REPORT SCOPE & OVERVIEW
Heparin Market was estimated at USD 7.5 billion in 2022 and is poised to reach at 9.20 billion in 2030 anticipated to expand at a compound annual growth rate approx. CAGR of 2.6% for the forecast period of 2023-2030.
The market is expected to be driven by the rising frequency of illnesses including renal impairment, coronary artery disease, and venous thromboembolism. The CDC estimates that by 2022, 900,000 Americans a year might be impacted by venous thromboembolism, which could cause 10% to 30% of patients to pass away within a month of diagnosis. Anticoagulants are expected to be in high demand, which will expand the market. Additionally, growing health care costs and government-sponsored programmes are some of the main drivers projected to fuel market expansion. One of the main factors influencing the overall market is thought to be the rising prevalence of chronic diseases such cardiovascular disorders, deep vein thrombosis, pulmonary embolism, and renal diseases. Non-communicable illnesses including coronary artery disease (CAD), hypertension, and diabetes are more common due to factors like inactivity, excessive drinking and smoking, poor eating habits, and changing lifestyles. The Korea Biomedical Review estimates that 13.8% of people over 30 have diabetes in 2020. Patients with diabetes are more likely to have blood clotting, which can result in heart disease and renal problems. Heparin's usage to treat these illnesses is anticipated to fuel market expansion.
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MARKET DYNAMICS
DRIVERS
Rising Cardiovascular Disease Prevalence & Expanding Surgical Techniques.
Elderly Population & Growing Knowledge of Thrombotic Disorders.
Globally, cardiovascular disorders such arterial thrombosis, pulmonary embolism, and deep vein thrombosis are on the rise. The demand for heparin is influenced by the fact that heparin is a commonly prescribed anticoagulant for the prevention and treatment of various disorders. The need for heparin as a preventative precaution against blood clots before and after surgery is driven by the increase in surgical procedures such as orthopedic, cardiovascular, and general operations. The prevalence of blood coagulation disorders and associated illnesses is increased in the elderly population. Heparin demand is anticipated to rise as the world's population continues to age.
RESTRAIN
Side Effects and Adverse Reactions.
Regulatory Challenges Due to Patent Expirations.
Bleeding, heparin-induced thrombocytopenia (HIT), and hypersensitivity responses are only a few of the unfavorable reactions and side effects that heparin may produce. Heparin use may be constrained by worries about these side effects, particularly in high-risk individuals. Some heparin products' patents have expired or are about to expire, which has allowed for the arrival of generic substitutes. This increases market competition and might have an effect on branded heparin product revenue potential. Because heparin is made from mostly porcine and bovine sources, it might be difficult to guarantee the consistency, quality, and safety of the final product. Regulations pertaining to sourcing and production standards may be onerous, which would limit market accessibility.
OPPORTUNITY
Low-Molecular-Weight Heparin (LMWH) is in greater demand.
Expanding Use of Biosimilars in Emerging Markets with Increasing Adoption.
Due to its increased safety and efficacy in comparison to unfractionated heparin, LMWH, a form of heparin with superior pharmacokinetic characteristics, is becoming more well-known. The heparin market's producers and suppliers have a chance due to the rising demand for LMWH. Heparin biosimilars are now available, providing affordable substitutes and fostering market expansion. Due to their equivalent effectiveness and safety characteristics, biosimilars are anticipated to gain popularity. Emerging economies like India, China, and Brazil offer the heparin industry substantial development potential. Players in the market have potential to increase their presence due to the growing patient population, developing healthcare infrastructure, and rising healthcare costs in these areas.
CHALLENGES
Competition from novel oral anticoagulants (NOACs) and supply chain vulnerabilities provide a risk of contamination.
There are continual difficulties in ensuring the safety and purity of heparin products, especially those made from animal sources. Strict quality control procedures and effective supply chain management are required due to the danger of contamination and supply chain vulnerabilities. Heparin faces competition from NOACs such direct oral anticoagulants (DOACs), which are readily available and gaining popularity. DOACs provide benefits such oral delivery, consistent dose, and less monitoring is needed.
IMPACT OF RUSSIAN UKRAINE WAR
As we study the reports and updated news around the world, negative effects are anticipated, particularly in Eastern Europe, the European Union, Eastern & Central Asia, and the United States. This claim has significantly disrupted trade dynamics and had a negative impact on people's lives and means of subsistence. It is anticipated that the continued conflict and unpredictability in Eastern Europe would negatively affect Ukraine and have severe, long-lasting impacts on Russia. In light of the most recent information on the war and the world's responses, the paper examines the implications for demand-supply balances, pressure on pricing variations, influence on import/export and trade, and short-term suggestions to the global heparin market. More details are comprised in the final report.
IMPACT OF ONGOING RECESSION
Heparin, a highly sulphated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. It can also be used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machine. Most of the Heparin product is existed in a form of Heparin Sodium or Heparin Calcium. From 2023 to 2030, the Heparin market displays a consistent and positive growth direction, indicating a favourable outlook for the industry. This growth is propelled by several key factors, including increasing consumer demand, advancements in technology, and shifting consumer preferences.
KEY MARKET SEGMENTS
By Type
Low Molecular Weight Heparin
Ultra-low Molecular Weight Heparin
Unfractionated Heparin
By Route of Administration
Intravenous
Subcutaneous
By Application
Venous Thromboembolism
Atrial Fibrillation
Renal Impairment
Coronary Artery Disease
Others
By End-use
Outpatient
Inpatient
By Source
Porcine
Bovine
Others
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REGIONAL COVERAGE:
North America
USA
Canada
Mexico
Europe
Germany
UK
France
Italy
Spain
The Netherlands
Rest of Europe
Asia-Pacific
Japan
South Korea
China
India
Australia
Rest of Asia-Pacific
The Middle East & Africa
Israel
UAE
South Africa
Rest of the Middle East & Africa
Latin America
Brazil
Argentina
Rest of Latin American
REGIONAL ANALYSES
North America:
In 2022, North America led the market and had the highest revenue share with 38.97%. This is brought on by the increase in cardiovascular diseases and accidents. Additional variables that contribute to the region's high proportion include rising healthcare spending and rising patient awareness in this area. According to the CDC, heart disease will account for 659,000 annual deaths in the United States, or 1 in every 4 fatalities, making it one of the leading causes of death in the nation by 2022.
Asia Pacific:
Over the course of the projection period, Asia Pacific is expected to see the market's quickest growth rate of 3.9%. Some of the main drivers of the expansion include the increasing elderly population, the big population with chronic diseases, and expanding economy. Additionally, Asia Pacific is the region that supplies the most API and crude heparin. This benefits regional businesses like Pharmax Lifesciences. Generic versions of medications whose patents have expired are produced locally at a reasonable price.
Key Players
The major key players are Pfizer Inc., Techdow USA Inc., Hepalink Group,LEO Pharma A/S, Dr. Reddy’s Laboratories Ltd., GlaxoSmithKline plc, Sanofi, Aspen Holdings, Fresenius SE & Co. KGaA, B. Braun Medical, Inc., Sandoz (Novartis AG), Hebei Changshan Biochemical Pharmaceutical Co, Ltd, and others.
Hepalink Group-Company Financial Analysis
RECENT DEVELOPMENT
Techdow USA Inc:
For the U.S. market, Techdow USA Inc.'s Enoxaparin sodium in pre-filled syringes was approved by the U.S. FDA in march 2023.
Hepalink Group:
Heparin sodium and enoxaparin sodium APIs were approved in India in March 2023, according to a Hepalink group announcement.
| Report Attributes | Details |
| Market Size in 2022 | US$ 7.5 Bn |
| Market Size by 2030 | US$ 9.20 Bn |
| CAGR | CAGR of 2.6% From 2023 to 2030 |
| Base Year | 2022 |
| Forecast Period | 2023-2030 |
| Historical Data | 2020-2021 |
| Report Scope & Coverage | Market Size, Segments Analysis, Competitive Landscape, Regional Analysis, DROC & SWOT Analysis, Forecast Outlook |
| Key Segments | • By Type (Low Molecular, Weight Heparin, Ultra-low Molecular Weight Heparin, Unfractionated Heparin) • By Route of Administration (Intravenous, Subcutaneous) • By Application (Venous Thromboembolism, Atrial Fibrillation, Renal Impairment, Coronary, Artery Disease, Others) • By End-use (Outpatient, Inpatient) |
| Regional Analysis/Coverage | North America (USA, Canada, Mexico), Europe (Germany, UK, France, Italy, Spain, Netherlands, Rest of Europe), Asia-Pacific (Japan, South Korea, China, India, Australia, Rest of Asia-Pacific), The Middle East & Africa (Israel, UAE, South Africa, Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America) |
| Company Profiles | Pfizer Inc., Techdow USA Inc., Hepalink Group,LEO Pharma A/S, Dr. Reddy’s Laboratories Ltd., GlaxoSmithKline plc, Sanofi, Aspen Holdings, Fresenius SE & Co. KGaA, B. Braun Medical, Inc., Sandoz (Novartis AG), Hebei Changshan Biochemical Pharmaceutical Co, Ltd, and others. |
| Key Drivers | • Rising Cardiovascular Disease Prevalence & Expanding Surgical Techniques. • Elderly Population & Growing Knowledge of Thrombotic Disorders. |
| Market Opportunities | • Low-Molecular-Weight Heparin (LMWH) is in greater demand. • Expanding Use of Biosimilars in Emerging Markets with Increasing Adoption. |
Ans: The CAGR Growth rate of Heparin Market is approx. CAGR 2.6% for the forecast period of 2023-2030.
Ans: The projected market size of Heparin Market at USD 7.5 billion in 2022 and is poised to reach at 9.20 billion in 2030.
Ans: The major key players are Pfizer Inc., Techdow USA Inc., Hepalink Group,LEO Pharma A/S, Dr. Reddy’s Laboratories Ltd., GlaxoSmithKline plc, Sanofi, Aspen Holdings, Fresenius SE & Co. KGaA, B. Braun Medical, Inc., Sandoz (Novartis AG), Hebei Changshan Biochemical Pharmaceutical Co, Ltd, and others.
Ans: In 2022, North America held a 38.97% market share for heparin. This is due to an increase in cardiovascular diseases and sports-related injuries. In addition, the region's significant market share may be ascribed to greater levels of healthcare spending, high patient awareness, and advanced healthcare infrastructure.
Ans: The rising incidence of chronic illnesses, rising need for transfusions of whole blood and blood components, rising geriatric population, and rising use of plasma in the pharmaceutical sector are key drivers propelling the growth of the heparin market.
Table of Contents
1. Introduction
1.1 Market Definition
1.2 Scope
1.3 Research Assumptions
2. Research Methodology
3. Market Dynamics
3.1 Drivers
3.2 Restraints
3.3 Opportunities
3.4 Challenges
4. Impact Analysis
4.1 Impact of Ukraine- Russia War
4.2 Impact of Ongoing Recession
4.2.1 Introduction
4.2.2 Impact on major economies
4.2.2.1 US
4.2.2.2 Canada
4.2.2.3 Germany
4.2.2.4 France
4.2.2.5 United Kingdom
4.2.2.6 China
4.2.2.7 Japan
4.2.2.8 South Korea
4.2.2.9 Rest of the World
5. Value Chain Analysis
6. Porter’s 5 forces model
7. PEST Analysis
8. Heparin Market, By Type
8.1 Low Molecular Weight Heparin
8.2 Ultra-low Molecular Weight Heparin
8.3 Unfractionated Heparin
9. Heparin Market, By Route of Administration
9.1 Intravenous
9.2 Subcutaneous
10. Heparin Market, By Application
10.1 Venous Thromboembolism
10.2 Atrial Fibrillation
10.3 Renal Impairment
10.4 coronary artery disease
10.5 Others
11. Heparin Market, By End-User
11.1 Outpatient
11.2 Inpatient
12. Heparin Market, By Source
12.1 Porcine
12.2 Bovine
12.3 Others
13. Regional Analysis
13.1 Introduction
13.2 North America
13.2.1 North America Heparin Market by Country
13.2.2North America Heparin Market by Type
13.2.3 North America Heparin Market by Route of Administration
13.2.4 North America Heparin Market by Application
13.2.5 North America Heparin Market by End-User
13.2.6 North America Heparin Market by Source
13.2.7 USA
13.2.7.1 USA Heparin Market by Type
13.2.7.2 USA Heparin Market by Route of Administration
13.2.7.3 USA Heparin Market by Application
13.2.7.4 USA Heparin Market by End-User
13.2.7.5 USA Heparin Market by Source
13.2.8 Canada
13.2.8.1 Canada Heparin Market by Type
13.2.8.2 Canada Heparin Market by Route of Administration
13.2.8.3 Canada Heparin Market by Application
13.2.8.4 Canada Heparin Market by End-User
13.2.8.5 Canada Heparin Market by Source
13.2.9 Mexico
13.2.9.1 Mexico Heparin Market by Type
13.2.9.2 Mexico Heparin Market by Route of Administration
13.2.9.3 Mexico Heparin Market by Application
13.2.9.4 Mexico Heparin Market by End-User
13.2.9.5 Mexico Heparin Market by Source
13.3 Europe
13.3.1 Europe Heparin Market by Country
1.3.3.2 Europe Heparin Market by Type
13.3.3 Europe Heparin Market by Route of Administration
13.3.4 Europe Heparin Market by Application
13.3.5 Europe Heparin Market by End-User
13.3.6 Europe Heparin Market by Source
13.3.7 Germany
13.3.7.1 Germany Heparin Market by Type
13.3.7.2 Germany Heparin Market by Route of Administration
13.3.7.3 Germany Heparin Market by Application
13.3.7.4 Germany Heparin Market by End-User
13.3.7.5 Germany Heparin Market by Source
13.3.8 UK
13.3.8.1 UK Heparin Market by Type
13.3.8.2 UK Heparin Market by Route of Administration
13.3.8.3 UK Heparin Market by Application
13.3.8.4 UK Heparin Market by End-User
13.3.8.5 UK Heparin Market by Source
13.3.9 France
13.3.9.1 France Heparin Market by Type
13.3.9.2 France Heparin Market by Route of Administration
13.3.9.3 France Heparin Market by Application
13.3.9.4 France Heparin Market by End-User
13.3.9.5 France Heparin Market by Source
13.3.10 Italy
13.3.10.1 Italy Heparin Market by Type
13.3.10.2 Italy Heparin Market by Route of Administration
13.3.10.3 Italy Heparin Market by Application
13.3.10.4 Italy Heparin Market by End-User
13.3.10.5 Italy Heparin Market by Source
13.3.11 Spain
13.3.11.1 Spain Heparin Market by Type
13.3.11.2 Spain Heparin Market by Route of Administration
13.3.11.3 Spain Heparin Market by Application
13.3.11.4 Spain Heparin Market by End-User
13.3.11.5 Spain Heparin Market by Source
13.3.12 The Netherlands
13.3.12.1 Netherlands Heparin Market by Type
13.3.12.2 Netherlands Heparin Market by Route of Administration
13.3.12.3 Netherlands Heparin Market by Application
13.3.12.4 Netherlands Heparin Market by End-User
13.3.12.5 Netherlands Heparin Market by Source
13.3.13 Rest of Europe
13.3.13.1 Rest of Europe Heparin Market by Type
13.3.13.2 Rest of Europe Heparin Market by Route of Administration
13.3.13.3 Rest of Europe Heparin Market by Application
13.3.13.4 Rest of Europe Heparin Market by End-User
13.3.13.5 Rest of Europe Heparin Market by Source
13.4 Asia-Pacific
13.4.1 Asia Pacific Heparin Market by Country
13.4.2 Asia Pacific Heparin Market by Type
13.4.3 Asia Pacific Heparin Market by Route of Administration
13.4.4Asia Pacific Heparin Market by Application
13.4.5Asia Pacific Heparin Market by End-User
13.4.6 Asia Pacific Heparin Market by Source
13.4.7 Japan
13.4.7.1 Japan Heparin Market by Type
13.4.7.2 Japan Heparin Market by Route of Administration
13.4.7.3 Japan Heparin Market by Application
13.4.7.4 Japan Heparin Market by End-User
13.4.7. 5Japan Heparin Market by Source
13.4.8South Korea
13.4.8.1 South Korea Heparin Market by Type
13.4.8.2 South Korea Heparin Market by Route of Administration
13.4.8.3 South Korea Heparin Market by Application
13.4.8.4 South Korea Heparin Market by End-User
13.4.8.5 South Korea Heparin Market by Source
13.4.9 China
13.4.9.1 China Heparin Market by Type
13.4.9.2 China Heparin Market by Route of Administration
13.4.9.3 China Heparin Market by Application
13.4.9.4 China Heparin Market by End-User
13.4.9.5 China Heparin Market by Source
13.4.10 India
13.4.10.1 India Heparin Market by Type
13.4.10.2 India Heparin Market by Route of Administration
13.4.10.3 India Heparin Market by Application
13.4.10.4 India Heparin Market by End-User
13.4.10.5 India Heparin Market by Source
13.4.11 Australia
13.4.11.1 Australia Heparin Market by Type
13.4.11.2 Australia Heparin Market by Route of Administration
13.4.11.3 Australia Heparin Market by Application
13.4.11.4 Australia Heparin Market by End-User
13.4.11.5 Australia Heparin Market by Source
13.4.12 Rest of Asia-Pacific
13.4.12.1 APAC Heparin Market by Type
13.4.12.2 APAC Heparin Market by Route of Administration
13.4.12.3 APAC Heparin Market by Application
13.4.12.4 APAC Heparin Market by End-User
13.4.12.5 APAC Heparin Market by Source
13.5 The Middle East & Africa
13.5.1 The Middle East & Africa Heparin Market by Country
13.5.2 The Middle East & Africa Heparin Market by Type
13.5.3 The Middle East & Africa Heparin Market by Route of Administration
13.5.4The Middle East & Africa Heparin Market by Application
13.5.5 The Middle East & Africa Heparin Market by End-User
13.5.6The Middle East & Africa Heparin Market by Source
13.5.7 Israel
13.5.7.1 Israel Heparin Market by Type
13.5.7.2 Israel Heparin Market by Route of Administration
13.5.7.3 Israel Heparin Market by Application
13.5.7.4 Israel Heparin Market by End-User
13.5.7.5 Israel Heparin Market by Source
13.5.8 UAE
13.5.8.1 UAE Heparin Market by Type
13.5.8.2 UAE Heparin Market by Route of Administration
13.5.8.3 UAE Heparin Market by Application
13.5.8.4 UAE Heparin Market by End-User
13.5.8.5 UAE Heparin Market by Source
13.5.9South Africa
13.5.9.1 South Africa Heparin Market by Type
13.5.9.2 South Africa Heparin Market by Route of Administration
13.5.9.3 South Africa Heparin Market by Application
13.5.9.4 South Africa Heparin Market by End-User
13.5.9.5 South Africa Heparin Market by Source
13.5.10 Rest of Middle East & Africa
13.5.10.1 Rest of Middle East & Asia Heparin Market by Type
13.5.10.2 Rest of Middle East & Asia Heparin Market by Route of Administration
13.5.10.3 Rest of Middle East & Asia Heparin Market Application
13.5.10.4 Rest of Middle East & Asia Heparin Market by End-User
13.5.10.5 Rest of Middle East & Asia Heparin Market by Source
13.6 Latin America
13.6.1 Latin America Heparin Market by Country
13.6.2 Latin America Heparin Market by Type
13.6.3 Latin America Heparin Market by Route of Administration
13.6.4 Latin America Heparin Market by Application
13.6.5 Latin America Heparin Market by End-User
13.6.6 Latin America Heparin Market by Source
13.6.7 Brazil
13.6.7.1 Brazil Heparin Market by Type
13.6.7.2 Brazil Africa Heparin Market by Route of Administration
13.6.7.3 Brazil Heparin Market by Application
13.6.7.4 Brazil Heparin Market by End-User
13.6.7.5 Brazil Heparin Market by Source
13.6.8 Argentina
13.6.8.1 Argentina Heparin Market by Type
13.6.8.2 Argentina Heparin Market by Route of Administration
13.6.8.3 Argentina Heparin Market by Application
13.6.8.4 Argentina Heparin Market by End-User
13.6.8.5 Argentina Heparin Market by Source
13.6.9 Rest of Latin America
13.6.9.1 Rest of Latin America Heparin Market by Type
13.6.9.2 Rest of Latin America Heparin Market by Route of Administration
13.6.9.3 Rest of Latin America Heparin Market by Application
13.6.9.4 Rest of Latin America Heparin Market by End-User
13.6.9.5 Rest of Latin America Heparin Market by Source
14 Company Profile
14.1 Pfizer Inc.
14.1.1 Market Overview
14.1.2 Financials
14.1.3 Product/Services/Offerings
14.1.4 SWOT Analysis
14.1.5 The SNS View
14.2 Techdow USA Inc.
14.2.1 Market Overview
14.2.2 Financials
14.2.3 Product/Services/Offerings
14.2.4 SWOT Analysis
14.2.5 The SNS View
14.3 Hepalink Group.
14.3.1 Market Overview
14.3.2 Financials
14.3.3 Product/Services/Offerings
14.3.4 SWOT Analysis
14.3.5 The SNS View
14.4 LEO Pharma A/S.
14.4.1 Market Overview
14.4.2 Financials
14.4.3 Product/Services/Offerings
14.4.4 SWOT Analysis
14.4.5 The SNS View
14.5 Dr. Reddy’s Laboratories Ltd.
14.5.1 Market Overview
14.5.2 Financials
14.5.3 Product/Services/Offerings
14.5.4 SWOT Analysis
14.5.5 The SNS View
14.6 GlaxoSmithKline plc,
14.6.1 Market Overview
14.6.2 Financials
14.6.3 Product/Services/Offerings
14.6.4 SWOT Analysis
14.6.5 The SNS View
14.7 Sanofi.
14.7.1 Market Overview
14.7.2 Financials
14.7.3 Product/Services/Offerings
14.7.4 SWOT Analysis
14.7.5 The SNS View
14.8 Aspen Holdings.
14.8.1 Market Overview
14.8.2 Financials
14.8.3 Product/Services/Offerings
14.8.4 SWOT Analysis
14.8.5 The SNS View
14.9 Fresenius SE & Co.
14.9.1 Market Overview
14.9.2 Financials
14.9.3 Product/Services/Offerings
14.9.4 SWOT Analysis
14.9.5 The SNS View
14.10 Sandoz (Novartis AG).
14.10.1 Market Overview
14.10.2 Financials
14.10.3 Product/Services/Offerings
14.10.4 SWOT Analysis
14.10.5 The SNS View
15. Competitive Landscape
15.1 Competitive Benchmarking
15.2 Market Share Analysis
15.3 Recent Developments
16. USE Cases and Best Practices
17. Conclusion
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