The Bone Morphogenetic Protein Market size was estimated USD 460.1 million in 2022 and is expected to reach USD 624.8 million by 2030 at a CAGR of 3.9% during the forecast period of 2023-2030.
The Food and Drug Administration (FDA) has approved Bone Morphogenetic Proteins for a variety of uses, including oral surgery and spinal fusions. Bone morphogenetic proteins are naturally occurring proteins in the human body that promote bone growth and are mostly required for bone repair. They are crucial in the development of the central nervous system.
DRIVERS
An increase in the number of spinal injuries and the elderly population
The spinal injury market is expected to develop in the next years as the prevalence of spinal injuries rises, as will the number of surgical treatments. Several manufacturers are conducting continuous research to investigate the therapeutic potential of BMP in various orthopedic illnesses such as soft tissue repair and osteoarthritis. This study is intended to improve the product's demand.
RESTRAIN
Expensive implementation
To develop and optimize BMP medicines, extensive research and development activities are required. Understanding the mechanism of action, optimizing formulations, and conducting preclinical and clinical trials all involve time and money. To conduct tests, purchase materials and equipment, and support research teams involved in such R&D operations, costly resources are required. Furthermore, healthcare providers, insurance companies, and patients may experience challenges as a result of the high cost of BMP market implementation. Because of their high prices, BMP therapies may be out of reach for those with limited financial means or poor access to medical care, limiting market expansion.
OPPORTUNITY
Rapid Technological Advancement
Technological improvements have resulted in more effective BMP therapy delivery strategies. These developments allow for more precise and regulated administration of BMPs, assuring targeted delivery to the exact location where they are required. Biocompatible scaffolds, nanoparticles, hydrogels, and microencapsulation techniques, for example, have been developed by researchers to allow for the delayed and localized release of BMPs. These delivery techniques boost BMPs' regeneration potential by simulating native tissues' supportive environment for cell growth and differentiation.
CHALLENGES
Increased expenses of procedure
Economic downturns have a wide-ranging impact on people's lives, including housing, employment, and the cost of living. It's no wonder, then, that a plethora of research has demonstrated that they have a significant negative impact on mental health. During recessions, the stress caused by unemployment and a lack of social security considerably leads to an increase in suicide rates and self-harm. This is aggravated further by the fact that mental health services in many nations are grossly underfunded. The impact of economic recessions on depression, anxiety, and trauma-related disorders and illness outcomes a scoping Review, an MDPI study, examines the global impact of recessions on mental health and wellbeing. It focuses on four mental health diseases depression, anxiety, trauma, and stress as well as two illness consequences self-harm and suicide.
By Type
Recombinant Human Bone Morphogenetic Protein-2
Recombinant Human Bone Morphogenetic Protein-7
In 2022, Recombinant Human Bone Morphogenetic Protein-2 segment is expected to held the highest market share during the forecast period. Recombinant Human Bone Morphogenetic Protein (rhBMP-2) is a bone morphogenetic protein that aids in the formation of new bones in the body. It is frequently utilized in medical operations to promote bone growth and repair. Furthermore, recombinant human bone morphogenetic protein (rhBMP-2) is created in a lab using genetic engineering. These proteins have a lot of potential for medical uses. One significant advantage of rhBMP-2 is its ability to be synthesized in huge numbers, ensuring clinical availability. It is also thought to be less prone to elicit an immunological response than other types of BMPs.
By Application
Spinal Fusion
Trauma
Reconstructive Surgery
Oral-Maxillofacial
Others
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In 2022, the spinal fusion segment is expected to dominate the market growth during the forecast period. The use of bone morphogenetic protein (BMP) in spinal fusion surgery is critical in encouraging bone growth within the body. According to research, BMP promotes fusion at a faster rate than standard bone transplant surgery. This feature is especially important since it allows surgeons to complete the treatment more quickly, resulting in a higher fusion success rate while eliminating the hazards involved with collecting grafts from the patient's hip (iliac crest autograft).
North America held a significant market share in 2022 due to North America has a modern healthcare system that includes world-class hospitals, clinics, and research organizations. This solid infrastructure facilitates the adoption and use of novel medical technologies such as Bone Morphogenetic Protein (BMP) therapies. The availability of highly skilled healthcare experts and access to cutting-edge facilities contribute significantly to the region's BMP market growth. Furthermore, North America's aging population is increasing the prevalence of age-related bone disorders and ailments. Because older people are more prone to fractures and degenerative bone problems, the requirement for BMP therapy becomes critical for their care. This demographic shift is a major driver of the BMP industry in North America.
Europe is witness to expand fastest CAGR rate during the forecast period. Osteoporosis, osteoarthritis, and spinal ailments are on the rise in Europe. This development is influenced by the aging population, inactivity, and changing nutritional choices. This has increased interest in Bone Morphogenetic Protein (BMP) treatments and other feasible regeneration approaches across Europe. Patients in the area frequently seek out BMP treatments since they have observed great results in bone repair and tissue restoration. As the prevalence of bone issues rises, various European countries have implemented beneficial healthcare policies and programs. These initiatives seek to boost the adoption of new therapies such as BMP treatments.
REGIONAL COVERAGE
North America
US
Canada
Mexico
Europe
Eastern Europe
Poland
Romania
Hungary
Turkey
Rest of Eastern Europe
Western Europe
Germany
France
UK
Italy
Spain
Netherlands
Switzerland
Austria
Rest of Western Europe
Asia Pacific
China
India
Japan
South Korea
Vietnam
Singapore
Australia
Rest of Asia Pacific
Middle East & Africa
Middle East
UAE
Egypt
Saudi Arabia
Qatar
Rest of Middle East
Africa
Nigeria
South Africa
Rest of Africa
Latin America
Brazil
Argentina
Colombia
Rest of Latin America
The major key players are Medtronic, Stryker Corporation, Merck KGaA, Prospec-Tany Technogene Ltd, Ember Therapeutics, Thermo Fisher Scientific, Akron Biotechnology LLC, Sino Biological Inc, Integra Lifesciences Holdings Corporation, Zimmer Biomet Holdings Inc., Orthofix Medical Inc., and Others.
Orthofix Medical Inc., in August 2022, Orthofix Medical Inc. signed a strategic partnership agreement with CGBio to develop and commercialize Novosis recombinant human bone morphogenetic protein-2 (rhBMP-2) bone growth materials and other future tissue regenerative solutions for the US and Canadian markets.
Orthofix Medical will develop Opus BA for cervical and lumbar spine fusion surgeries in February 2022. Opus BA acts as a scaffold, allowing bone to grow over the surface before being reabsorbed and replaced with normal bone during healing.
| Report Attributes | Details |
| Market Size in 2022 | US$ 460.1 Million |
| Market Size by 2030 | US$ 624.8 Million |
| CAGR | CAGR of 3.9 % From 2023 to 2030 |
| Base Year | 2022 |
| Forecast Period | 2023-2030 |
| Historical Data | 2019-2021 |
| Report Scope & Coverage | Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook |
| Key Segments | • By Type (Recombinant Human Bone Morphogenetic Protein-2, Recombinant Human Bone Morphogenetic Protein-7) • By Application (Spinal Fusion, Trauma, Reconstructive Surgery, Oral-Maxillofacial, Others) |
| Regional Analysis/Coverage | North America (US, Canada, Mexico), Europe (Eastern Europe [Poland, Romania, Hungary, Turkey, Rest of Eastern Europe] Western Europe] Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Austria, Rest of Western Europe]), Asia Pacific (China, India, Japan, South Korea, Vietnam, Singapore, Australia, Rest of Asia Pacific), Middle East & Africa (Middle East [UAE, Egypt, Saudi Arabia, Qatar, Rest of Middle East], Africa [Nigeria, South Africa, Rest of Africa], Latin America (Brazil, Argentina, Colombia Rest of Latin America) |
| Company Profiles | Medtronic, Stryker Corporation, Merck KGaA, Prospec-Tany Technogene Ltd, Ember Therapeutics, Thermo Fisher Scientific, Akron Biotechnology LLC, Sino Biological Inc, Integra Lifesciences Holdings Corporation, Zimmer Biomet Holdings Inc., Orthofix Medical Inc. |
| Key Drivers | • An increase in the number of spinal injuries and the elderly population |
| Market Restrain | • Expensive implementation |
Ans: Bone Morphogenetic Protein Market is anticipated to expand by 3.9% from 2023 to 2030.
Ans: Recombinant Human Bone Morphogenetic Protein-2 segment is expected to held the highest market share in 2022.
Ans: The growth rate of Bone Morphogenetic Protein Market is expected to grow USD 624.8 million by 2030.
Ans: Bone Morphogenetic Protein Market size was valued at USD 460.1 million in 2022.
Ans: Increased expenses of procedure
TABLE OF CONTENT
1. Introduction
1.1 Market Definition
1.2 Scope
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
3.1 Drivers
3.2 Restraints
3.3 Opportunities
3.4 Challenges
4. Impact Analysis
4.1 Impact of the Russia-Ukraine War
4.2 Impact of Ongoing Recession
4.2.1 Introduction
4.2.2 Impact on major economies
4.2.2.1 US
4.2.2.2 Canada
4.2.2.3 Germany
4.2.2.4 France
4.2.2.5 United Kingdom
4.2.2.6 China
4.2.2.7 Japan
4.2.2.8 South Korea
4.2.2.9 Rest of the World
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8. Bone Morphogenetic Protein Market Segmentation, By Type
8.1 Recombinant Human Bone Morphogenetic Protein-2
8.2 Recombinant Human Bone Morphogenetic Protein-7
9. Bone Morphogenetic Protein Market Segmentation, By Application
9.1 Spinal Fusion
9.2 Trauma
9.3 Reconstructive Surgery
9.4 Oral-Maxillofacial
9.5 Others
10. Regional Analysis
10.1 Introduction
10.2 North America
10.2.1 North America Bone Morphogenetic Protein Market by Country
10.2.2 North America Bone Morphogenetic Protein Market by Type
10.2.3 North America Bone Morphogenetic Protein Market by Application
10.2.4 USA
10.2.4.1 USA Bone Morphogenetic Protein Market by Type
10.2.4.2 USA Bone Morphogenetic Protein Market by Application
10.2.5 Canada
10.2.5.1 Canada Bone Morphogenetic Protein Market by Type
10.2.5.2 Canada Bone Morphogenetic Protein Market by Application
10.2.6 Mexico
10.2.6.1 Mexico Bone Morphogenetic Protein Market by Type
10.2.6.2 Mexico Bone Morphogenetic Protein Market by Application
10.3 Europe
10.3.1 Eastern Europe
10.3.1.1 Eastern Europe Bone Morphogenetic Protein Market by Country
10.3.1.2 Eastern Europe Bone Morphogenetic Protein Market by Type
10.3.1.3 Eastern Europe Bone Morphogenetic Protein Market by Application
10.3.1.4 Poland
10.3.1.4.1 Poland Bone Morphogenetic Protein Market by Type
10.3.1.4.2 Poland Bone Morphogenetic Protein Market by Application
10.3.1.5 Romania
10.3.1.5.1 Romania Bone Morphogenetic Protein Market by Type
10.3.1.5.2 Romania Bone Morphogenetic Protein Market by Application
10.3.1.6 Hungary
10.3.1.6.1 Hungary Bone Morphogenetic Protein Market by Type
10.3.1.6.2 Hungary Bone Morphogenetic Protein Market by Application
10.3.1.7 Turkey
10.3.1.7.1 Turkey Bone Morphogenetic Protein Market by Type
10.3.1.7.2 Turkey Bone Morphogenetic Protein Market by Application
10.3.1.8 Rest of Eastern Europe
10.3.1.8.1 Rest of Eastern Europe Bone Morphogenetic Protein Market by Type
10.3.1.8.2 Rest of Eastern Europe Bone Morphogenetic Protein Market by Application
10.3.2 Western Europe
10.3.2.1 Western Europe Bone Morphogenetic Protein Market by Country
10.3.2.2 Western Europe Bone Morphogenetic Protein Market by Type
10.3.2.3 Western Europe Bone Morphogenetic Protein Market by Application
10.3.2.4 Germany
10.3.2.4.1 Germany Bone Morphogenetic Protein Market by Type
10.3.2.4.2 Germany Bone Morphogenetic Protein Market by Application
10.3.2.5 France
10.3.2.5.1 France Bone Morphogenetic Protein Market by Type
10.3.2.5.2 France Bone Morphogenetic Protein Market by Application
10.3.2.6 UK
10.3.2.6.1 UK Bone Morphogenetic Protein Market by Type
10.3.2.6.2 UK Bone Morphogenetic Protein Market by Application
10.3.2.7 Italy
10.3.2.7.1 Italy Bone Morphogenetic Protein Market by Type
10.3.2.7.2 Italy Bone Morphogenetic Protein Market by Application
10.3.2.8 Spain
10.3.2.8.1 Spain Bone Morphogenetic Protein Market by Type
10.3.2.8.2 Spain Bone Morphogenetic Protein Market by Application
10.3.2.9 Netherlands
10.3.2.9.1 Netherlands Bone Morphogenetic Protein Market by Type
10.3.2.9.2 Netherlands Bone Morphogenetic Protein Market by Application
10.3.2.10 Switzerland
10.3.2.10.1 Switzerland Bone Morphogenetic Protein Market by Type
10.3.2.10.2 Switzerland Bone Morphogenetic Protein Market by Application
10.3.2.11 Austria
10.3.2.11.1 Austria Bone Morphogenetic Protein Market by Type
10.3.2.11.2 Austria Bone Morphogenetic Protein Market by Application
10.3.2.12 Rest of Western Europe
10.3.2.12.1 Rest of Western Europe Bone Morphogenetic Protein Market by Type
10.3.2.12.2 Rest of Western Europe Bone Morphogenetic Protein Market by Application
10.4 Asia-Pacific
10.4.1 Asia Pacific Bone Morphogenetic Protein Market by Country
10.4.2 Asia Pacific Bone Morphogenetic Protein Market by Type
10.4.3 Asia Pacific Bone Morphogenetic Protein Market by Application
10.4.4 China
10.4.4.1 China Bone Morphogenetic Protein Market by Type
10.4.4.2 China Bone Morphogenetic Protein Market by Application
10.4.5 India
10.4.5.1 India Bone Morphogenetic Protein Market by Type
10.4.5.2 India Bone Morphogenetic Protein Market by Application
10.4.6 Japan
10.4.6.1 Japan Bone Morphogenetic Protein Market by Type
10.4.6.2 Japan Bone Morphogenetic Protein Market by Application
10.4.7 South Korea
10.4.7.1 South Korea Bone Morphogenetic Protein Market by Type
10.4.7.2 South Korea Bone Morphogenetic Protein Market by Application
10.4.8 Vietnam
10.4.8.1 Vietnam Bone Morphogenetic Protein Market by Type
10.4.8.2 Vietnam Bone Morphogenetic Protein Market by Application
10.4.9 Singapore
10.4.9.1 Singapore Bone Morphogenetic Protein Market by Type
10.4.9.2 Singapore Bone Morphogenetic Protein Market by Application
10.4.10 Australia
10.4.10.1 Australia Bone Morphogenetic Protein Market by Type
10.4.10.2 Australia Bone Morphogenetic Protein Market by Application
10.4.11 Rest of Asia-Pacific
10.4.11.1 Rest of Asia-Pacific Bone Morphogenetic Protein Market by Type
10.4.11.2 Rest of Asia-Pacific Bone Morphogenetic Protein Market by Application
10.5 Middle East & Africa
10.5.1 Middle East
10.5.1.1 Middle East Bone Morphogenetic Protein Market by Country
10.5.1.2 Middle East Bone Morphogenetic Protein Market by Type
10.5.1.3 Middle East Bone Morphogenetic Protein Market by Application
10.5.1.4 UAE
10.5.1.4.1 UAE Bone Morphogenetic Protein Market by Type
10.5.1.4.2 UAE Bone Morphogenetic Protein Market by Application
10.5.1.5 Egypt
10.5.1.5.1 Egypt Bone Morphogenetic Protein Market by Type
10.5.1.5.2 Egypt Bone Morphogenetic Protein Market by Application
10.5.1.6 Saudi Arabia
10.5.1.6.1 Saudi Arabia Bone Morphogenetic Protein Market by Type
10.5.1.6.2 Saudi Arabia Bone Morphogenetic Protein Market by Application
10.5.1.7 Qatar
10.5.1.7.1 Qatar Bone Morphogenetic Protein Market by Type
10.5.1.7.2 Qatar Bone Morphogenetic Protein Market by Application
10.5.1.8 Rest of Middle East
10.5.1.8.1 Rest of Middle East Bone Morphogenetic Protein Market by Type
10.5.1.8.2 Rest of Middle East Bone Morphogenetic Protein Market by Application
10.5.2 Africa
10.5.2.1 Africa Bone Morphogenetic Protein Market by Country
10.5.2.2 Africa Bone Morphogenetic Protein Market by Type
10.5.2.3 Africa Bone Morphogenetic Protein Market by Application
10.5.2.4 Nigeria
10.5.2.4.1 Nigeria Bone Morphogenetic Protein Market by Type
10.5.2.4.2 Nigeria Bone Morphogenetic Protein Market by Application
10.5.2.5 South Africa
10.5.2.5.1 South Africa Bone Morphogenetic Protein Market by Type
10.5.2.5.2 South Africa Bone Morphogenetic Protein Market by Application
10.5.2.6 Rest of Africa
10.5.2.6.1 Rest of Africa Bone Morphogenetic Protein Market by Type
10.5.2.6.2 Rest of Africa Bone Morphogenetic Protein Market by Application
10.6 Latin America
10.6.1 Latin America Bone Morphogenetic Protein Market by Country
10.6.2 Latin America Bone Morphogenetic Protein Market by Type
10.6.3 Latin America Bone Morphogenetic Protein Market by Application
10.6.4 Brazil
10.6.4.1 Brazil Bone Morphogenetic Protein Market by Type
10.6.4.2 Brazil Bone Morphogenetic Protein Market by Application
10.6.5 Argentina
10.6.5.1 Argentina Bone Morphogenetic Protein Market by Type
10.6.5.2 Argentina Bone Morphogenetic Protein Market by Application
10.6.6 Colombia
10.6.6.1 Colombia Bone Morphogenetic Protein Market by Type
10.6.6.2 Colombia Bone Morphogenetic Protein Market by Application
10.6.7 Rest of Latin America
10.6.7.1 Rest of Latin America Bone Morphogenetic Protein Market by Type
10.6.7.2 Rest of Latin America Bone Morphogenetic Protein Market by Application
11. Company Profile
11.1 Medtronic
11.1.1 Company Overview
11.1.2 Financials
11.1.3 Product/Services Offered
11.1.4 SWOT Analysis
11.1.5 The SNS View
11.2 Stryker Corporation
11.2.1 Company Overview
11.2.2 Financials
11.2.3 Product/Services Offered
11.2.4 SWOT Analysis
11.2.5 The SNS View
11.3 Merck KGaA
11.3.1 Company Overview
11.3.2 Financials
11.3.3 Product/Services Offered
11.3.4 SWOT Analysis
11.3.5 The SNS View
11.4 Prospec-Tany Technogene Ltd
11.4 Company Overview
11.4.2 Financials
11.4.3 Product/Services Offered
11.4.4 SWOT Analysis
11.4.5 The SNS View
11.5 Ember Therapeutics
11.5.1 Company Overview
11.5.2 Financials
11.5.3 Product/Services Offered
11.5.4 SWOT Analysis
11.5.5 The SNS View
11.6 Thermo Fisher Scientific
11.6.1 Company Overview
11.6.2 Financials
11.6.3 Product/Services Offered
11.6.4 SWOT Analysis
11.6.5 The SNS View
11.7 Akron Biotechnology LLC
11.7.1 Company Overview
11.7.2 Financials
11.7.3 Product/Services Offered
11.7.4 SWOT Analysis
11.7.5 The SNS View
11.8 Sino Biological Inc
11.8.1 Company Overview
11.8.2 Financials
11.8.3 Product/Services Offered
11.8.4 SWOT Analysis
11.8.5 The SNS View
11.9 Integra Lifesciences Holdings Corporation
11.9.1 Company Overview
11.9.2 Financials
11.9.3 Product/Services Offered
11.9.4 SWOT Analysis
11.9.5 The SNS View
11.10 Zimmer Biomet Holdings Inc.
11.10.1 Company Overview
11.10.2 Financials
11.10.3 Product/Services Offered
11.10.4 SWOT Analysis
11.10.5 The SNS View
11.11 Orthofix Medical Inc.
11.11.1 Company Overview
11.11.2 Financials
11.11.3 Product/Services Offered
11.11.4 SWOT Analysis
11.11.5 The SNS View
12. Competitive Landscape
12.1 Competitive Bench marking
12.2 Market Share Analysis
12.3 Recent Developments
12.3.1 Industry News
12.3.2 Company News
12.3.3 Mergers & Acquisitions
13. USE Cases and Best Practices
14. Conclusion
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