REPORT SCOPE & OVERVIEW
The Immunohistochemistry Market size was estimated USD 2.4 billion in 2022 and is expected to reach USD 3.7 billion by 2030 at a CAGR of 5.9% during the forecast period of 2023-2030.
Immunohistochemistry is a microscopy technique for identifying antigens and macromolecular cellular components. It necessitates visualizing the presence and distribution of the target protein in diverse cell types, biological cycles, and even subcellular localization inside complex tissues.
The aging population will promote market revenue growth. The world's senior population is predicted to reach 1.6 billion by 2050, according to the United Nations (UN). As people age, cancer, cardiovascular disease, and neurological diseases become more common, demanding precise diagnosis and individualized care. The widespread application of immunohistochemistry techniques in the research and diagnosis of numerous diseases raises the demand for immunohistochemistry reagents and kits.
Adoption of digital pathology boosting market growth
The growing trend of automation of diagnostic laboratory operations throughout major healthcare markets, digital pathology systems are increasingly being used by healthcare practitioners all over the world. Digital immunohistochemistry (IHC) combines traditional IHC staining with digital imaging and analysis tools, allowing stained tissue slides to be converted into electronic images that can be accessed, analyzed, and stored remotely, eliminating the need for physical slides and enabling efficient collaboration among pathologists and researchers. The benefits of digital pathology application in IHC are that it eliminates physical slide handling and storage, allows for remote collaboration among pathologists for case sharing and second opinions, enables objective and standardized quantitative analysis of staining, and allows for efficient archiving and integration of digital images with other data for comprehensive analysis and research.
Availability of Alternative Technologies
Immunohistochemistry is a popular technique in pathology for identifying proteins or antigens in tissue samples. There are other advanced technologies available for diagnostic and research reasons, some of them are as follows, RNA sequencing: RNA sequencing, also known as transcriptome sequencing, is a method for evaluating gene expression that is different from immunohistochemistry (HC). It entails figuring out the sequence and quantity of RNA molecules in the cell. Researchers can get data known as the transcriptome by sequencing the RNA, which provides insights into the activity of all genes within the cell. RNA sequencing enables a thorough examination of gene expression profiles without the limitations associated with immunohistochemistry.
Increasing significance of companion diagnostics
Companion diagnostics are tests or assays that help healthcare providers in making treatment decisions for patients based on the best response to therapy. The co-development of companion diagnostics with therapeutic goods has the potential to radically modify the drug development process and commercialize drug candidates by promptly and cost-effectively producing safer medications with better therapeutic efficacy. The market for companion diagnostics has a strong development potential due to an increase in demand for high-priced specialist therapies and safer medications. The increasing importance of companion diagnostics is also giving prospects for growth in the diagnostics segment, and in turn the immunohistochemistry market.
Stringent regulatory requirements
The present FDA approval process for tissue diagnostic equipment and consumables is time-consuming and complicated. This is a significant barrier for businesses when it comes to releasing new and creative products. Some tissue diagnostic products are classified as Class III (by the FDA) and require Premarket Approval (PMA) before they may be effectively sold. PMA is the most demanding marketing application, evaluating the safety and effectiveness of products.
IMPACT OF RUSSIAN UKRAINE WAR
In response to the ongoing conflict in Ukraine, Agilent Technologies, Inc. suspended sanctions-prohibited sales, halted product shipment to Russia with the exception of diagnostics and healthcare products, and limited our in-country service to those diagnostics and healthcare customers at the beginning of March. As a result, corporations discontinued substantial operations within Russia on May 23, 2022, and as a result, they recorded an inconsequential expense connected with the cessation of operations for the three months ended April 30, 2022. For the fiscal year ending October 31, 2022, sales from Russian clients comprised a negligible portion of our total revenue.
IMPACT OF ONGOING RECESSION
Despite navigating a challenging climate typified by supply chain and logistics pressures, high inflation, and a COVID-related closure in China in 2022, we were able to generate good results. In 2022, Agilent's net revenue of $6,848 million increased by 8% over the previous fiscal year. When compared to 2021, foreign currency changes had a 4% negative impact on sales growth in 2022. Net sales increased in all business categories, geographic regions, and the majority of key end markets. Revenue in the life sciences and applied markets business climbed by 9% in 2022. Foreign currency movements had a net negative impact on sales growth of 4% points in 2022. Diagnostics and genomics revenue increased by 7% in 2022.
Slide Staining System
Tissue Processing Systems
Blocking Sera & Reagents
In 2022, Antibodies segment is expected to held the highest market share of 41.1% during the forecast period due to the antibodies are so important in illness detection and drug testing. In terms of utilization rate, monoclonal antibodies and antibody-related goods such as Fc-fusion, antibody fragments, and antibody-drug conjugates have become the dominant product class. The antibodies are used in a variety of applications, including pathology, neuropathology, and hematopathology.
In 2022, the Diagnostics segment is expected to dominate the market growth of 69.2% during the forecast period. Immunohistochemistry (IHC) tests are commonly used to diagnose a variety of chronic disorders, including cancer, cardiovascular disease, infectious disease, diabetes mellitus, autoimmune diseases, and nephrological diseases. Furthermore, the rising prevalence of chronic disorders is expected to fuel the diagnostics segment.
By End User
Hospitals & Diagnostic Laboratories
In 2022, Pharmaceutical and Biotechnology Companies segment is expected to dominate the market growth of 57.6% during the forecast period owing to the serum-free medium is one of the key drivers of bio production, it can have a significant impact on viability and cell proliferation, as well as increase protein quality and production. Furthermore, the biopharmaceutical industry is expanding rapidly, not only as a result of the introduction of new therapies, but also as a result of the development of biosimilars or generics.
North America held a significant market share growing with a CAGR of 38.4% in 2022 due to the presence of key market participants, easy availability of IHC solutions, increasing use of technologically advanced IHC equipment, and introduction of newer IHC solutions. PathAI, a U.S.-based developer of AI-powered technology for pathological applications, for example, in June 2022, demonstrated a machine learning-based quality control tool built for HER2 testing in breast cancer at the American Society of Clinical Oncology virtual scientific program 2022.
Asia-Pacific is witness to expand fastest CAGR rate during the forecast period due to the expansion of the geographic footprint of the global players in the Asian markets. Furthermore, a large patient pool in countries such as India and China provides a large number of clinical subjects to carry out IHC R&D assays, resulting in revenue growth.
Rest of Eastern Europe
Rest of Western Europe
Rest of Asia Pacific
Middle East & Africa
Rest of Middle East
Rest of Africa
Rest of Latin America
The major key players are Thermo Fisher Scientific Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, Danaher Corporation, Perkinelmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc., and Others.
Danaher Corporation (US), in April 2023, Danaher Corporation (US), through its subsidiary Leica Biosystems, has acquired FDA approval for the BOND MMR Antibody Panel for the diagnosis of colorectal cancer.
F. Hoffman-La Roche AG (Switzerland), in February 2023, F. Hoffman-La Roche AG (Switzerland) has introduced the IDH1 R132H (MRQ-67) Rabbit Monoclonal Antibody and the ATRX Rabbit Polyclonal Antibody for use in the BenchMark range of brain cancer detection instruments.
Agilent Technologies, Inc. (US), in January 2023, Agilent Technologies, Inc. (US) has entered into a collaboration agreement with Akoya Biosciences to develop chromogenic and immunofluorescent multiplex tests. These assays will be utilized to develop diagnostic immunohistochemistry solutions.
|Market Size in 2022||US$ 2.4 Billion|
|Market Size by 2030||US$ 3.7 Billion|
|CAGR||CAGR of 5.9 % From 2023 to 2030|
|Report Scope & Coverage||Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook|
|Key Segments||• By Product (Antibodies, Equipment, Reagents, Kits)
• By Application (Diagnostics, Research)
• By End User (Hospitals & Diagnostic Laboratories, Research Institutes, Others)
|Regional Analysis/Coverage||North America (US, Canada, Mexico), Europe (Eastern Europe [Poland, Romania, Hungary, Turkey, Rest of Eastern Europe] Western Europe] Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Austria, Rest of Western Europe]), Asia Pacific (China, India, Japan, South Korea, Vietnam, Singapore, Australia, Rest of Asia Pacific), Middle East & Africa (Middle East [UAE, Egypt, Saudi Arabia, Qatar, Rest of Middle East], Africa [Nigeria, South Africa, Rest of Africa], Latin America (Brazil, Argentina, Colombia Rest of Latin America)|
|Company Profiles||Thermo Fisher Scientific Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, Danaher Corporation, Perkinelmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc.|
|Key Drivers||• Adoption of digital pathology boosting market growth|
|Market Opportunity||• Increasing significance of companion diagnostics|
Ans: Immunohistochemistry Market is anticipated to expand by 5.9% from 2023 to 2030.
Ans: USD 3.7 billion is expected to grow by 2030.
Ans: Immunohistochemistry Market size was valued at USD 2.4 billion in 2022.
Ans: Increasing demand for electronics devices and Increasing interest in power electronics
Ans: Rapid technological advancements in EMC Filtration.
Table of Contents
1.1 Market Definition
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
4. Impact Analysis
4.1 Impact of the Ukraine- Russia war
4.2 Impact of ongoing Recession
4.2.2 Impact on major economies
220.127.116.11 United Kingdom
18.104.22.168 South Korea
22.214.171.124 Rest of the World
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8. Immunohistochemistry Market Segmentation, By Product
8.1.1 Primary Antibodies
8.1.2 Secondary Antibodies
8.2.1 Slide Staining System
8.2.2 Tissue Microarrays
8.2.3 Tissue Processing Systems
8.2.4 Slide Scanners
8.3.1 Histological stains
8.3.2 Blocking Sera & Reagents
8.3.3 Chromogenic Substrates
8.3.4 Fixation Reagents
8.3.5 Organic Solvents
8.3.6 Proteolytic Enzymes
8.3.8 Other Reagents
9. Immunohistochemistry Market Segmentation, By Application
10. Immunohistochemistry Market Segmentation, By End User
10.1 Hospitals & Diagnostic Laboratories
10.2 Research Institutes
10.3 Others Conventional End User
11. Regional Analysis
11.2 North America
11.2.1 North America Immunohistochemistry Market by Country
11.2.2 North America Immunohistochemistry Market by Product
11.2.3 North America Immunohistochemistry Market by Application
11.2.4 North America Immunohistochemistry Market by End User
126.96.36.199 USA Immunohistochemistry Market by Product
188.8.131.52 USA Immunohistochemistry Market by Application
184.108.40.206 USA Immunohistochemistry Market by End User
220.127.116.11 Canada Immunohistochemistry Market by Product
18.104.22.168 Canada Immunohistochemistry Market by Application
22.214.171.124 Canada Immunohistochemistry Market by End User
126.96.36.199 Mexico Immunohistochemistry Market by Product
188.8.131.52 Mexico Immunohistochemistry Market by Application
184.108.40.206 Mexico Immunohistochemistry Market by End User
11.3.1 Eastern Europe
220.127.116.11 Eastern Europe Immunohistochemistry Market by Country
18.104.22.168 Eastern Europe Immunohistochemistry Market by Product
22.214.171.124 Eastern Europe Immunohistochemistry Market by Application
126.96.36.199 Eastern Europe Immunohistochemistry Market by End User
188.8.131.52.1 Poland Immunohistochemistry Market by Product
184.108.40.206.2 Poland Immunohistochemistry Market by Application
220.127.116.11.3 Poland Immunohistochemistry Market by End User
18.104.22.168.1 Romania Immunohistochemistry Market by Product
22.214.171.124.2 Romania Immunohistochemistry Market by Application
126.96.36.199.4 Romania Immunohistochemistry Market by End User
188.8.131.52.1 Turkey Immunohistochemistry Market by Product
184.108.40.206.2 Turkey Immunohistochemistry Market by Application
220.127.116.11.3 Turkey Immunohistochemistry Market by End User
18.104.22.168 Rest of Eastern Europe
22.214.171.124.1 Rest of Eastern Europe Immunohistochemistry Market by Product
126.96.36.199.2 Rest of Eastern Europe Immunohistochemistry Market by Application
188.8.131.52.3 Rest of Eastern Europe Immunohistochemistry Market by End User
11.3.2 Western Europe
184.108.40.206 Western Europe Immunohistochemistry Market by Product
220.127.116.11 Western Europe Immunohistochemistry Market by Application
18.104.22.168 Western Europe Immunohistochemistry Market by End User
22.214.171.124.1 Germany Immunohistochemistry Market by Product
126.96.36.199.2 Germany Immunohistochemistry Market by Application
188.8.131.52.3 Germany Immunohistochemistry Market by End User
184.108.40.206.1 France Immunohistochemistry Market by Product
220.127.116.11.2 France Immunohistochemistry Market by Application
18.104.22.168.3 France Immunohistochemistry Market by End User
22.214.171.124.1 UK Immunohistochemistry Market by Product
126.96.36.199.2 UK Immunohistochemistry Market by Application
188.8.131.52.3 UK Immunohistochemistry Market by End User
184.108.40.206.1 Italy Immunohistochemistry Market by Product
220.127.116.11.2 Italy Immunohistochemistry Market by Application
18.104.22.168.3 Italy Immunohistochemistry Market by End User
22.214.171.124.1 Spain Immunohistochemistry Market by Product
126.96.36.199.2 Spain Immunohistochemistry Market by Application
188.8.131.52.3 Spain Immunohistochemistry Market by End User
184.108.40.206.1 Netherlands Immunohistochemistry Market by Product
220.127.116.11.2 Netherlands Immunohistochemistry Market by Application
18.104.22.168.3 Netherlands Immunohistochemistry Market by End User
22.214.171.124.1 Switzerland Immunohistochemistry Market by Product
126.96.36.199.2 Switzerland Immunohistochemistry Market by Application
188.8.131.52.3 Switzerland Immunohistochemistry Market by End User
184.108.40.206.2 Austria Immunohistochemistry Market by Product
220.127.116.11.3 Austria Immunohistochemistry Market by Application
18.104.22.168.4 Austria Immunohistochemistry Market by End User
22.214.171.124 Rest of Western Europe
126.96.36.199.1 Rest of Western Europe Immunohistochemistry Market by Product
188.8.131.52.2 Rest of Western Europe Immunohistochemistry Market by Application
184.108.40.206.3 Rest of Western Europe Immunohistochemistry Market by End User
11.4.1 Asia-Pacific Immunohistochemistry Market by Country
11.4.2 Asia-Pacific Immunohistochemistry Market by Product
11.4.3 Asia-Pacific Immunohistochemistry Market by Application
11.4.4 Asia-Pacific Immunohistochemistry Market by End User
220.127.116.11 China Immunohistochemistry Market by Product
18.104.22.168 China Immunohistochemistry Market by End User
22.214.171.124 China Immunohistochemistry Market by Application
126.96.36.199 India Immunohistochemistry Market by Product
188.8.131.52 India Immunohistochemistry Market by Application
184.108.40.206 India Immunohistochemistry Market by End User
220.127.116.11 Japan Immunohistochemistry Market by Product
18.104.22.168 Japan Immunohistochemistry Market by Application
22.214.171.124 Japan Immunohistochemistry Market by End User
11.4.8 South Korea
126.96.36.199 South Korea Immunohistochemistry Market by Product
188.8.131.52 South Korea Immunohistochemistry Market by Application
184.108.40.206 South Korea Immunohistochemistry Market by End User
220.127.116.11 Vietnam Immunohistochemistry Market by Product
18.104.22.168 Vietnam Immunohistochemistry Market by Application
22.214.171.124 Vietnam Immunohistochemistry Market by End User
126.96.36.199 Singapore Immunohistochemistry Market by Product
188.8.131.52 Singapore Immunohistochemistry Market by Application
184.108.40.206 Singapore Immunohistochemistry Market by End User
220.127.116.11 Australia Immunohistochemistry Market by Product
18.104.22.168 Australia Immunohistochemistry Market by Application
22.214.171.124 Australia Immunohistochemistry Market by End User
11.4.12 Rest of Asia-Pacific
126.96.36.199 Rest of Asia-Pacific Immunohistochemistry Market by Product
188.8.131.52 Rest of Asia-Pacific Immunohistochemistry Market by Application
184.108.40.206 Rest of Asia-Pacific Immunohistochemistry Market by End User
11.5 Middle East & Africa
11.5.1 Middle East
220.127.116.11 Middle East Immunohistochemistry Market by Country
18.104.22.168 Middle East Immunohistochemistry Market by Product
22.214.171.124 Middle East Immunohistochemistry Market by Application
126.96.36.199 Middle East Immunohistochemistry Market by End User
188.8.131.52.1 UAE Immunohistochemistry Market by Product
184.108.40.206.2 UAE Immunohistochemistry Market by Application
220.127.116.11.3 UAE Immunohistochemistry Market by End User
18.104.22.168.1 Egypt Immunohistochemistry Market by Product
22.214.171.124.2 Egypt Immunohistochemistry Market by Application
126.96.36.199.3 Egypt Immunohistochemistry Market by End User
188.8.131.52 Saudi Arabia
184.108.40.206.1 Saudi Arabia Immunohistochemistry Market by Product
220.127.116.11.2 Saudi Arabia Immunohistochemistry Market by Application
18.104.22.168.3 Saudi Arabia Immunohistochemistry Market by End User
22.214.171.124.1 Qatar Immunohistochemistry Market by Product
126.96.36.199.2 Qatar Immunohistochemistry Market by Application
188.8.131.52.3 Qatar Immunohistochemistry Market by End User
184.108.40.206 Rest of Middle East
220.127.116.11.1 Rest of Middle East Immunohistochemistry Market by Product
18.104.22.168.2 Rest of Middle East Immunohistochemistry Market by Application
22.214.171.124.3 Rest of Middle East Immunohistochemistry Market by End User
126.96.36.199 Africa Transfusion Diagnostics Market by Country
188.8.131.52 Africa Immunohistochemistry Market by Product
184.108.40.206 Africa Immunohistochemistry Market by Application
220.127.116.11 Africa Immunohistochemistry Market by End User
18.104.22.168.1 Nigeria Immunohistochemistry Market by Product
22.214.171.124.2 Nigeria Immunohistochemistry Market by Application
126.96.36.199.3 Nigeria Immunohistochemistry Market by End User
188.8.131.52 South Africa
184.108.40.206.1 South Africa Immunohistochemistry Market by Product
220.127.116.11.2 South Africa Immunohistochemistry Market by Application
18.104.22.168.3 South Africa Immunohistochemistry Market by End User
22.214.171.124 Rest of Africa
126.96.36.199.1 Rest of Africa Immunohistochemistry Market by Product
188.8.131.52.2 Rest of Africa Immunohistochemistry Market by Application
184.108.40.206.3 Rest of Africa Immunohistochemistry Market by End User
11.6 Latin America
11.6.1 Latin America Immunohistochemistry Market by Country
11.6.2 Latin America Immunohistochemistry Market by Product
11.6.3 Latin America Immunohistochemistry Market by Application
11.6.4 Latin America Immunohistochemistry Market by End User
220.127.116.11 Brazil Immunohistochemistry Market by Product
18.104.22.168 Brazil Immunohistochemistry Market by Application
22.214.171.124 Brazil Immunohistochemistry Market by End User
126.96.36.199 Argentina Immunohistochemistry Market by Product
188.8.131.52 Argentina Immunohistochemistry Market by Application
184.108.40.206 Argentina Immunohistochemistry Market by End User
220.127.116.11 Colombia Immunohistochemistry Market by Product
18.104.22.168 Colombia Immunohistochemistry Market by Application
22.214.171.124 Colombia Immunohistochemistry Market by End User
11.6.8 Rest of Latin America
126.96.36.199 Rest of Latin America Immunohistochemistry Market by Product
188.8.131.52 Rest of Latin America Immunohistochemistry Market by Application
184.108.40.206 Rest of Latin America Immunohistochemistry Market by End User
12. Company profile
12.1 Thermo Fisher Scientific Inc.
12.1.1 Company Overview
12.1.3 Products/ Services Offered
12.1.4 SWOT Analysis
12.1.5 The SNS View
12.2 F. Hoffmann-La Roche Ltd.
12.2.1 Company Overview
12.2.3 Product/Services Offered
12.2.4 SWOT Analysis
12.2.5 The SNS View
12.3 Merck KGaA
12.3.1 Company Overview
12.3.3 Product/Services Offered
12.3.4 SWOT Analysis
12.3.5 The SNS View
12.4 Danaher Corporation
12.4.1 Company Overview
12.4.3 Product/Services Offered
12.4.4 SWOT Analysis
12.4.5 The SNS View
12.5 Perkinelmer, Inc.
12.5.1 Company Overview
12.5.3 Product/Services Offered
12.5.4 SWOT Analysis
12.5.5 The SNS View
12.6 Bio-Rad Laboratories, Inc.
12.6.1 Company Overview
12.6.3 Product/Services Offered
12.6.4 SWOT Analysis
12.6.5 The SNS View
12.7 Cell Signaling Technology, Inc.
12.7.1 Company Overview
12.7.3 Product/Services Offered
12.7.4 SWOT Analysis
12.7.5 The SNS View
12.8 Bio SB
12.8.1 Company Overview
12.8.3 Product/Services Offered
12.8.4 SWOT Analysis
12.8.5 The SNS View
12.9 Agilent Technologies, Inc.
12.9.1 Company Overview
12.9.3 Product/Services Offered
12.9.4 SWOT Analysis
12.9.5 The SNS View
12.10 Abcam plc.
12.10.1 Company Overview
12.10.3 Product/Services Offered
12.10.4 SWOT Analysis
12.10.5 The SNS View
13. Competitive Landscape
13.1 Competitive Bench marking
13.2 Market Share Analysis
13.3 Recent Developments
13.3.1 Industry News
13.3.2 Company News
13.3.3 Mergers & Acquisitions
14. Use Case and Best Practices
An accurate research report requires proper strategizing as well as implementation. There are multiple factors involved in the completion of good and accurate research report and selecting the best methodology to compete the research is the toughest part. Since the research reports we provide play a crucial role in any company’s decision-making process, therefore we at SNS Insider always believe that we should choose the best method which gives us results closer to reality. This allows us to reach at a stage wherein we can provide our clients best and accurate investment to output ratio.
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The 5 steps process:
Step 1: Secondary Research:
Secondary Research or Desk Research is as the name suggests is a research process wherein, we collect data through the readily available information. In this process we use various paid and unpaid databases which our team has access to and gather data through the same. This includes examining of listed companies’ annual reports, Journals, SEC filling etc. Apart from this our team has access to various associations across the globe across different industries. Lastly, we have exchange relationships with various university as well as individual libraries.
Step 2: Primary Research
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We at SNS Insider have divided Primary Research into 2 parts.
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This step involves the triangulation of data wherein our team analyses the interview transcripts, online survey responses and observation of on filed participants. The below mentioned chart should give a better understanding of the part 1 of the primary interview.
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Consultants are those set of people who have at least 12 years of experience and expertise within the industry whereas Subject Matter Experts are those with at least 15 years of experience behind their back within the same space. The data with the help of two main processes i.e., FGDs (Focused Group Discussions) and IDs (Individual Discussions). This gives us a 3rd party nonbiased primary view of the market scenario making it a more dependable one while collation of the data pointers.
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