 2022, Hydrobio INX N400, the first commercially available bioresin that supports live cell encapsulation with high-resolution biofabrication, was introduced by BIO INX.
Arsenal Biosciences, in September 2022, Arsenal Biosciences secured USD 220 million in series B funding to enhance its pipeline of therapeutic candidates and cell therapy research activities for solid tumor malignancies.
ViaCyte, Inc., in February 2021, ViaCyte, Inc. announced the start of a phase 2 clinical trial utilizing encapsulated cell therapy for the treatment of type 1 diabetic patients.
| Report Attributes | Details |
| Market Size in 2022 | US$ 211.7 Million |
| Market Size by 2030 | US$ 289.7 Million |
| CAGR | CAGR of 4.0% From 2023 to 2030 |
| Base Year | 2022 |
| Forecast Period | 2023-2030 |
| Historical Data | 2019-2021 |
| Report Scope & Coverage | Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook |
| Key Segments | • By Polymer Type (Natural Polymers, Synthetic Polymers) • By Method (Microencapsulation, Macroencapsulation, Nanoencapsulation) • By Application (Drug Delivery, Regenerative Medicine, Cell Transplantation, Others) |
| Regional Analysis/Coverage | North America (US, Canada, Mexico), Europe (Eastern Europe [Poland, Romania, Hungary, Turkey, Rest of Eastern Europe] Western Europe] Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Austria, Rest of Western Europe]), Asia Pacific (China, India, Japan, South Korea, Vietnam, Singapore, Australia, Rest of Asia Pacific), Middle East & Africa (Middle East [UAE, Egypt, Saudi Arabia, Qatar, Rest of Middle East], Africa [Nigeria, South Africa, Rest of Africa], Latin America (Brazil, Argentina, Colombia Rest of Latin America) |
| Company Profiles | AUSTRIANOVA, Merck KGaA, Sphere Fluidics Ltd., ViaCyte, Inc., Blacktrace Holdings Ltd. (Dolomite Microfluidics), BIO INX, Living Cell Technologies Ltd., Sigilon Therapeutics, Inc., Isogen, Diatranz Otsuka Ltd., Arsenal Biosciences |
| Key Drivers | • Increasing R&D Investments • Technological Advancement • Increasing Demand for Regenerative Medicine |
| Market Restrain | • The manufacturing cost of live cell encapsulation is high |
Ans: Natural polymers segment is expected to held the highest market share of 69.9% in 2022.
Ans: Live Cell Encapsulation Market is anticipated to expand by 4.0% from 2023 to 2030.
Ans: The growth rate of Live Cell Encapsulation Market is expected to grow USD 289.7 million by 2030.
Ans: Live Cell Encapsulation Market size was valued at USD 211.7 million in 2022.
Ans: Rising demand for regenerative medicine.
Table of Contents
1. Introduction
1.1 Market Definition
1.2 Scope
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
3.1 Drivers
3.2 Restraints
3.3 Opportunities
3.4 Challenges
4. Impact Analysis
4.1 Impact of the Ukraine- Russia war
4.2 Impact of ongoing Recession
4.2.1 Introduction
4.2.2 Impact on major economies
4.2.2.1 US
4.2.2.2 Canada
4.2.2.3 Germany
4.2.2.4 France
4.2.2.5 United Kingdom
4.2.2.6 China
4.2.2.7 Japan
4.2.2.8 South Korea
4.2.2.9 Rest of the World
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8. Microcarriers Market Segmentation, By Polymer Type
8.1 Natural Polymers
8.1.1 Alginate
8.1.2 Chitosan
8.1.3 Cellulose
8.1.4 Others
8.2 Synthetic Polymers
9. Microcarriers Market Segmentation, By Method
9.1 Microencapsulation
9.2 Macroencapsulation
9.3 Nanoencapsulation
10. Microcarriers Market Segmentation, By Application
10.1 Drug Delivery
10.2 Regenerative Medicine
10.3 Cell Transplantation
10.4 Others
11. Regional Analysis
11.1 Introduction
11.2 North America
11.2.1 North America Live Cell Encapsulation Market by Country
11.2.2North America Live Cell Encapsulation Market by Polymer Type
11.2.3 North America Live Cell Encapsulation Market by Method
11.2.4 North America Live Cell Encapsulation Market by Application
11.2.5 USA
11.2.5.1 USA Live Cell Encapsulation Market by Polymer Type
11.2.5.2 USA Live Cell Encapsulation Market by Method
11.2.5.3 USA Live Cell Encapsulation Market by Application
11.2.6 Canada
11.2.6.1 Canada Live Cell Encapsulation Market by Polymer Type
11.2.6.2 Canada Live Cell Encapsulation Market by Method
11.2.6.3 Canada Live Cell Encapsulation Market by Application
11.2.7 Mexico
11.2.7.1 Mexico Live Cell Encapsulation Market by Polymer Type
11.2.7.2 Mexico Live Cell Encapsulation Market by Method
11.2.7.3 Mexico Live Cell Encapsulation Market by Application
11.3 Europe
11.3.1 Eastern Europe
11.3.1.1 Eastern Europe Live Cell Encapsulation Market by Country
11.3.1.2 Eastern Europe Live Cell Encapsulation Market by Polymer Type
11.3.1.3 Eastern Europe Live Cell Encapsulation Market by Method
11.3.1.4 Eastern Europe Live Cell Encapsulation Market by Application
11.3.1.5 Poland
11.3.1.5.1 Poland Live Cell Encapsulation Market by Polymer Type
11.3.1.5.2 Poland Live Cell Encapsulation Market by Method
11.3.1.5.3 Poland Live Cell Encapsulation Market by Application
11.3.1.6 Romania
11.3.1.6.1 Romania Live Cell Encapsulation Market by Polymer Type
11.3.1.6.2 Romania Live Cell Encapsulation Market by Method
11.3.1.6.4 Romania Live Cell Encapsulation Market by Application
11.3.1.7 Turkey
11.3.1.7.1 Turkey Live Cell Encapsulation Market by Polymer Type
11.3.1.7.2 Turkey Live Cell Encapsulation Market by Method
11.3.1.7.3 Turkey Live Cell Encapsulation Market by Application
11.3.1.8 Rest of Eastern Europe
11.3.1.8.1 Rest of Eastern Europe Live Cell Encapsulation Market by Polymer Type
11.3.1.8.2 Rest of Eastern Europe Live Cell Encapsulation Market by Method
11.3.1.8.3 Rest of Eastern Europe Live Cell Encapsulation Market by Application
11.3.2 Western Europe
11.3.2.1 Western Europe Live Cell Encapsulation Market by Polymer Type
11.3.2.2 Western Europe Live Cell Encapsulation Market by Method
11.3.2.3 Western Europe Live Cell Encapsulation Market by Application
11.3.2.4 Germany
11.3.2.4.1 Germany Live Cell Encapsulation Market by Polymer Type
11.3.2.4.2 Germany Live Cell Encapsulation Market by Method
11.3.2.4.3 Germany Live Cell Encapsulation Market by Application
11.3.2.5 France
11.3.2.5.1 France Live Cell Encapsulation Market by Polymer Type
11.3.2.5.2 France Live Cell Encapsulation Market by Method
11.3.2.5.3 France Live Cell Encapsulation Market by Application
11.3.2.6 UK
11.3.2.6.1 UK Live Cell Encapsulation Market by Polymer Type
11.3.2.6.2 UK Live Cell Encapsulation Market by Method
11.3.2.6.3 UK Live Cell Encapsulation Market by Application
11.3.2.7 Italy
11.3.2.7.1 Italy Live Cell Encapsulation Market by Polymer Type
11.3.2.7.2 Italy Live Cell Encapsulation Market by Method
11.3.2.7.3 Italy Live Cell Encapsulation Market by Application
11.3.2.8 Spain
11.3.2.8.1 Spain Live Cell Encapsulation Market by Polymer Type
11.3.2.8.2 Spain Live Cell Encapsulation Market by Method
11.3.2.8.3 Spain Live Cell Encapsulation Market by Application
11.3.2.9 Netherlands
11.3.2.9.1 Netherlands Live Cell Encapsulation Market by Polymer Type
11.3.2.9.2 Netherlands Live Cell Encapsulation Market by Method
11.3.2.9.3 Netherlands Live Cell Encapsulation Market by Application
11.3.2.10 Switzerland
11.3.2.10.1 Switzerland Live Cell Encapsulation Market by Polymer Type
11.3.2.10.2 Switzerland Live Cell Encapsulation Market by Method
11.3.2.10.3 Switzerland Live Cell Encapsulation Market by Application
11.3.2.11.1 Austria
11.3.2.11.2 Austria Live Cell Encapsulation Market by Polymer Type
11.3.2.11.3 Austria Live Cell Encapsulation Market by Method
11.3.2.11.4 Austria Live Cell Encapsulation Market by Application
11.3.2.12 Rest of Western Europe
11.3.2.12.1 Rest of Western Europe Live Cell Encapsulation Market by Polymer Type
11.3.2.12.2 Rest of Western Europe Live Cell Encapsulation Market by Method
11.3.2.12.3 Rest of Western Europe Live Cell Encapsulation Market by Application
11.4 Asia-Pacific
11.4.1 Asia-Pacific Live Cell Encapsulation Market by Country
11.4.2 Asia-Pacific Live Cell Encapsulation Market by Polymer Type
11.4.3 Asia-Pacific Live Cell Encapsulation Market by Method
11.4.4 Asia-Pacific Live Cell Encapsulation Market by Application
11.4.5 China
11.4.5.1 China Live Cell Encapsulation Market by Polymer Type
11.4.5.2 China Live Cell Encapsulation Market by Application
11.4.5.3 China Live Cell Encapsulation Market by Method
11.4.6 India
11.4.6.1 India Live Cell Encapsulation Market by Polymer Type
11.4.6.2 India Live Cell Encapsulation Market by Method
11.4.6.3 India Live Cell Encapsulation Market by Application
11.4.7 Japan
11.4.7.1 Japan Live Cell Encapsulation Market by Polymer Type
11.4.7.2 Japan Live Cell Encapsulation Market by Method
11.4.7.3 Japan Live Cell Encapsulation Market by Application
11.4.8 South Korea
11.4.8.1 South Korea Live Cell Encapsulation Market by Polymer Type
11.4.8.2 South Korea Live Cell Encapsulation Market by Method
11.4.8.3 South Korea Live Cell Encapsulation Market by Application
11.4.9 Vietnam
11.4.9.1 Vietnam Live Cell Encapsulation Market by Polymer Type
11.4.9.2 Vietnam Live Cell Encapsulation Market by Method
11.4.9.3 Vietnam Live Cell Encapsulation Market by Application
11.4.10 Singapore
11.4.10.1 Singapore Live Cell Encapsulation Market by Polymer Type
11.4.10.2 Singapore Live Cell Encapsulation Market by Method
11.4.10.3 Singapore Live Cell Encapsulation Market by Application
11.4.11 Australia
11.4.11.1 Australia Live Cell Encapsulation Market by Polymer Type
11.4.11.2 Australia Live Cell Encapsulation Market by Method
11.4.11.3 Australia Live Cell Encapsulation Market by Application
11.4.12 Rest of Asia-Pacific
11.4.12.1 Rest of Asia-Pacific Live Cell Encapsulation Market by Polymer Type
11.4.12.2 Rest of Asia-Pacific Live Cell Encapsulation Market by Method
11.4.12.3 Rest of Asia-Pacific Live Cell Encapsulation Market by Application
11.5 Middle East & Africa
11.5.1 Middle East
11.5.1.1 Middle East Live Cell Encapsulation Market by Country
11.5.1.2 Middle East Live Cell Encapsulation Market by Polymer Type
11.5.1.3 Middle East Live Cell Encapsulation Market by Method
11.5.1.4 Middle East Live Cell Encapsulation Market by Application
11.5.1.5 UAE
11.5.1.5.1 UAE Live Cell Encapsulation Market by Polymer Type
11.5.1.5.2 UAE Live Cell Encapsulation Market by Method
11.5.1.5.3 UAE Live Cell Encapsulation Market by Application
11.5.1.6 Egypt
11.5.1.6.1 Egypt Live Cell Encapsulation Market by Polymer Type
11.5.1.6.2 Egypt Live Cell Encapsulation Market by Method
11.5.1.6.3 Egypt Live Cell Encapsulation Market by Application
11.5.1.7 Saudi Arabia
11.5.1.7.1 Saudi Arabia Live Cell Encapsulation Market by Polymer Type
11.5.1.7.2 Saudi Arabia Live Cell Encapsulation Market by Method
11.5.1.7.3 Saudi Arabia Live Cell Encapsulation Market by Application
11.5.1.8 Qatar
11.5.1.8.1 Qatar Live Cell Encapsulation Market by Polymer Type
11.5.1.8.2 Qatar Live Cell Encapsulation Market by Method
11.5.1.8.3 Qatar Live Cell Encapsulation Market by Application
11.5.1.9 Rest of Middle East
11.5.1.9.1 Rest of Middle East Live Cell Encapsulation Market by Polymer Type
11.5.1.9.2 Rest of Middle East Live Cell Encapsulation Market by Method
11.5.1.9.3 Rest of Middle East Live Cell Encapsulation Market by Application
11.5.2 Africa
11.5.2.1 Africa Transfusion Diagnostics Market by Country
11.5.2.2 Africa Live Cell Encapsulation Market by Polymer Type
11.5.2.3 Africa Live Cell Encapsulation Market by Method
11.5.2.4 Africa Live Cell Encapsulation Market by Application
11.5.2.5 Nigeria
11.5.2.5.1 Nigeria Live Cell Encapsulation Market by Polymer Type
11.5.2.5.2 Nigeria Live Cell Encapsulation Market by Method
11.5.2.5.3 Nigeria Live Cell Encapsulation Market by Application
11.5.2.6 South Africa
11.5.2.6.1 South Africa Live Cell Encapsulation Market by Polymer Type
11.5.2.6.2 South Africa Live Cell Encapsulation Market by Method
11.5.2.6.3 South Africa Live Cell Encapsulation Market by Application
11.5.2.7 Rest of Africa
11.5.2.7.1 Rest of Africa Live Cell Encapsulation Market by Polymer Type
11.5.2.7.2 Rest of Africa Live Cell Encapsulation Market by Method
11.5.2.7.3 Rest of Africa Live Cell Encapsulation Market by Application
11.6 Latin America
11.6.1 Latin America Live Cell Encapsulation Market by Country
11.6.2 Latin America Live Cell Encapsulation Market by Polymer Type
11.6.3 Latin America Live Cell Encapsulation Market by Method
11.6.4 Latin America Live Cell Encapsulation Market by Application
11.6.5 Brazil
11.6.5.1 Brazil Live Cell Encapsulation Market by Polymer Type
11.6.5.2 Brazil Live Cell Encapsulation Market by Method
11.6.5.3 Brazil Live Cell Encapsulation Market by Application
11.6.6 Argentina
11.6.6.1 Argentina Live Cell Encapsulation Market by Polymer Type
11.6.6.2 Argentina Live Cell Encapsulation Market by Method
11.6.6.3 Argentina Live Cell Encapsulation Market by Application
11.6.7 Colombia
11.6.7.1 Colombia Live Cell Encapsulation Market by Polymer Type
11.6.7.2 Colombia Live Cell Encapsulation Market by Method
11.6.7.3 Colombia Live Cell Encapsulation Market by Application
11.6.8 Rest of Latin America
11.6.8.1 Rest of Latin America Live Cell Encapsulation Market by Polymer Type
11.6.8.2 Rest of Latin America Live Cell Encapsulation Market by Method
11.6.8.3 Rest of Latin America Live Cell Encapsulation Market by Application
12 Company Profile
12.1 AUSTRIANOVA
12.1.1 Company Overview
12.1.2 Financial
12.1.3 Product / Services Offered
12.1.4 SWOT Analysis
12.1.5 The SNS View
12.2 Merck KGaA
12.2.1 Company Overview
12.2.2 Financials
12.2.3 Product/Services Offered
12.2.4 SWOT Analysis
12.2.5 The SNS View
12.3 Sphere Fluidics Ltd.
12.3.1 Company Overview
12.3.2 Financials
12.3.3 Product/Services Offered
12.3.4 SWOT Analysis
12.3.5 The SNS View
12.4 ViaCyte, Inc.
12.4.1 Company Overview
12.4.2 Financials
12.4.3 Product/Services Offered
12.4.4 SWOT Analysis
12.4.5 The SNS View
12.5 Blacktrace Holdings Ltd. (Dolomite Microfluidics)
12.5.1 Company Overview
12.5.2 Financials
12.5.3 Product/Services Offered
12.5.4 SWOT Analysis
12.5.5 The SNS View
12.6 BIO INX
12.6.1 Company Overview
12.6.2 Financials
12.6.3 Product/Services Offered
12.6.4 SWOT Analysis
12.6.5 The SNS View
12.7 Living Cell Technologies Ltd.
12.7.1 Company Overview
12.7.2 Financials
12.7.3 Product/Services Offered
12.7.4 SWOT Analysis
12.7.5 The SNS View
12.8 Sigilon Therapeutics, Inc.
12.8.1 Company Overview
12.8.2 Financials
12.8.3 Product/Services Offered
12.8.4 SWOT Analysis
12.8.5 The SNS View
12.9 Isogen
12.9.1 Company Overview
12.9.2 Financials
12.9.3 Product/Services Offered
12.9.4 SWOT Analysis
12.9.5 The SNS View
12.10 Diatranz Otsuka Ltd.
12.10.1 Company Overview
12.10.2 Financials
12.10.3 Product/Services Offered
12.10.4 SWOT Analysis
12.10.5 The SNS View
12.11 Arsenal Biosciences
12.11.1 Company Overview
12.11.2 Financials
12.11.3 Product/Services Offered
12.11.4 SWOT Analysis
12.11.5 The SNS View
12.11 Others
13. Competitive Landscape
13.1 Competitive Bench marking
13.2 Market Share Analysis
13.3 Recent Developments
13.3.1 Industry News
13.3.2 Company News
13.3.3 Mergers & Acquisitions
14. Use Case and Best Practices
15. Conclusion
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